Intracellular NLRP3 Assay Services
NLRP3 is an innate immune receptor protein that acts as a molecular sensor within cells. The NLRP3 inflammasome is a cytosolic multiprotein complex composed of NLRP3, adapter protein ASC, and inflammatory protease caspase-1 that responds to microbial infection, endogenous danger signals, and environmental stimuli. The assembled NLRP3 inflammasome activates the protease caspase-1 to induce pyroptosis and facilitate the release of IL-1β and IL-18, which contribute to innate immune defense and homeostatic maintenance.
