Activity-based WEE1 kinase assay for compound screening and profiling via ADP-Glo kinase assay.
Target Overview
CAT#
WEE1 (ADP-Glo)
Enzyme
Human WEE1
HGNC
WEE1
Synonym
Wee1-like protein kinase, Wee1A kinase, WEE1hu
Assay Properties
Substrates
ATP, 10 µM
Reaction
ATP = ADP + Pi
Readout
ADP-Glo Detection
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| WEE1 Inhibitor | 1.8 |
| Lunresertib (RP-6306) | 35.9 |
| Staurosporine | 872 |
Scientific Information
P30291 (http://www.uniprot.org/uniprot/P30291)
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Kinase Assays
Reference compound inhibition for WEE1
