Wildtype EGFR (aa 671-998) SPR Assay Service

Receptor tyrosine kinase EGFR assay using surface plasmon resonance (SPR) technique

Target Overview


Wildtype EGFR (aa 671-998)

HGNC symbol



Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1

Scientific information

P00533 (https://www.uniprot.org/uniprot/P00533)

Screening location

Malvern, PA, USA

Further information

More information can be found on our website SPR Assay Services for Drug Discovery

Binding kinetics of lapatinib to wildtype EGFR

Lapatinib binding EGFR

The data was collected on a Biacore 8K using single-cycle kinetics. Wildtype EGFR (AA 671-998) was captured the sensor chip and the binding of lapatinib was measured. The binding data was analyzed using a 1:1 kinetic binding model.