BCL-W SPR Assay Service

Surface Plasmon Resonance (SPR) technique for evaluating direct binding of small molecule inhibitors to BCL-W

Target Overview

Target

Bcl-2-like protein 2

HGNC symbol

BCL2L2

Synonyms

BCLW, KIAA0271

Scientific information

Q92843 (https://www.uniprot.org/uniprot/Q92843)

Protein source

Produced at Reaction Biology

Screening location

Malvern, PA, USA

Further information

More information can be found on our website SPR Assay Services for Drug Discovery

Binding kinetics of ABT-737 to BCL-W

Binding kinetics of ABT-737 to BCL-W

The data was collected on a Biacore 8K using single-cycle kinetics. The data was analyzed using a 1:1 kinetic binding model.