WNK2 Kinase Assay Service

Activity-based WNK2 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
WNK2

Enzyme
Human WNK2

HGNC
WNK2

Synonym
KIAA1760, NY-CO-43, P/OKcl.13, PRKWNK2, SDCCAG43

Substrates
MBP (Myelin Basic Protein), 20 µM
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Scientific Information
Q9Y3S1 (http://www.uniprot.org/uniprot/Q9Y3S1)

Screening Location
Malvern, USA

Reference compound IC50 for WNK2