BRD4-2 SPR Assay Service

Surface Plasmon Resonance (SPR) technique for evaluating direct binding of BRD4-2 to molecular inhibitors

Target Overview
Target

BRD4-2

HGNC symbol

BRD4-2

Synonyms

Bromodomain-containing protein 4 domain 2, Protein HUNK1

Enzyme

Human BRD4-2

Uniprot page

O60885 (https://www.uniprot.org/uniprot/O60885)

Screening location

Malvern, PA, USA

Further information

More information can be found on our website SPR Assay Services for Drug Discovery

Domain selectivity determined by kinetic profile:


JQ1 and the internal compound RBC-O3A2 were tested against domain 1 (BD1) and domain 2 (BD2) of BRD4 in parallel.

BRD4-2 Domain selectivity