TPMT for direct binding screening and profiling of test substance with surface plasmon resonance (SPR) technique.
Target Overview
Target
TPMT
HGNC symbol
TPMT
Synonyms
Thiopurine S-methyltransferase
Protein Source
Produced at Reaction Biology (aa 2-245)
Scientific Information
P51580 (https://www.uniprot.org/uniprotkb/P51580/entry)
Screening location
Malvern, PA, USA
Further information
More information can be found on our website SPR Assay Services for Drug Discovery
SAM binding to TPMT
The data were collected on a Biacore 8K using multi-cycle kinetics. The data were analyzed using a steady state affinity model.
SAH binding to TPMT
The data were collected on a Biacore 8K using multi-cycle kinetics. The data were analyzed using a steady state affinity model.
PDF