TTBK2 Kinase Activity Assay Service

Activity-based TTBK2 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

TTBK2

Enzyme

Human TTBK2, wt

HGNC

TTBK2

Manning ID

TTBK2

Synonym

KIAA0847, TTBK, SCA11, TTBK2, BDTK, KIAA1855, RP3-330M21.4

UniProt

Q6IQ55 (TTBK2_HUMAN)

Kinase Type

Protein kinase

Kinase Group

CK1

Assay Properties

Assay Format

33PanQinaseTM

Substrates

Casein, ATP

Reaction

Casein + 33P-ATP = 33P-Casein + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 100000
Sorafenib 10000
Sunitinb 100000

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice TTBK2
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

Yes; ProQinaseTM – TTBK2
(Activity verified by 33PanQinaseTM-Assay)

Product Number

1359-0000-1

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