WNK3 Kinase Activity Assay Service

Activity-based WNK3 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

WNK3

Enzyme

Human WNK3, wt

HGNC

WNK3

Manning ID

Wnk3

Synonym

KIAA1566, PRKWNK3, WNK3

UniProt

Q9BYP7 (WNK3_HUMAN)

Kinase Type

Protein kinase

Kinase Group

Other

Assay Properties

Assay Format

33PanQinaseTM

Substrates

RB-S6P, ATP

Reaction

RB-S6P + 33P-ATP = 33P-RB-S6P + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
WNK463 13
Sorafenib 10000
Sunitinb 100000

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice WNK3
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

No

Product Number

N/A

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