NSD2 for direct binding screening and profiling of test substance with surface plasmon resonance (SPR) technique.
NSD2-SET
NSD2
Probable histone-lysine N-methyltransferase NSD2, Multiple myeloma SET domain-containing protein, Nuclear SET domain-containing protein 2, Protein trithorax-5, Wolf-Hirschhorn syndrome candidate 1 protein, WHSC1, KIAA1090, MMSET, TRX5
O96028 (https://www.uniprot.org/uniprotkb/O96028/entry)
Malvern, PA, USA
More information can be found on our website SPR Assay Services for Drug Discovery
Hit confirmation at 25 µM
The data were collected on a Biacore 8K using multi-cycle kinetics. The data were analyzed using a steady state affinity model.
Binding kinetics of SAM/SAH to NSD2-SET domain
The data were collected on a Biacore 8K using multi-cycle kinetics. The data were analyzed using a steady state affinity model.