Activity-based ULK2 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
ULK2
Enzyme
Human ULK2
HGNC
ULK2
Synonym
ATG1B, KIAA0623, Unc51.2
Substrates
MBP (Myelin Basic Protein), 10 µM
ATP 10 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
Scientific Information
Q8IYT8 (http://www.uniprot.org/uniprot/Q8IYT8)
Screening Location
Malvern, USA
Reference compound IC50 for ULK2
