CYP19A for compound screening and profiling assay using a fluorescence-based method to measure cytochrome P450 enzyme activity.
Target Overview
CAT#
CYP19A
Enzyme
Human CYP19A
Synonym
Aromatase, Cytochrome P450 19A1, Estrogen synthase, ARO1, CP19A
Scientific Information
P11511 (http://www.uniprot.org/uniprot/P11511)
Assay Properties
Substrate
Dibenzylfluorescein
Reaction
RH + O₂ + NADPH + H⁺ = ROH + H₂O + oxidized [NADPH—hemoprotein reductase]
Readout
Enzymatic activity
Reference Compound IC50s
Screening Location
Malvern, PA, USA
Further information
More information can be found on our website Cytochrome P450 Assay Services.
Reference compound IC50 for CYP19A
