Wildtype EGFR (AA 671-998) SPR Assay Service

Receptor tyrosine kinase EGFR assay with surface plasmon resonance (SPR) format

Target Overview
Target

Wildtype EGFR (AA 671-998)

HGNC symbol

EGFR

Synonyms

Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1

Assay Properties
Scientific information

P00533 (https://www.uniprot.org/uniprot/P00533)

Binding kinetics of lapatinib to wildtype EGFR

Lapatinib Binding EGFR

 

The data was collected on a Biacore 8K using single-cycle kinetics. Wildtype EGFR (AA 671-998) was captured the sensor chip and the binding of lapatinib was measured. The binding data was analyzed using a 1:1 kinetic binding model.