SHP2 SPR Assay Service

Protein tyrosine phosphatase SHP2 assay with surface plasmon resonance (SPR) technique

Target Overview



HGNC symbol



Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D (PTP-1D), Protein-tyrosine phosphatase 2C (PTP-2C), SH-PTP2, SH-PTP3

Scientific information

Q06124 (

Screening location

Malvern, PA, USA

Further information

More information can be found on our website SPR Assay Services for Drug Discovery

Binding of allosteric inhibitor SHP099 to SHP2

SHP099 Binding SHP2


The data was collected on a Biacore 8K using single-cycle kinetics. SHP2 was immobilized to the sensor chip and the binding of allosteric inhibitor SHP099 was measured. The binding data was analyzed using a 1:1 kinetic binding model.