VHL SPR Assay Service

VHL/EloB/EloC for direct binding screening and profiling of test substance with surface plasmon resonance (SPR) technique.

Target Overview
Target

VHL/EloB/EloC

HGNC symbol

VHL
EloB
EloC

Synonyms

von Hippel-Lindau tumor suppressor
Elongin B
Elongin C

Protein Source

Produced at Reaction Biology

Scientific Information

P40337 (https://www.uniprot.org/uniprotkb/P40337)
Q15370 (https://www.uniprot.org/uniprotkb/Q15370)
Q15369 (https://www.uniprot.org/uniprotkb/Q15369)

Screening location

Malvern, PA, USA

Further information

More information can be found on our website SPR Assay Services for Drug Discovery

VH298 binding to VHL

SAM binding to TPMT

The data were collected on a Biacore 8K using multi-cycle kinetics. The data were analyzed using a 1:1
kinetic binding model and a steady state affinity model.

MZ1 binding to VHL

SAH binding to TPMT

The data were collected on a Biacore 8K using multi-cycle kinetics. The data were analyzed using a 1:1
kinetic binding model and a steady state affinity model.