p300 Bromodomain SPR Assay Service

To test the direct binding to the p300 bromodomain using surface plasmon resonance (SPR) technique

Target Overview


Histone acetyltransferase p300 (Bromodomain), AA 1040-1161

HGNC symbol



EP300, p300

Uniprot page

Q9BYF1 (https://www.uniprot.org/uniprot/Q9BYF1)

Protein Source

Reaction Biology Cat# RD-11-222 (http://reactionbiology-com.3dcartstores.com/EP300-His_p_83.html)

Screening location

Malvern, PA, USA

Further information

More information can be found on our website SPR Assay Services for Drug Discovery

EP300 Bromodomain SPR

The data was collected on a Biacore 8K using multi-cycle kinetics. Data was collected under reduced DMSO conditions. The data was analyzed using a steady state affinity model to determine binding affinity (KD).