Surface Plasmon Resonance (SPR) technique for evaluating direct binding of BRD3-1 to molecular inhibitors
Bromodomain-containing protein 3 domain 1 (aa 24-144)
Reaction Biology Cat# RD-11-163
Malvern, PA, USA
More information can be found on our website SPR Assay Services for Drug Discovery
Binding of three BET bromodomain inhibitors to BRD3-1
The data was collected on a Biacore 8K using multi-cycle kinetics. The data was analyzed using a 1:1 kinetic binding model or steady state affinity model to determine binding affinity (KD).