Thiophene-pyrazolourea derivatives as potent, orally bioavailable, and isoform-selective jnk3 inhibitors. ACS Medicinal Chemistry Letters, 2021 by Andrew Khouri | Nov 20, 2021
Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery. Nature Communications, 2021 by Andrew Khouri | Nov 20, 2021
Development of an N-Terminal BRD4 Bromodomain-Targeted Degrader. ChemRxiv, 2021 by Andrew Khouri | Jul 6, 2021
A novel orally active HDAC6 inhibitor T‑518 shows a therapeutic potential for Alzheimer’s disease and tauopathy in mice. Scientific Reports, 2021 by Andrew Khouri | Jul 6, 2021
7-(2-Anilinopyrimidin-4-yl)-1-benzazepin-2-ones Designed by a “Cut and Glue” Strategy Are Dual Aurora A/VEGF-R Kinase Inhibitors. Molecules, 2021 by Andrew Khouri | Jul 6, 2021