Binding assay for CREB-binding protein using a surface plasmon resonance (SPR) technique
Target Overview
Target
CREB-binding protein (Bromodomain), AA 1081-1197
HGNC symbol
CREBBP
Synonyms
Histone lysine acetyltransferase CREBBP, Protein-lysine acetyltransferase CREBBP
Uniprot page
Q92793 (https://www.uniprot.org/uniprot/Q92793)
Screening location
Malvern, PA, USA
Further information
More information can be found on our website SPR Assay Services for Drug Discovery
Binding kinetics of reference compound (I-CPB 112) to the Bromodomain of CREB-binding protein
The data was collected on a Biacore 8K using multi-cycle kinetics. Reduced DMSO conditions were used. The data was analyzed using a steady state affinity model.
PDF