List of Kinase Panels
|Type of KinaseFinder||# of kinases||Assay format|
|Tyr protein kinases||94||³³PanQinase™|
|Ser/Thr protein kinases||245||³³PanQinase™|
|Ser/Thr & Tyr protein kinases||339||³³PanQinase™|
|Wild Type Kinase Panel||376||HotSpot™|
|Custom panel||selected by customer||HotSpot™|
Example data with 50 Ser/Thr kinases.
Activity of kinases with example substrate protein are shown (corrected for substrate background activity). Substrate protein was tested at one concentration. Yellow: Kinase with substrate protein; blue: Kinase without substrate protein (autophosphorylation). A ratio value between substrate phosphorylation and apparent autophosphorylation > 3 may be considered as significant. Performed with the 33PanQinase™ assay. cpm = counts per minute
Setups: Proteins and peptides are accepted as substrates.
Assay format: radiometric screening with 33P-ATP as phosphate donor
Turnaround time: 10 business days for standard projects. Expedited scheduling and data delivery can be arranged prior to commencement of the studies.
Screening location: Assays run with the 33PanQinase™ assay are performed at the German site. Assays run with the HotSpot™ assay are performed at the US site.