Reaction Biology offers the largest portfolio of kinase assays in the industry. We are dedicated to provide end-to-end service for kinase drug discovery covering all steps of the preclinical drug discovery process.
The improvement of the selectivity of a compound by screening a large part of the kinome is of pivotal importance in the discovery process of novel kinase inhibitors.
The Cellular Phosphorylation Assay is a kinase activity assay performed in intact cells. The assays have been designed to address compound activity in a physiological environment on a physiological substrate.
The Kinase SubstrateFinder is a biochemical kinase assay that can be used for the identification of suitable substrates for a specific kinase of interest for example for assay development or pathway identification.
Custom-tailored kinase screening and mechanism of action studies can be performed with either our portfolio of assays or with a kinase or substrate provided by the customer.
Genetically engineered tumor models are well suited for the investigation of a single driver of tumor growth such as an overexpressed or constitutively expressed kinase.
