Activity-based VRK1 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
VRK1
Enzyme
Human VRK1
HGNC
VRK1
Synonym
VRK1
Assay Properties
Substrates
Casein, 20 µM
ATP, 10 µM
ATP, 10 µM
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
Scientific Information
Q99986 (http://www.uniprot.org/uniprot/Q99986)
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Kinase Assays
Reference compound inhibition of VRK1
