Surface Plasmon Resonance (SPR) technique for evaluating direct binding of BRD4-2 to molecular inhibitors
Target Overview
Target
BRD4-2
HGNC symbol
BRD4-2
Synonyms
Bromodomain-containing protein 4 domain 2, Protein HUNK1
Enzyme
Human BRD4-2
Uniprot page
O60885 (https://www.uniprot.org/uniprot/O60885)
Screening location
Malvern, PA, USA
Further information
More information can be found on our website SPR Assay Services for Drug Discovery
Domain selectivity determined by kinetic profile:
JQ1 and the internal compound RBC-O3A2 were tested against domain 1 (BD1) and domain 2 (BD2) of BRD4 in parallel.
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