BCL-XL SPR Assay Service

Anti-apoptotic protein BCL-XL assay with surface plasmon resonance (SPR) format

Target Overview
Target

Bcl-2-like protein 1 isoform L

HGNC symbol

BCL2L1

Synonyms

BCL-XL

Assay Properties
Scientific information

Q07817 (https://www.uniprot.org/uniprot/Q07817)

Binding kinetics of ABT-737 to BCL-XL

ABT-737 Binding to BCL-XL

 

The data was collected on a Biacore 8K using single-cycle kinetics. BCL-XL was immobilized to the sensor chip and the binding of ABT-737 was measured. The data was analyzed using a 1:1 kinetic binding model.