BRDT-1 SPR Assay Service

Surface Plasmon Resonance (SPR) technique for evaluating direct binding of BRDT-1 to molecular inhibitors

Target Overview


Bromodomain testis-specific protein domain 1 (aa 21-137)

HGNC symbol



Cancer/testis antigen 9, RING3-like protein

Uniprot page

Q58F21 (

Protein Source:

Reaction Biology Cat# RD-11-169

Screening location

Malvern, PA, USA

Further information

More information can be found on our website SPR Assay Services for Drug Discovery

Binding of three BET bromodomain inhibitors to BRDT-1


The data was collected on a Biacore 8K using multi-cycle kinetics. The data was analyzed using a 1:1 kinetic binding model or steady state affinity model to determine binding affinity (KD).