Biochemical Kinase Assays

Selectivity profiling, screening, and IC50 determination on the industry’s largest kinase activity platform

Direct radiometric activity assays (HotSpot and 33PanQinase) plus luminescent ADP-Glo for lipid kinases. 870+ kinases, native protein and peptide substrates, physiological ATP, delivered from US and EU facilities.

Profiling Selectivity Across the Human Kinome

The human kinome contains more than 500 protein kinases and 20 more lipid kinases that share a conserved ATP-binding catalytic core. That structural homology makes selectivity the central challenge of kinase drug discovery: a compound optimized against one target frequently inhibits others, and off-target kinase inhibition is a leading driver of toxicity and late-stage attrition. Quantitative selectivity profiling, measured directly as inhibition of catalytic activity, rather than inferred from binding, gives medicinal chemistry an accurate parameter to optimize against and surfaces liabilities before they reach the clinic.

How Kinase Profiling Works

Your compound is tested against a defined set of kinases, from a single target to the full kinome, at single-dose or multi-point IC50 format.
Activity of protein kinases are measured by direct radiometric transfer of ³³P-phosphate to substrate; activity of lipid kinases are measured by ADP-Glo.
Results are returned as percent inhibition, activity, or IC50, with raw data and curve fitting in Prism.
Selectivity is visualized on the interactive Kinase Mapper across the kinome tree.

See all targets

Our Services

Kinase Selectivity Profiling

Screen one subfamily or the entire human kinome with a large collection of predefined panels plus free-choice selections. IC50-based profiling delivers a quantitative selectivity parameter for medicinal chemistry optimization and off-target assessment, visualized on the Kinase Mapper.

Single-Target Activity and IC50

Hit confirmation, dose-response, and mechanism studies on individual kinases. Profile wild-type and clinically relevant mutants side by side, and resolve ATP-competitive, substrate-competitive, covalent, and allosteric modes of inhibition.

Library and Fragment Screening

High-throughput primary screening of your library or ours, from diverse small molecules to focused, FDA-approved, and covalent fragment collections. Cherry-picking, compound management, and IC50 follow-up are available end to end.

Custom Assay Development

Targets outside the standard library are built to order: plasmid construction, expression, purification, substrate identification, and assay optimization for specialized requirements, such as time dependent inhibition, covalent binding, or inhibition of inactive forms. Native peptide and full-length protein substrates are supported without modification.

Detection Technologies

	HotSpot (Malvern, US)	33PanQinase (Freiburg, DE)	ADP-Glo (both sites)
Detection principle	Radiometric 33P, filter-membrane capture	Radiometric 33P, scintillant ScintiPlate capture	Luminescent ADP detection (Promega)
What it measures	Phosphorylated substrate, direct	Phosphorylated substrate, direct	ADP formation, indirect measure of phosphorylation
Substrates	Native peptide and full-length protein	Native peptide and full-length protein	Primarily lipid kinase substrates
ATP conditions	1 µM, 10 µM, apparent ATP-Km to 100 µM or 1 mM physiological conditions	Apparent ATP-Km	Up to 1 mM
Kinetics	Time-course reads available	Endpoint	Endpoint
Library	~830 assays, deepest mutant and fusion coverage	~517 assays, CDK/cyclin complexes and fragment constructs	23+ lipid kinases

Biochemical Kinase Assays Explained

HotSpot^TM from Reaction Biology is the gold-standard radiometric assay and default choice for most kinase programs. It measures the catalytic event of phosphorylation directly, transferring 33P-phosphate from ATP onto substrate and capturing the phosphorylated product on a filter membrane at our US facility. The assay protocol for HotSpot is available here.

33PanQinase^TM applies the same direct radiometric chemistry at our European facility, capturing product on scintillant-coated ScintiPlates, and adds complementary coverage including CDK/cyclin complexes. The assay protocol for 33PanQinase is available here.

ADP-Glo is a complementary luminescent format that measures the ADP byproduct of the kinase reaction and is the required format for lipid kinases.

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Platform Advantages

Direct Activity Measurement

We measure phosphate transferred to substrate, the catalytic event itself, not binding, ADP, or FRET proxies. Binding does not equal inhibition, and proxy readouts cannot distinguish active-site engagement from non-functional binding.

The Largest Kinase Library

870+ kinase assays including 260+ clinically relevant mutants and 32 oncogenic fusion proteins, the broadest commercially available activity-based panel.

Native, Unmodified Substrates

Full-length proteins and native peptides are accepted without labeling or chemical modification, unlike platforms restricted to modified Sox-peptides, peptide-only, or FRET-labeled substrates.

Physiological ATP Without Compromise

Radiometric detection is unaffected by high ATP, so assays run at physiological 1 mM ATP without the signal degradation seen on luminescent and fluorescent platforms. Available for 340 wild-type kinases in HotSpot format.

Slow-Binding and Covalent Inhibitors

Compound can be pre-incubated with kinase before ATP and substrate are added, up to about two hours on request, to detect slow-binding and time-dependent inhibitors.

Dual-Site US and EU Delivery

The only kinase CRO running radiometric activity assays at both a US and a European facility. EU clients avoid trans-Atlantic compound shipping, and the two sites carry complementary specializations.

High-Throughput Automation

Echo acoustic dispensing and automated liquid handling support primary screening at scale across the library.

Predictable Turnaround

Typical panels and projects completed within 10-15 business days. Single-target and custom work is reported in 10 business days, regardless of compound receipt date. Expedited timelines are available.

Assay Setup and Requirements

US Facility (HotSpot)

Formats: 2-data-point projects at 1 concentration. 5 or 10-dose response curves.
Available assays: Protein kinases via radiometric HotSpot; lipid kinases via ADP-Glo. HotSpot assay protocol available on request
ATP: 1 µM, 10 µM, apparent ATP-Km to 100 µM or 1 mM physiological conditions
Controls: DMSO only as full enzymatic activity control; one kinase-specific control compound included in 10-dose IC50 format for every kinase
Reporting: Raw data, percent enzyme activity, and control compound IC50 values in Excel; assay conditions, target, and substrate information on request
Compound requirement: 20-100 µl of a 10 mM DMSO stock, or solid material
The assay protocol for HotSpot is available here.

German Facility (PanQinase)

Formats: 2-data-point projects at 1 concentration in duplicate or 2 concentrations in singlicate; IC50 at 6 log concentrations or 10 semi-log concentrations in singlicate
Available assays: Protein kinases via radiometric 33PanQinase; lipid kinases via ADP-Glo. 33PanQinase assay protocol available on request
ATP: Apparent ATP-Km
Controls: DMSO only as full enzymatic activity control; one kinase-specific control compound included in 10-dose IC50 format for every kinase
Reporting: Detailed report including assay conditions, target, and substrate information; raw data, percent enzyme activity, IC50, and curve fitting in Excel
Compound requirement: 1 concentration in duplicate, 1900 µl of a 100× stock; 2 concentrations in singlicate, 950 µl of 100× stocks of each concentration; IC50, 1100 µl of a 100× stock. Solid material accepted
The assay protocol for 33PanQinase is available here.

Screening schedule and turnaround

US selectivity panels run bi-weekly; reports 10–15 business days after project start
German selectivity panels run monthly or on demand; reports 10 business days after project start
See upcoming screening deadlines

Data, reporting, and the Kinase Mapper

Standard readouts: percent inhibition or IC50 with dose-response curves
All data delivered in Excel; conditions and substrate detail available on request
Compound selectivity is visualized across the kinome tree with the interactive Kinase Mapper

Libraries available for screening

Standard: Diverse small-molecule libraries, 110,000+ compounds
Focused libraries: kinase inhibitors, FDA-approved inhibitors, epigenetic inhibitors, natural products, clinical collection
Fragment libraries: standard diverse, Fsp3-enriched, 3D, protein-protein interaction, and covalent fragments

Selectivity, Mechanism, and Reproducibility

Why profile with IC50 values

Protein kinases share a conserved catalytic core and high structural and sequence similarity, which limits inhibitor selectivity and can produce off-target toxicity that ends otherwise promising candidates. IC50-based profiling quantifies how potency differs across the kinome, enabling a precise judgment of selectivity. It is designed to:

1. Provide an accurate guiding parameter for optimizing kinase selectivity during medicinal chemistry
2. Confirm that observed functional effects are driven by the intended target and not off-target kinases, and surface potential adverse effects early
3. Provide an accurate comparison against a reference compound

Mechanism of action via SAR

Structure-activity relationship analysis with IC50 potency assays elucidates how a shortlisted inhibitor engages its target. By comparing IC50 values across the wild-type kinase and variants carrying targeted domain mutations, we resolve the critical binding interactions and classify the inhibitor as covalent, ATP-competitive, or substrate-competitive. This confirms the activity profile and directs targeted optimization.

Reproducibility: BCR-ABL inhibitor (33PanQinase)

IC50 values of a BCR-ABL kinase inhibitor were determined for 320 wild-type kinases across two independent experiments and compared. The high R-squared value shows strong correlation between runs. IC50 was determined with 6 compound concentrations in singlicate using the 33PanQinase assay.

Reproducibility: Staurosporine control (HotSpot)

The control compound staurosporine was tested over 6 months across 12 independent experiments. IC50 was determined with 10 compound concentrations in singlicate using the HotSpot assay, demonstrating long-term assay stability.

Selectivity profiling: FLT3 inhibitor (33PanQinase)

IC50 values for an FLT3 inhibitor were determined across 320 wild-type protein kinases, with the lowest-IC50 targets named. Profiling at this scale distinguishes potency differences across the kinome and supports a precise selectivity judgment.

Frequently asked questions

What is kinase selectivity profiling and why does it matter?

It is the testing of a compound against many kinases to quantify how selectively it inhibits its intended target. Because kinases share a conserved ATP-binding site, off-target inhibition is common and is a leading cause of toxicity and attrition, so selectivity data directly informs candidate selection and optimization.

What is the difference between HotSpot and 33PanQinase?

Both are radiometric activity assays that measure phosphorylation directly using 33P. HotSpot, run in the US, captures phosphorylated substrate on a filter membrane. 33PanQinase, run in Germany, uses scintillant-coated ScintiPlates. They differ in capture format, assay conditions, and site, and they carry complementary target coverage.

Why radiometric detection instead of fluorescent or luminescent?

Radiometric assays measure the catalytic event of phosphorylation directly, so they are not subject to the optical interference and signal degradation that affect coupled luminescent and fluorescent formats, and they remain reliable at physiological 1 mM ATP.

Do you measure activity or binding?

Activity. We quantify inhibition of catalytic phosphoryl transfer. Binding-based panels report displacement, which cannot distinguish active-site inhibition from non-functional binding and run without ATP in the reaction.

Can you run assays at physiological ATP?

Yes. Radiometric detection is unaffected by high ATP, and 1 mM ATP is available for 340 wild-type kinases on the HotSpot platform, in addition to standard concentrations of 1 µM, 10 µM, and apparent ATP-Km.

How many kinases and which panels do you offer?

870+ kinase assays, including 260+ clinically relevant mutants, 32 oncogenic fusions, and lipid kinases. Choose a predefined panel, a specialty mutant profiler, or a free-choice selection of any targets in the library.

Can you detect slow-binding or covalent inhibitors?

Yes. Compound can be pre-incubated with the kinase/substate mixture for varying time before ATP addition to reveal slow-binding and time-dependent inhibition. Time-course reads are available on HotSpot assay to further characterize kinetic parameters of slow binding inhibitors

What do I need to send, and how long does it take?

Requirements differ by site. For HotSpot (US) panel profiling, send 100 µl of a 10 mM DMSO stock, or solid material. For 33PanQinase (Germany), send a 100x stock in 100% DMSO: 1900 µl for one concentration in duplicate; 950 µl of each concentration for two concentrations in singlicate; or, for a 6-point IC50, 1100 µl at the highest assay concentration. Solid material is also accepted. Most panels are reported in 10 to 15 business days, and single-target or custom work in 10 business days, regardless of when compound is received.

Targets and Panels

All Targets

Target	HGNC Reference	Uniprot #	Additional Synonyms	US	Germany	Classification	US Panels	Germany Panels
AAK1	AAK1	Q2M2I8	AP2-associated protein kinase 1, KIAA1048, Adaptor-associated kinase 1	Probe-displacement		Protein kinase
ABL1	ABL1	P00519	ABL, JTK7, p150, c-ABL, v-abl	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
ABL1 (E255K)	ABL1 (E255K)	P00519	ABL, JTK7, p150, c-ABL, v-abl	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ABL1 (E255V)	ABL1 (E255V)	P00519	ABL, JTK7, p150, c-ABL, v-abl	HotSpot^™		Protein kinase	Mutant Panel
ABL1 (F317I)	ABL1 (F317I)	P00519	ABL, JTK7, p150, c-ABL, v-abl	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ABL1 (F317L)	ABL1 (F317L)	P00519	ABL, JTK7, p150, c-ABL, v-abl	HotSpot^™		Protein kinase	Mutant Panel
ABL1 (G250E)	ABL1 (G250E)	P00519	ABL, JTK7, p150, c-ABL, v-abl	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ABL1 (H396P)	ABL1 (H396P)	P00519	ABL, JTK7, p150, c-ABL, v-abl	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ABL1 (M351T)	ABL1 (M351T)	P00519	ABL, JTK7, p150, c-ABL, v-abl	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ABL1 (Q252H)	ABL1 (Q252H)	P00519	ABL, JTK7, p150, c-ABL, v-abl	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ABL1 (T315I)	ABL1 (T315I)	P00519	ABL, JTK7, p150, c-ABL, v-abl	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ABL1 (V299L)	ABL1 (V299L)	P00519	ABL, JTK7, p150, c-ABL, v-abl	HotSpot^™		Protein kinase	Mutant Panel
ABL1 (Y245F)	ABL1 (Y245F)	P00519	ABL, JTK7, p150, c-ABL, v-abl	HotSpot^™		Protein kinase	Mutant Panel
ABL1 (Y245F/Y412F)	ABL1 (Y245F/Y412F)	P00519	ABL, JTK7, p150, c-ABL, v-abl	HotSpot^™		Protein kinase	Mutant Panel
ABL1 (Y253F)	ABL1 (Y253F)	P00519	ABL, JTK7, p150, c-ABL, v-abl	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ABL1 (Y253H)	ABL1 (Y253H)	P00519	ABL, JTK7, p150, c-ABL, v-abl	HotSpot^™		Protein kinase	Mutant Panel
ABL2/ARG	ABL2	P42684	ABLL, ARG	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
ACK1	TNK2	Q07912	ACK, p21cdc42Hs, Activated CDC42 kinase 1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
ACVR2A	ACVR2A	P27037	ACVR2, ACTRII		³³PanQinase^™	Protein kinase		Wild Type Panel
ACVR2B	ACVR2B	Q13705	ActR-IIB, ACTRIIB		³³PanQinase^™	Protein kinase		Wild Type Panel
ADK	ADK	P55263	Adenosine 5′-phosphotransferase, AK	ADP-Glo		Small molecule
AKT1	AKT1	P31749	PKB, RAC, PRKBA, RAc-ALPHA	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
AKT1 (E17K)	AKT1 (E17K)	P31749	PKB, RAC, PRKBA, RAc-ALPHA	HotSpot^™	³³PanQinase^™	Protein kinase	Mutant Panel
AKT1 aa106-480	AKT1 (aa106-480)	P31749	PKB, RAC, PRKBA, RAc-ALPHA		³³PanQinase^™, ADP-Glo	Protein kinase
AKT2	AKT2	P31751	PRKBB, PKBBETA, RAc-BETA	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
AKT2 (E17K)	AKT2 (E17K)	P31751	PRKBB, PKBBETA, RAc-BETA	HotSpot^™		Protein kinase	Mutant Panel
AKT2 aa107-481	AKT2 (aa107-481)	P31751	PRKBB, PKBBETA, RAc-BETA		³³PanQinase^™, ADP-Glo	Protein kinase
AKT3	AKT3	Q9Y243	PKBG, PKB gamma, PRKBG, RAC-gamma, RAC-PK-gamma, STK-2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
AKT3 (E17K)	AKT3 (E17K)	Q9Y243	PKBG, PKB gamma, PRKBG, RAC-gamma, RAC-PK-gamma, STK-2	HotSpot^™		Protein kinase	Mutant Panel
AKT3 (G171R)	AKT3 (G171R)	Q9Y243	PKBG, PKB gamma, PRKBG, RAC-gamma, RAC-PK-gamma, STK-2	HotSpot^™		Protein kinase	Mutant Panel
AKT3 aa106-479	AKT3 (aa106-479)	Q9Y243	PKBG, PKB gamma, PRKBG, RAC-gamma, RAC-PK-gamma, STK-2		³³PanQinase^™, ADP-Glo	Protein kinase
ALK	ALK	Q9UM73	CD246, NBLST3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
ALK (C1156Y)	ALK (C1156Y)	Q9UM73	CD246, NBLST3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ALK (F1174L)	ALK (F1174L)	Q9UM73	CD246, NBLST3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ALK (F1174L)-EML4	ALK (F1174L)-EML4	A6P4T4	CD246, NBLST3, EML4-ALK (F1174L)	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ALK (F1174L)-NPM1	ALK (F1174L)-NPM1	P06748, Q9UM73	CD246, NBLST3, NPM1-ALK (F1174L)	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ALK (F1174S)	ALK (F1174S)	Q9UM73	CD246, NBLST3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ALK (G1202R)	ALK (G1202R)	Q9UM73	CD246, NBLST3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ALK (G1269A)	ALK (G1269A)	Q9UM73	CD246, NBLST3	HotSpot^™		Protein kinase	Mutant Panel
ALK (G1269S)	ALK (G1269S)	Q9UM73	CD246, NBLST3	HotSpot^™		Protein kinase	Mutant Panel
ALK (I1171N/D1203N)	ALK (I1171N/D1203N)	Q9UM73	ALK tyrosine kinase receptor, Anaplastic lymphoma kinase, CD246	HotSpot^™		Protein kinase	Mutant Panel
ALK (L1152R)	ALK (L1152R)	Q9UM73	CD246, NBLST3	HotSpot^™		Protein kinase	Mutant Panel
ALK (L1196M)	ALK (L1196M)	Q9UM73	CD246, NBLST3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ALK (L1196M/G1202R)	ALK (L1196M/G1202R)	Q9UM73	CD246	HotSpot^™		Protein kinase	Mutant Panel
ALK (R1275Q)	ALK (R1275Q)	Q9UM73	CD246, NBLST3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ALK (S1206R)	ALK (S1206R)	Q9UM73	CD246, NBLST3	HotSpot^™		Protein kinase	Mutant Panel
ALK (T1151-L1152insT)	ALK (T1151-L1152insT)	Q9UM73	CD246, NBLST3	HotSpot^™		Protein kinase	Mutant Panel
ALK (T1151M)	ALK (T1151M)	Q9UM73	CD246, NBLST3	HotSpot^™		Protein kinase	Mutant Panel
ALK1/ACVRL1	ACVRL1	P37023	ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
ALK2 (Q207D)	ACVR1 (Q207D)	Q04771	ACTRI, ACVRLK2, ALK2, SKR1	HotSpot^™		Protein kinase	Mutant Panel
ALK2 (R206H)	ACVR1 (R206H)	Q04771	ACTRI, ACVRLK2, ALK2, SKR1	HotSpot^™		Protein kinase	Mutant Panel
ALK2/ACVR1	ACVR1	Q04771	ACTRI, ACVRLK2, ALK2, SKR1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
ALK3/BMPR1A	BMPR1A	P36894	SKR5, CD292, ALK3, ACVRLK3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
ALK4/ACVR1B	ACVR1B	P36896	ACTRIB, ACVRLK4, ALK4, SKR2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
ALK5/TGFBR1	TGFBR1	P36897	ALK5, ACVRLK4	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
ALK6/BMPR1B	BMPR1B	O00238	ALK6, CDw293	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
ALK-EML4 (Eex13Aex20)	ALK-EML4	Q9HC35, Q9UM73	CD246, EMAP-4	HotSpot^™		Protein kinase	Mutant Panel
ALK-EML4 (Eex14Aex20)	ALK-EML4	Q9HC35, Q9UM73	CD246, EMAP-4	HotSpot^™		Protein kinase	Mutant Panel
ALK-EML4 (Eex20Aex20)	ALK-EML4	Q9HC35, Q9UM73	CD246, EMAP-4	HotSpot^™		Protein kinase	Mutant Panel
ALK-EML4 (Eex6Aex20)	ALK-EML4	Q9HC35, Q9UM73	CD246, EMAP-4	HotSpot^™		Protein kinase	Mutant Panel
ALK-KIF5B (Kex24Aex20)	ALK-KIF5B	P33176, Q9UM73	CD246, NBLST3, KIF5B-ALK	HotSpot^™		Protein kinase	Mutant Panel
ALK-KLC1 (Kex8Aex20)	ALK-KLC1	Q07866, Q9UM73	CD246, NBLST3, KCL1-ALK	HotSpot^™		Protein kinase	Mutant Panel
ALK-NPM1	ALK-NPM1	P06748, Q9UM73	CD246, NBLST3, NPM1-ALK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
ALK-STRN (Sex3Aex20)	ALK-STRN	O43815, Q9UM73	CD246, Striatin	HotSpot^™		Protein kinase	Mutant Panel
ALK-TFG	ALK-TFG	Q92734, Q9UM73	CD246, NBLST3, TFG-ALK	HotSpot^™		Protein kinase	Mutant Panel
ALK-TFG (Tex4Aex20)	ALK-TFG	Q92734, Q9UM73	CD246, NBLST3, TFG-ALK	HotSpot^™		Protein kinase	Mutant Panel
ALK-TPM1	ALK-TPM1	P09493, Q9UM73	CD246, NBLST3, TPM1-ALK	HotSpot^™		Protein kinase	Mutant Panel
ALK-TPM3	ALK-TPM3	P06753, Q9UM73	CD246, NBLST3, TPM3-ALK	HotSpot^™		Protein kinase	Mutant Panel
AMPK (A1/B1/G1)	PRKAA1-PRKAB1-PRKAG1	Q13131, Q9Y478, P54619	AMPK (A1/B1/G1)	HotSpot^™		Protein kinase	Atypical Panel
AMPK (A1/B1/G2)	PRKAA1-PRKAB1-PRKAG2	Q13131, Q9Y478, Q9UGJ0	AMPK (A1/B1/G2)	HotSpot^™		Protein kinase	Atypical Panel
AMPK (A1/B1/G3)	PRKAA1-PRKAB1-PRKAG3	Q13131, Q9Y478, Q9UGI9	AMPK (A1/B1/G3)	HotSpot^™		Protein kinase	Atypical Panel
AMPK (A1/B2/G1)	PRKAA1-PRKAB2-PRKAG1	Q13131, O43741, P54619	AMPK (A1/B2/G1)	HotSpot^™		Protein kinase	Atypical Panel
AMPK (A1/B2/G2)	PRKAA1-PRKAB2-PRKAG2	Q13131, O43741, Q9UGJ0	AMPK (A1/B2/G2)	HotSpot^™		Protein kinase	Atypical Panel
AMPK (A1/B2/G3)	PRKAA1-PRKAB2-PRKAG3	Q13131, O43741, Q9UGI9	AMPK (A1/B2/G3)	HotSpot^™		Protein kinase	Atypical Panel
AMPK (A2/B1/G1)	PRKAA2-PRKAB1-PRKAG1	P54646, Q9Y478, P54619	AMPK (A2/B1/G1)	HotSpot^™		Protein kinase	Atypical Panel
AMPK (A2/B1/G2)	PRKAA2-PRKAB1-PRKAG2	P54646, Q9Y478, Q9UGJ0	AMPK (A2/B1/G2)	HotSpot^™		Protein kinase	Atypical Panel
AMPK (A2/B1/G3)	PRKAA2-PRKAB1-PRKAG3	P54646, Q9Y478, Q9UGI9	AMPK (A2/B1/G3)	HotSpot^™		Protein kinase	Atypical Panel
AMPK (A2/B2/G1)	PRKAA2-PRKAB2-PRKAG1	P54646, O43741, P54619	AMPK (A2/B2/G1)	HotSpot^™		Protein kinase	Atypical Panel
AMPK (A2/B2/G2)	PRKAA2-PRKAB2-PRKAG2	P54646, O43741, Q9UGJ0	AMPK (A2/B2/G2)	HotSpot^™		Protein kinase	Atypical Panel
AMPK (A2/B2/G3)	PRKAA2-PRKAB2-PRKAG3	P54646, O43741, Q9UGI9	AMPK (A2/B2/G3)	HotSpot^™		Protein kinase	Atypical Panel
AMPKalpha1	PRKAA1	Q13131	AMPK A1		³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
AMPKalpha1 aa1-312*	PRKAA1 (aa1-312)	Q13131	AMPK A1		³³PanQinase^™, ADP-Glo	Protein kinase
ARAF	ARAF (Y301D/Y302D)	P10398	A-RA, ARAF1, PKS2, RAFA1, ARAF YDYD	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
ARK5/NUAK1	NUAK1	O60285	KIAA0537, ARK5	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
ASK1/MAP3K5	MAP3K5	Q99683	ASK1, MAPKKK5, MEKK5	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
ATM	ATM	Q13315	TEL1, TELO1	HTRF		Protein kinase
ATR	ATR	Q13535	FRP1, Ataxia telangiectasia and Rad3-related protein, FRAP-related protein 1	HTRF		Protein kinase
Aurora A	AURKA	O14965	AurA, AIK, ARK1, AURA, BTAK, STK15, AuroraA, Aurora A	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
Aurora B	AURKB	Q96GD4	AurB, AIK2, AIM1, ARK2, AurB, IPL1, STK5, AuroraB, Aurora B	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
Aurora B (G160L)	AURKB (G160L)	Q96GD4	AurB, AIK2, AIM1, ARK2, AurB, IPL1, STK5, AuroraB, Aurora B	HotSpot^™		Protein kinase	Mutant Panel
Aurora C	AURKC	Q9UQB9	AurC, AIE2, AIK3, STK13, Aurora C, AuroraC	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
AXL	AXL	P30530	EC, UFO	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
AXL (R499C)	AXL (R199C)	P30530	EC, UFO	HotSpot^™		Protein kinase	Mutant Panel
BLK	BLK	P51451	BLK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
BMPR2	BMPR2	Q13873	BMPR-II, BMPR3, BMR2, BRK-3, PPH1, T-ALK	HotSpotb, ADP-Glo, Probe-displacement		Protein kinase
BMX/ETK	BMX	P51813	ETK, PSCTK2, PSCTK3	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
BRAF	BRAF	P15056	B-Raf, B-raf-1, BRAF1, RAFB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
BRAF (d485-489/P490Y)	BRAF (d485-489/P490Y)	P15056	B-Raf, B-raf-1, BRAF1, RAFB1	HotSpot^™		Protein kinase	Mutant Panel
BRAF (G464V)	BRAF (G464V)	P15056	B-Raf, B-raf-1, BRAF1, RAFB1	HotSpot^™		Protein kinase	Mutant Panel
BRAF (G469A)	BRAF (G469A)	P15056	B-Raf, B-raf-1, BRAF1, RAFB1	HotSpot^™		Protein kinase	Mutant Panel
BRAF (K601E)	BRAF (K601E)	P15056	B-Raf, B-raf-1, BRAF1, RAFB1	HotSpot^™		Protein kinase	Mutant Panel
BRAF (L597V)	BRAF (L597V)	P15056	B-Raf, B-raf-1, BRAF1, RAFB1	HotSpot^™		Protein kinase	Mutant Panel
BRAF (R506_K507insVLR)	BRAF (R506_K507insVLR)	P15056	B-Raf, B-raf-1, BRAF1, RAFB1	HotSpot^™		Protein kinase	Mutant Panel
BRAF (T599_V600insT)	BRAF (T599_V600insT)	P15056	B-Raf, B-raf-1, BRAF1, RAFB1	HotSpot^™		Protein kinase	Mutant Panel
BRAF (V599E)	BRAF (V600E)	P15056	B-Raf, B-raf-1, BRAF1, RAFB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
BRAF (V600A)	BRAF (V600A)	P15056	B-Raf, B-raf-1, BRAF1, RAFB1	HotSpot^™		Protein kinase	Mutant Panel
BRAF (V600D)	BRAF (V600D)	P15056	B-Raf, B-raf-1, BRAF1, RAFB1	HotSpot^™		Protein kinase	Mutant Panel
BRAF (V600K)	BRAF (V600K)	P15056	B-Raf, B-raf-1, BRAF1, RAFB1	HotSpot^™		Protein kinase	Mutant Panel
BRAF-FAM131B	BRAF-FAM131B	Q86XD5, P15056	B-Raf, B-raf-1, BRAF1, RAFB1, FAM131B-BRAF	HotSpot^™		Protein kinase	Mutant Panel
BRAF-KIAA1549 (Kex15Bex9)	BRAF-KIAA1549 (Kex15Bex9)	Q9HCM3, P15056	B-Raf, B-raf-1, BRAF1, RAFB1, KIAA1549-BRAF	HotSpot^™		Protein kinase	Mutant Panel
BRAF-KIAA1549 (Kex16Bex9)	BRAF-KIAA1549 (Kex16Bex9)	Q9HCM3, P15056	B-Raf, B-raf-1, BRAF1, RAFB1, KIAA1549-BRAF	HotSpot^™		Protein kinase	Mutant Panel
BRAF-SRGAP3 (Sex12Bex9)	BRAF-SRGAP3	O43295, P15056	B-Raf, B-raf-1, BRAF1, RAFB1, SRGAP3-BRAF	HotSpot^™		Protein kinase	Mutant Panel
BRK	PTK6	Q13882	BRK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
BRSK1	BRSK1	Q8TDC3	KIAA1811	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
BRSK2	BRSK2	Q8IWQ3	C11orf7, FLJ41362, HUSSY-12, PEN11B, SAD1, STK29	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
BTK	BTK	Q06187	AGMX1, AT, ATK, BPK, PSCTK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
BTK (C481S)	BTK (C481S)	Q06187	AGMX1, AT, ATK, BPK, PSCTK1	HotSpot^™		Protein kinase	Mutant Panel
BTK (E41K)	BTK (E41K)	Q06187	AGMX1, AT, ATK, BPK, PSCTK1	HotSpot^™		Protein kinase	Mutant Panel
BTK (P190K)	BTK (P190K)	Q06187	AGMX1, AT, ATK, BPK, PSCTK1	HotSpot^™		Protein kinase	Mutant Panel
BTK (T474I)	BTK (T474I)	Q06187	AGMX1, AT, ATK, BPK, PSCTK1	HotSpot^™		Protein kinase	Mutant Panel
BTK (Y485F)	BTK (Y485F)	Q06187	AGMX1, AT, ATK, BPK, PSCTK1	HotSpot^™		Protein kinase	Mutant Panel
BUB1B	BUB1B	O60566	BUBR1, Bub1A, MAD3L, hBUBR1		³³PanQinase^™	Protein kinase		Wild Type Panel
CAMK1a	CAMK1	Q14012	CAMK1-PEN, CAMKI	HotSpot^™		Protein kinase	Wild Type Panel, Diversify Panel
CAMK1b	PNCK	Q6P2M8	CAMK1b, MGC45419	HotSpot^™		Protein kinase	Wild Type Panel
CAMK1d	CAMK1D	Q8IU85	CKLiK, CaM-K1, CaMKID	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel, Diversify Panel
CAMK1g	CAMK1G	Q96NX5	CLICKIII, VWS1, dJ272L16.1	HotSpot^™		Protein kinase	Wild Type Panel
CAMK2a	CAMK2A	Q9UQM7	CAMKA, KIAA0968	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CAMK2b	CAMK2B	Q13554	CAM2, CAMK2, CAMKB, MGC29528	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CAMK2d	CAMK2D	Q13557	CAMKD, MGC44911, CaMKII delta	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CAMK2g	CAMK2G	Q13555	CAMK, CAMK-II, CAMKG, MGC26678	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CAMK4	CAMK4	Q16566	CaMK-GR, MGC36771	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CAMKK1	CAMKK1	Q8N5S9	CAMKKA, DKFZp761M0423, MGC34095	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CAMKK2	CAMKK2	Q96RR4	CAMKK, CAMKKB, KIAA0787, MGC15254	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CASK	CASK	P07498	CSN3, CSN10, CSNK, Kappa-casein	Probe-displacement		Protein kinase
CDC7/DBF4	CDC7-DBF4	O00311, Q9UBU7	CDC7L1, HsCdc7, HsCDC7, Hsk1, huCdc7	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK1/CycA2	CDK1-CCNA2	P06493	CDC2, p34		³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
CDK1/CycE2	CDK1	P06493	CDK1, CDC2, p34		³³PanQinase^™	Protein kinase		Wild Type Panel
CDK1/cyclin A	CDK1-CCNA2	P06493, P20248	CDC2, p34	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CDK1/cyclin B	CDK1-CCNB1	P06493	CDC2, p34	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
CDK1/cyclin E	CDK1-CCNE1	P06493, P24864	CDC2, p34	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK1/CycO	CDK1	P06493	CDK1, CDC2, p34		³³PanQinase^™	Protein kinase		Wild Type Panel
CDK10/CycQ	CDK10-CCNQ	Q15131	PISSLRE		³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
CDK11B/Cyclin K	CDK11B-CCNK	P21127, O75909	Cyclin-dependent kinase 11B, CDC2L1, PITSLREA, PK58, CPR4, CCNK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
CDK12 (R722C)/cyclin K	CDK12 (R722C)-CCNK	Q9NYV4, O75909	CRKRS, CRK7	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
CDK12/cyclin K	CDK12-CCNK	Q9NYV4, O75909	CRKRS, CRK7	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK13/cyclin K	CDK13-CCNK	Q14004, O75909	CDC2L, CDC2L5, CHED	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK14/cyclin Y (PFTK1)	CDK14-CCNY	O94921, Q8ND76	PFTAIRE1, PFTK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK15/Cyclin A2	CDK15-CCNA2	Q96Q40, P20248	Cyclin-dependent kinase 15, Cell division protein kinase 15, PFTK2, CCNA2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK15/Cyclin B1	CDK15-CCNB1	Q96Q40, P14635	PFTK2, CCNB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK16/cyclin Y	CDK16-CCNY	Q00536, Q8ND76	PCTAIRE1, PCTAIRE, PCTGAIRE, PCTK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK17/cyclin Y	CDK17-CCNY	Q00537, Q8ND76	PCTAIRE2, PCTK2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CDK17/p35NCK	CDK17-CDK5R1	Q00537	PCTAIRE2, PCTK2		³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
CDK18/cyclin Y	CDK18-CCNY	Q07002, Q8ND76	PCTAIRE, PCTAIRE3, PCTK3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK19/cyclin C	CDK19-CCNC	Q9BWU1, P24863	CDC2L6, CDK11	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK2/CycD1	CDK2-CCND1	P24941	p33		³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
CDK2/cyclin A	CDK2-CCNA2	P24941, P20248	p33	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK2/cyclin A1	CDK2-CCNA1	P24941, P78396	p33	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CDK2/cyclin E	CDK2-CCNE1	P24941, P24864	p33	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK2/cyclin E2	CDK2-CCNE2	P24941, O96020	p33	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CDK2/cyclin O	CDK2-CCNO	P24941, P22674	p33	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CDK20/CycH	CDK20-CCNH	Q8IZL9	CAK-kinase p42, CCRK, CDCH, p42, PNQALRE		³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
CDK20/CycT1	CDK20-CCNT1	Q8IZL9	CAK-kinase p42, CCRK, CDCH, p42, PNQALRE		³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
CDK3/Cyclin C	CDK3-CCNC	Q00526, P24863	Cyclin-dependent kinase 3, CCNC	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK3/cyclin E	CDK3-CCNE1	Q00526, P24864	CDKN3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK3/cyclin E2	CDK3-CCNE2	Q00526, O96020	CDKN3	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CDK3/CycO	CDK3	Q00526	CDK3, CDKN3		³³PanQinase^™	Protein kinase		Wild Type Panel
CDK4/cyclin D1	CDK4-CCND1	P11802, P24385	CMM3, PSK-J3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
CDK4/cyclin D2	CDK4-CCND2	P11802, P30279	CMM3, PSK-J3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK4/cyclin D3	CDK4-CCND3	P11802, P30281	CMM3, PSK-J3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK5/p25	CDK5-CDK5R1 (p25)	Q00535, Q15078	PSSALRE	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK5/p35	CDK5-CDK5R1	Q00535, Q15078	PSSALRE	HotSpot^™		Protein kinase	Wild Type Panel
CDK5/p35NCK	CDK5-CDK5R1	Q00535	PSSALRE		³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
CDK6/cyclin D1	CDK6-CCND1	Q00534, P24385	PLSTIRE	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK6/cyclin D2	CDK6-CCND2	Q00534, P30279	PLSTIRE	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK6/cyclin D3	CDK6-CCND3	Q00534, P30281	PLSTIRE	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK7/cyclin H/MNAT1	CDK7-CCNH-MNAT1	P50613, P51946, P51948	CAK1, CDKN7, STK1, p39MO15	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
CDK8/cyclin C	CDK8-CCNC	P49336, P24863	K35	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK9/cyclin K	CDK9-CCNK	P50750, O75909	C-2k, CDC2L4, PITALRE, TAK, CDC2-related kinase	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK9/cyclin T1	CDK9-CCNT1	P50750, O60563	C-2k, CDC2L4, PITALRE, TAK, CDC2-related kinase	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CDK9/cyclin T2	CDK9-CCNT2	P50750, O60583	C-2k, CDC2L4, PITALRE, TAK, CDC2-related kinase	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
CHK1	CHEK1	O14757	CHEK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
CHK2	CHEK2	O96017	CDS1, HuCds1, PP1425, RAD53, bA444G7	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CHK2(I157T)	CHEK2 (I157T)	O96017	CDS1, HuCds1, PP1425, RAD53, bA444G7	HotSpot^™		Protein kinase	Mutant Panel
CIT 1-450	CIT	O14578	STK2, STK21, KIAA0949, DRIK, CTRO, STK21/CIT, CIT		³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
CK1a1	CSNK1A1	P48729	CK1, HLCDGP1, PRO2975, CK1-alpha1, CK1alpha1, CK1a1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
CK1a1 (E42C)	CK1a1 (E42C)	P48729	CKI-alpha, CK1, KC1A, CSNK1A1	HotSpot^™		Protein kinase	Mutant Panel
CK1a1 (I35C)	CK1a1 (I35C)	P48729	CKI-alpha, CK1, KC1A, CSNK1A1	HotSpot^™		Protein kinase	Mutant Panel
CK1a1L	CSNK1A1L	Q8N752	CK1-alpha1 like	HotSpot^™		Protein kinase	Wild Type Panel
CK1d	CSNK1D	P48730	HCKID, CK1-delta, CK1d, CK1delta	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CK1epsilon	CSNK1E	P49674	CKIe, HCKIE, MGC10398, CK1-epsilon	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CK1epsilon (R178C)	CSNK1E (R178C)	P49674	CKIe, HCKIE, MGC10398, CK1-epsilon	HotSpot^™		Protein kinase	Mutant Panel
CK1g1	CSNK1G1	Q9HCP0	CK1-gamma1, CK1gamma1, CK1g1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
CK1g2	CSNK1G2	P78368	CK1g2, CK1-gamma2, CK1gamma2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CK1g3	CSNK1G3	Q9Y6M4	CK1-gamma3, CK1gamma3	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CK2a	CSNK2A1	P68400	CKII, CK2A1, CK2-alpha1, CK2alpha1, CK2a	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
CK2a2	CSNK2A2	P19784	CK2-alpha2, CK2alpha2, CK2a2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
c-KIT	KIT	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
c-KIT (A829P)	KIT (A829P)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-KIT (d557-558)	KIT (d557-558)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™		Protein kinase	Mutant Panel
c-KIT (d557-558/Y823D)	KIT (d557-558/Y823D)	P10721	C-Kit, PBT, CD117, SCFR	HotSpot^™		Protein kinase	Mutant Panel
c-KIT (D816E)	KIT (D816E)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-KIT (D816F)	KIT (D816F)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™		Protein kinase	Mutant Panel
c-KIT (D816H)	KIT (D816H)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™		Protein kinase	Mutant Panel
c-KIT (D816I)	KIT (D816I)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™		Protein kinase	Mutant Panel
c-KIT (D816V)	KIT (D816V)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-KIT (D816Y)	KIT (D816Y)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™		Protein kinase	Mutant Panel
c-KIT (D820E)	KIT (D820E)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™		Protein kinase	Mutant Panel
c-KIT (D820Y)	KIT (D820Y)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™		Protein kinase	Mutant Panel
c-KIT (K642E)	KIT (K642E)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpotb		Protein kinase
c-KIT (N822K)	KIT (N822K)	P10721	Mast/stem cell growth factor receptor, Proto-oncogene tyrosine-protein kinase c-kit	HotSpot^™		Protein kinase	Mutant Panel
c-KIT (T670I)	KIT (T670I)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-KIT (V559A)	KIT (V559A)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™		Protein kinase	Mutant Panel
c-KIT (V559D)	KIT (V559D)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-KIT (V559D/T670I)	KIT (V559D/T670I)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-KIT (V559D/V654A)	KIT (V559D/V654A)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-KIT (V560G)	KIT (V560G)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-KIT (V560G/D816V)	KIT (V560G/D816V)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™		Protein kinase	Mutant Panel
c-KIT (V560G/N822K)	KIT (V560G/N822K)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™		Protein kinase	Mutant Panel
c-KIT (V654A)	KIT (V654A)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-KIT (Y823D)	KIT (Y823D)	P10721	C-Kit, PBT, CD117, SCFR,	HotSpot^™		Protein kinase	Mutant Panel
CLK1	CLK1	P49759	CLK, CLK/STY	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CLK2	CLK2	P49760	MGC61500, hCLK2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
CLK3	CLK3	P49761	PHCLK3, PHCLK3/152, CDc-like kinase 3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
CLK4	CLK4	Q9HAZ1	DKFZp686A20267, CDc-like kinase 4	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CLK4 (I363V)	CLK4 (I363V)	Q9HAZ1	Dual specificity protein kinase CLK4, CDC-like kinase 4	HotSpot^™		Protein kinase	Mutant Panel
c-MER	MERTK	Q12866	MER, MER-PEN, RP38, c-MER	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
c-MER (A708S)	MERTK (A708S)	Q12866	MER, MER-PEN, RP38, c-MER	HotSpot^™		Protein kinase	Mutant Panel
c-MET	MET	P08581	c-MET, HGFR, RCCP2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
c-MET (D1213H)	MET (D1213H)	P08581	c-Met, HGFR, MET	HotSpot^™		Protein kinase	Mutant Panel
c-MET (D1228A)	MET (D1228A)	P08581	c-MET, HGFR, RCCP2	HotSpot^™		Protein kinase	Mutant Panel
c-MET (D1228G)	MET (D1228G)	P08581	c-MET, HGFR, RCCP2	HotSpot^™		Protein kinase	Mutant Panel
c-MET (D1228H)	MET (D1228H)	P08581	c-MET, HGFR, RCCP2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-MET (D1228N)	MET (D1228N)	P08581	c-MET, HGFR, RCCP2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-MET (D1228V)	MET (D1228V)	P08581	c-MET, HGFR, RCCP2	HotSpot^™		Protein kinase	Mutant Panel
c-MET (D1228Y)	MET (D1228Y)	P08581	c-MET, HGFR, RCCP2	HotSpot^™		Protein kinase	Mutant Panel
c-MET (DelEx14)	MET (DelEx14)	P08581	c-Met, HGFR, MET	HotSpot^™		Protein kinase	Mutant Panel
c-MET (F1200I)	MET (F1200I)	P08581	c-MET, HGFR, RCCP2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-MET (G1163R)	MET (G1163R)	P08581	c-MET, HGFR, RCCP2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-MET (H1094L)	MET (H1094L)	P08581	c-MET, HGFR, RCCP2	HotSpot^™		Protein kinase	Mutant Panel
c-MET (H1094Y)	MET (H1094Y)	P08581	c-MET, HGFR, RCCP2	HotSpot^™		Protein kinase	Mutant Panel
c-MET (K1244R)	MET (K1244R)	P08581	c-MET, HGFR, RCCP2	HotSpot^™		Protein kinase	Mutant Panel
c-MET (L1195F)	MET (L1195F)	P08581	c-MET, HGFR, RCCP2	HotSpot^™		Protein kinase	Mutant Panel
c-MET (L1195V)	MET (L1195V)	P08581	c-MET, HGFR, RCCP2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-MET (M1250I)	MET (M1250I)	P08581	c-MET, HGFR, RCCP2	HotSpot^™		Protein kinase	Mutant Panel
c-MET (M1250T)	MET (M1250T)	P08581	c-MET, HGFR, RCCP2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-MET (P991S)	MET (P991S)	P08581	c-MET, HGFR, RCCP2	HotSpot^™		Protein kinase	Mutant Panel
c-MET (R1227K)	MET (R1227K)	P08581	c-Met, HGFR, MET	HotSpot^™		Protein kinase	Mutant Panel
c-MET (R970C)	MET (R970C)	P08581	c-Met, HGFR, MET	HotSpot^™		Protein kinase	Mutant Panel
c-MET (T1173I)	MET (T1173I)	P08581	c-MET, HGFR, RCCP2	HotSpot^™		Protein kinase	Mutant Panel
c-MET (T992I)	MET (T992I)	P08581	c-MET, HGFR, RCCP2	HotSpot^™		Protein kinase	Mutant Panel
c-MET (V1092I)	MET (V1092I)	P08581	c-MET, HGFR, RCCP2	HotSpot^™		Protein kinase	Mutant Panel
c-MET (Y1230A)	MET (Y1230A)	P08581	c-MET, HGFR, RCCP2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-MET (Y1230C)	MET (Y1230C)	P08581	c-MET, HGFR, RCCP2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-MET (Y1230D)	MET (Y1230D)	P08581	c-MET, HGFR, RCCP2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-MET (Y1230H)	MET (Y1230H)	P08581	c-MET, HGFR, RCCP2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-MET (Y1230S)	MET (Y1230S)	P08581	c-MET, HGFR, RCCP2	HotSpot^™		Protein kinase	Mutant Panel
c-MET (Y1235D)	MET (Y1235D)	P08581	c-MET, HGFR, RCCP2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
c-MET-KIF5B (Kex24Mex14)	MET-KIF5B	P33176, P08581	c-MET, HGFR, RCCP2, KIF5B-MET	HotSpot^™		Protein kinase	Mutant Panel
c-MET-TFG (Tex5Mex15)	MET-TFG	Q92734, P08581	c-MET, HGFR, RCCP2, TGF-MET	HotSpot^™		Protein kinase	Mutant Panel
COT1/MAP3K8	MAP3K8	P41279	COT1, EST, ESTF, TPL2, Tpl-2, COT	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
CSK	CSK	P41240	CSK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
c-SRC	SRC	P12931	ASV, SRC1, c-SRC, p60-Src	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
c-SRC (T341M)	SRC (T341M)	P12931	ASV, SRC1, c-SRC, p60-Src	HotSpot^™		Protein kinase	Mutant Panel
c-SRC (Y530F)	SRC (Y530F)	P12931	ASV, SRC1, c-SRC, p60-Src	HotSpot^™		Protein kinase	Mutant Panel
c-SRC N1	SRC	P12931	ASV, SRC1, c-SRC, p60-Src	HotSpot^™		Protein kinase	Wild Type Panel
CTK/MATK	MATK	P42679	CHK, CTK, DKFZp434N1212, HHYLTK, HYL, Lsk, MGC1708, MGC2101	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
DAPK1	DAPK1	P53355	DAPK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
DAPK2	DAPK2	Q9UIK4	DRP-1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
DCAMKL1	DCLK1	O15075	DCLK, KIAA0369	HotSpot^™		Protein kinase	Wild Type Panel, Diversify Panel
DCAMKL2	DCLK2	Q8N568	DCDC3, DCK2, MGC45428, KIAA0369	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel, Diversify Panel
DCAMKL3	DCLK3	Q9C098	Serine/threonine-protein kinase DCLK3, Doublecortin domain-containing protein 3C, Doublecortin-like and CAM kinase-like 3, Doublecortin-like kinase 3, DCLK3, DCDC3C, KIAA1765	HotSpot^™		Protein kinase	Wild Type Panel
DCK	DCK	P27707	dCK	ADP-Glo		Small molecule
DDR1	DDR1	Q08345	CAK, CD167, DDR, EDDR1, MCK10, NEP	HotSpot^™		Protein kinase	Wild Type Panel, Tyrosine Panel
DDR2	DDR2	Q16832	MIG20a, NTRKR3, TKT, TYRO10	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
DDR2 (N456S)	DDR2 (N456S)	Q16832	MIG20a, NTRKR3, TKT, TYRO10	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
DDR2 (T654M)	DDR2 (T654M)	Q16832	MIG20a, NTRKR3, TKT, TYRO10	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
DGKA	DGKA	P23743	DAGK1, DAGK, DGK-alpha	ADP-Glo		Lipid kinase	DGK Panel
DGKB	DGKB	Q9Y6T7	DAGK2, KIAA0718, DGK-beta	ADP-Glo		Lipid kinase	DGK Panel
DGKD	DGKD	Q16760	DGK-delta, KIAA0145	ADP-Glo		Lipid kinase	DGK Panel
DGKE	DGKE	P52429	DAGK5, DGK-epsilon	ADP-Glo		Lipid kinase	DGK Panel
DGKG	DGKG	P49619	DAGK3, DGK-gamma	ADP-Glo		Lipid kinase	DGK Panel
DGKH	DGKH	Q86XP1	DGK-eta	ADP-Glo		Lipid kinase	DGK Panel
DGKI	DGKI	O75912	DGK-iota	ADP-Glo		Lipid kinase	DGK Panel
DGKK	DGKK	Q5KSL6	DGK-kappa	ADP-Glo		Lipid kinase	DGK Panel
DGKQ	DGKQ	P52824	DAGK4, DGK-theta	ADP-Glo		Lipid kinase	DGK Panel
DGKZ	DGKZ	Q13574	DAGK6, DGK-zeta	ADP-Glo		Lipid kinase	DGK Panel
DLK/MAP3K12	MAP3K12	Q12852	DLK	HotSpotb		Protein kinase
DMPK	DMPK	Q09013	DMPK1, DM, DM1, DM1PK, DMK	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
DMPK2/CDC42BPG	CDC42BPG	Q6DT37	DMPK2, HSMDPKIN, KAPPA-200,	HotSpot^™		Protein kinase	Wild Type Panel
DNA-PK	PRKDC	P78527	DNPK1, HYRC, p350, DNAPK, DNA-PK	HotSpot^™	³³PanQinase^™	Protein kinase	Atypical Panel	Wild Type Panel
DRAK1/STK17A	STK17A	Q9UEE5	DRAK1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
DYRK1/DYRK1A	DYRK1A	Q13627	DYRK, DYRK1, HP86, MNB, MNBH	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
DYRK1B	DYRK1B	Q9Y463	MIRK	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
DYRK2	DYRK2	Q92630	DYRK2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
DYRK3	DYRK3	O43781	DYRK5, RED, REDK	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
DYRK4	DYRK4	Q9NR20	DYRK4	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
EEF2K	EEF2K	O00418	HSU93850, MGC45041, eEF-2K	HotSpot^™	³³PanQinase^™	Protein kinase	Atypical Panel	Wild Type Panel
EGFR	EGFR	P00533	ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
EGFR (A763_Y764insFHEA)	EGFR (A763_Y764insFHEA)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (A763_Y764insFQEA)	EGFR (A763_Y764insFQEA)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (A767_S768insTLA)	EGFR (A767_S768insTLA)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (C775S/T790M/L858R)	EGFR (C775S/T790M/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (C797A)	EGFR (C797A)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (C797G/L858R)	EGFR (C797G/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (C797S)	EGFR (C797S)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (C797S/L858R)	EGFR (C797S/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (d746)	EGFR (d746)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (d746-750)	EGFR (d746-750)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (d746-750/C775S /T790M /L858R)	EGFR (d746-750/C775S/T790M/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (d746-750/C797A)	EGFR (d746-750/C797A)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (d746-750/C797S)	EGFR (d746-750/C797S)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (d746-750/G724S)	EGFR (d746-750/G724S)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (d746-750/S768I)	EGFR (d746-750/S768I)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (d746-750/T790M)	EGFR (d746-750/T790M)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (d746-750/T790M/C797S)	EGFR (d746-750/T790M/C797S)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (d746-750/T790M/C797S/L858R)	EGFR (d746-750/T790M/C797S/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (d746-750/T790M/L792F)	EGFR (d746-750/T790M/L792F)	P00533	EGFR, ERBB1, HER1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (d746-750/T790M/L792H)	EGFR (d746-750/T790M/L792H)	P00533	EGFR, ERBB1, HER1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (d746-750/T790M/L798I)	EGFR (d746-750/T790M/L798I)	P00533	EGFR, ERBB1, HER1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (d746-750/T790M/L858R)	EGFR (d746-750/T790M/L858R)	P00533	EGFR, ERBB1, HER1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (d747-749)	EGFR (d747-749)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (d747-749/A750P)	EGFR (d747-749/A750P)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (d747-752/P753S)	EGFR (d747-752/P753S)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (d752-759)	EGFR (d752-759)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (D761Y)	EGFR (D761Y)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (D770_N771insG)	EGFR (D770_N771insG)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (D770_N771insNPG)	EGFR (D770_N771insNPG)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (D770_N771insNPG/T790M)	EGFR (D770_N771insNPG/T790M)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (D770GY)	EGFR (D770GY)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (G719C)	EGFR (G719C)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (G719D)	EGFR (G719D)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (G719S)	EGFR (G719S)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (K716A)	EGFR (K716A)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (K716A/C797S/L858R)	EGFR (K716A/C797S/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (K716A/T790M/C797S/L858R)	EGFR (K716A/T790M/C797S/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (K716Q/L718Q)	EGFR (K716Q/L718Q)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (K728A)	EGFR (K728A)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (K728A/T790M/C797S/L858R)	EGFR (K728A/T790M/C797S/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (L718Q)	EGFR (L718Q)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (L747S)	EGFR (L747S)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (L792F)	EGFR (L792F)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (L792F/L858R)	EGFR (L792F/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (L792H)	EGFR (L792H)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (L792H/C797S/L858R)	EGFR (L792H/C797S/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (L792H/L858R)	EGFR (L792H/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (L858R)	EGFR (L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (L858R/T790M)	EGFR (T790M/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (L861Q)	EGFR (L861Q)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (N771_P772insH)	EGFR (N771_P772insH)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (N771_P772insN)	EGFR (N771_P772insN)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (R999A)	EGFR (R999A)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (S768I)	EGFR (S768I)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (T790M)	EGFR (T790M)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (T790M/C797G/L858R)	EGFR (T790M/C797G/L858R)	P00533	EGFR, ErbB-1, HER1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (T790M/C797S /L858R)	EGFR (T790M/C797S/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
EGFR (T790M/C797S)	EGFR (T790M/C797S)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (T790M/L792F/C797S/L858R)	EGFR (T790M/L792F/C797S/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (T790M/L792F/L858R)	EGFR (T790M/L792F/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (T790M/L792H/C797S/L858R)	EGFR (T790M/L792H/C797S/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (T790M/L792H/L858R)	EGFR (T790M/L792H/L858R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (V769_D770insGE)	EGFR (V769_D770insGE)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EGFR (V948R)	EGFR (V948R)	P00533	EGF-R, ERBB, mENA, ERBB1	HotSpot^™		Protein kinase	Mutant Panel
EIF2AK1/HRI	EIF2AK1	Q9BQI3	HCR, HRI, EIF2AK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Atypical Panel	Wild Type Panel
EIF2AK2/PKR	EIF2AK2	P19525	PKR, PRKR	HotSpot^™	³³PanQinase^™	Protein kinase	Atypical Panel	Wild Type Panel
EIF2AK3/PERK	EIF2AK3	Q9NZJ5	DKFZp781H1925, PEK, PERK, WRS	HotSpot^™	³³PanQinase^™	Protein kinase	Atypical Panel	Wild Type Panel
EIF2AK4/GCN2	EIF2AK4	Q9P2K8	GCN2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Atypical Panel	Wild Type Panel
EML4 ALK	ALK-EML4	Q9UM73	CD246, NBLST3, EML4-ABL		³³PanQinase^™, ADP-Glo	Protein kinase		Mutant Panel
EPHA1	EPHA1	P21709	EPH, EPHT, EPHT1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
EPHA2	EPHA2	P29317	ECK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
EPHA3	EPHA3	P29320	ETK, ETK1, HEKECK, HEK4, TYRO4	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
EPHA4	EPHA4	P54764	HEK8, SEK, TYRO1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
EPHA5	EPHA5	P54756	CEK7, EHK1,HEK7	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
EPHA6	EPHA6	Q9UF33	EHK2, EHK-2, EPA6	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
EPHA7	EPHA7	Q15375	EHK3, HEK11	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
EPHA8	EPHA8	P29322	EEK, HEK3, KIAA1459	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
EPHB1	EPHB1	P54762	ELK, NET, Hek6, EPHT2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
EPHB2	EPHB2	P29323	DRT, ERK, Hek5, EPHT3, Tyro5	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
EPHB3	EPHB3	P54753	ETK2, HEK2, TYRO6	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
EPHB4	EPHB4	P54760	HTK, MYK1, TYRO11	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
ERBB2 (A775_G776insYVMA)	ERBB2 (A775_G776insYVMA)	P04626	NEU, NGL, HER2, TKR1	HotSpot^™		Protein kinase	Mutant Panel
ERBB2 (D769H)	ERBB2 (D769H)	P04626	NEU, NGL, HER2, TKR1	HotSpot^™		Protein kinase	Mutant Panel
ERBB2 (D769Y)	ERBB2 (D769Y)	P04626	NEU, NGL, HER2, TKR1	HotSpot^™		Protein kinase	Mutant Panel
ERBB2 (P1170A)	ERBB2 (P1170A)	P04626	NEU, NGL, HER2, TKR1	HotSpot^™		Protein kinase	Mutant Panel
ERBB2 (P780-Y781insGSP)	ERBB2 (P780-Y781insGSP)	P04626	NEU, NGL, HER2, TKR1	HotSpot^™		Protein kinase	Mutant Panel
ERBB2 (R896C)	ERBB2 (R896C)	P04626	NEU, NGL, HER2, TKR1	HotSpot^™		Protein kinase	Mutant Panel
ERBB2 (V777_G778insCG)	ERBB2 (V777_G778insCG)	P04626	NEU, NGL, HER2, TKR1	HotSpot^™		Protein kinase	Mutant Panel
ERBB2 (V777L)	ERBB2 (V777L)	P04626	NEU, NGL, HER2, TKR1	HotSpot^™		Protein kinase	Mutant Panel
ERBB2 (V956R)	ERBB2 (V956R)	P04626	NEU, NGL, HER2, TKR1	HotSpot^™		Protein kinase	Mutant Panel
ERBB2 775YVMA776	ERBB2 (775YVMA776)	P04626	NEU, NGL, HER2, TKR1		³³PanQinase^™, ADP-Glo	Protein kinase		Mutant Panel
ERBB2/HER2	ERBB2	P04626	NEU, NGL, HER2, TKR1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
ERBB4/HER4	ERBB4	Q15303	HER4	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
ERK1/MAPK3	MAPK3	P27361	ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
ERK2/MAPK1	MAPK1	P28482	ERK2, ERT1, P42MAPK, PRKM1,	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
ERK5	MAPK7 (aa5-397)	Q13164	BMK1, ERK4, PRKM7		³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
ERK5/MAPK7 CD	MAPK7 (CD)	Q13164	BMK1, PRKM7	HotSpot^™		Protein kinase
ERK5/MAPK7 FL	MAPK7	Q13164	BMK1, PRKM7	HotSpot^™		Protein kinase	Wild Type Panel
ERK7/MAPK15	MAPK15	Q8TD08	ERK8	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
ERN1 (R727A)	ERN1 (R727A)	O75460	IRE1	HotSpot^™		Protein kinase	Mutant Panel
ERN1 (R728A)	ERN1 (R728A)	O75460	IRE1	HotSpot^™		Protein kinase	Mutant Panel
ERN1/IRE1	ERN1	O75460	IRE1P, IRE1, ERN1, FLJ30999	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
ERN1/IRE1 (R727A/R728A)	ERN1/IRE1 (R727A/R728A)	O75460	IRE1	HotSpot^™		Protein kinase	Mutant Panel
ERN2/IRE2	ERN2	Q76MJ5	IRE2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
FAK aa411-686	PTK2 (aa411-686)	Q05397	FAK, FADK		³³PanQinase^™, ADP-Glo	Protein kinase
FAK/PTK2	PTK2	Q05397	FAK, FADK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
FER	FER	P16591	TYK3, c-FER, p94-FER	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
FES/FPS	FES	P07332	FPS	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
FGFR1	FGFR1	P11362	H2, H3, H4, H5, CEK, FLG, FLT2, KAL2, BFGFR, C-FGR, N-SAM	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
FGFR1 (W666R)	FGFR1 (W666R)	P11362	FGFR-1, bFGF-R, FLT2, c-fgr	HotSpot^™		Protein kinase	Mutant Panel
FGFR1(V561M)	FGFR1 (V561M)	P11362	H2, H3, H4, H5, CEK, FLG, FLT2, KAL2, BFGFR, C-FGR, N-SAM	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
FGFR1OP- FGFR1	CEP43-FGFR1	O95684, P11362	FOP, CEP43, FGFR1-FGFR1OP	HotSpot^™		Protein kinase	Mutant Panel
FGFR2	FGFR2	P21802	BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
FGFR2 (C491A)	FGFR2 (C491A)	P21802	BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (C491A/V564I)	FGFR2 (C491A/V564I)	P21802	Fibroblast growth factor receptor 2 [Precursor], Keratinocyte growth factor receptor 2	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (C491A/V564L)	FGFR2 (C491A/V564L)	P21802	Fibroblast growth factor receptor 2 [Precursor], Keratinocyte growth factor receptor 2	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (C491F)	FGFR2 (C491F)	P21802	BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (C491S)	FGFR2 (C491S)	P21802	BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (C491S/V564L)	FGFR2 (C491S/V564L)	P21802	Fibroblast growth factor receptor 2 [Precursor], Keratinocyte growth factor receptor 2	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (E565A)	FGFR2 (E565A)	P21802	Fibroblast growth factor receptor 2 [Precursor], Keratinocyte growth factor receptor 2	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (E565G)	FGFR2 (E565G)	P21802	BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (K526E)	FGFR2 (K526E)	P21802	BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (K641R)	FGFR2 (K641R)	P21802	BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (K659N)	FGFR2 (K659N)	P21802	BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (M420I)	FGFR2 (M420I)	P21802	Fibroblast growth factor receptor 2 [Precursor], Keratinocyte growth factor receptor 2	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (N549H)	FGFR2 (N549H)	P21802	BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (N549K)	FGFR2 (N549K)	P21802	Fibroblast growth factor receptor 2 [Precursor], Keratinocyte growth factor receptor 2	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (R612T)	FGFR2 (R612T)	P21802	BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (V564F)	FGFR2 (V564F)	P21802	BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (V564I)	FGFR2 (V564I)	P21802	Fibroblast growth factor receptor 2 [Precursor], Keratinocyte growth factor receptor 2	HotSpot^™		Protein kinase	Mutant Panel
FGFR2 (V564L)	FGFR2 (V564L)	P21802	Fibroblast growth factor receptor 2 [Precursor], Keratinocyte growth factor receptor 2	HotSpot^™		Protein kinase	Mutant Panel
FGFR3	FGFR3	P22607	ACH, CD333, CEK2, HSFGFR3EX, JTK4	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
FGFR3 (G697C)	FGFR3 (G697C)	P22607	ACH, CD333, CEK2, HSFGFR3EX, JTK4	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
FGFR3 (K650E)	FGFR3 (K650E)	P22607	ACH, CD333, CEK2, HSFGFR3EX, JTK4	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
FGFR3 (K650M)	FGFR3 (K650M)	P22607	ACH, CD333, CEK2, HSFGFR3EX, JTK4	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
FGFR3 (K650Q)	FGFR3 (K650Q)	P22607	ACH, CD333, CEK2, HSFGFR3EX, JTK4	HotSpot^™		Protein kinase	Mutant Panel
FGFR3 (V555M)	FGFR3 (V555M)	P22607	ACH, CD333, CEK2, HSFGFR3EX, JTK4	HotSpot^™		Protein kinase	Mutant Panel
FGFR4	FGFR4	P22455	TKF, JTK2, MGC20292	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
FGFR4 (N535K)	FGFR4 (N535K)	P22455	TKF, JTK2, MGC20292	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel
FGFR4 (V550E)	FGFR4 (V550E)	P22455	TKF, JTK2, MGC20292	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel
FGFR4 (V550L)	FGFR4 (V550L)	P22455	TKF, JTK2, MGC20292	HotSpot^™		Protein kinase	Mutant Panel
FGFR4 (V550M)	FGFR4 (V550M)	P22455	TKF, JTK2, MGC20292	HotSpot^™		Protein kinase	Mutant Panel
FGR	FGR	P09769	SRC2, c-fgr, p55c-fgr	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
FLT1/VEGFR1	FLT1	P17948	FLT, VEGFR1, FLT1, VEGF-R1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
FLT3	FLT3	P36888	FLK2, STK1, CD135	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
FLT3 (D835H)	FLT3 (D835H)	P36888	FLK2, STK1, CD135	HotSpot^™		Protein kinase	Mutant Panel
FLT3 (D835V)	FLT3 (D835V)	P36888	FLK2, STK1, CD135	HotSpot^™		Protein kinase	Mutant Panel
FLT3 (D835Y)	FLT3 (D835Y)	P36888	FLK2, STK1, CD135	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
FLT3 (F594_R595insR)	FLT3 (F594_R595insR)	P36888	FLK2, STK1, CD135	HotSpot^™		Protein kinase	Mutant Panel
FLT3 (F594_R595insREY)	FLT3 (F594_R595insREY)	P36888	FLK2, STK1, CD135	HotSpot^™		Protein kinase	Mutant Panel
FLT3 (F691L)	FLT3 (F691L)	P36888	FLK2, STK1, CD135	HotSpot^™		Protein kinase	Mutant Panel
FLT3 (F691L/D835Y)	FLT3 (F691L/D835Y)	P36888	FLK2, STK1, CD135	HotSpot^™		Protein kinase	Mutant Panel
FLT3 (ITD)	FLT3 (ITD)	P36888	FLK2, STK1, CD135	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
FLT3 (ITD)-NPOS	FLT3 (ITD)-NPOS	P36888	FLK2, STK1, CD135	HotSpot^™		Protein kinase	Mutant Panel
FLT3 (ITD)-W51	FLT3 (ITD)-W51	P36888	FLK2, STK1, CD135	HotSpot^™		Protein kinase	Mutant Panel
FLT3 (R595_E596insEY)	FLT3 (R595_E596insEY)	P36888	FLK2, STK1, CD135	HotSpot^™		Protein kinase	Mutant Panel
FLT3 (Y591_V592insVDFREYEYD)	FLT3 (Y591_V592insVDFREYEYD)	P36888	FLK2, STK1, CD135	HotSpot^™		Protein kinase	Mutant Panel
FLT3 (Y591-V592insVDFREYEYD/D835Y)	FLT3 (Y591-V592insVDFREYEYD/D835Y)	P36888	FLK2, STK1, CD135	HotSpot^™		Protein kinase	Mutant Panel
FLT3 (Y591-V592insVDFREYEYD/F691L)	FLT3 (Y591-V592insVDFREYEYD/F691L)	P36888	FLK2, STK1, CD135	HotSpot^™		Protein kinase	Mutant Panel
FLT4/VEGFR3	FLT4	P35916	VEGFR3, PCL, VEGF-R3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
FMS	CSF1R	P07333	C-FMS, CD115, CSF-1-R, CSFR, FIM2, FMS, CSF1R	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
FRK/PTK5	FRK	P42685	PTK5, GTK, RAK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
FYN	FYN	P06241	SLK, SYN, p59-Fyn	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
FYN (Y531F)	FYN (Y531F)	P06241	SLK, SYN, p59-Fyn	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
FYN-A	FYN	P06241	SLK, SYN, p59-Fyn	HotSpot^™		Protein kinase	Wild Type Panel
GAK	GAK	O14976	Cyclin-G-associated kinase, auxilin2, DNAJC26, MGC99654	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
GCK/MAP4K2	MAP4K2	Q12851	BL44, GCK, RAB8IP	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
GLK/MAP4K3	MAP4K3	Q8IVH8	GLK, MAPKKKK3, RAB8IPL1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
GRK1	GRK1	Q15835	RHOK, GPRK1, RK	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
GRK2	GRK2	P25098	ADRBK1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
GRK3	GRK3	P35626	ADRBK2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
GRK4	GRK4	P32298	GPRK2L, GPRK4, GRK4a, IT11	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
GRK5	GRK5	P34947	GPRK5	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
GRK6	GRK6	P43250	GPRK6, FLJ32135	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
GRK7	GRK7	Q8WTQ7	GPRK7	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
GSK3a	GSK3A	P49840	GSK3alpha, GSK3a	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
GSK3b	GSK3B	P49841	GSK3beta, GSK3b	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
GSK3b (C199A)	GSK3b (C199A)	P49841	Glycogen synthase kinase-3 beta	HotSpot^™		Protein kinase	Mutant Panel
Haspin	GSG2	Q8TF76	GSG2, Haspin	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
HCK	HCK	P08631	JTK9	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
HGK/MAP4K4	MAP4K4	O95819	HGK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
HIPK1	HIPK1	Q86Z02	KIAA0630, MGC26642, MGC33446, Myak, Nbak2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
HIPK2	HIPK2	Q9H2X6	PRO0593	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
HIPK3	HIPK3	Q9H422	ANPK, DYRK6, FIST, FIST3, PKY, YAK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
HIPK4	HIPK4	Q8NE63	FLJ32818	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
HPK1/MAP4K1	MAP4K1	Q92918	HPK1, MAP4K1, HPK1/MAP4K1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
HUNK	HUNK	P57058	MAKV, B19	HotSpot^™		Protein kinase	Wild Type Panel
IGF1R	IGF1R	P08069	JTK13, IGFR, CD221	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
IKKa/CHUK	CHUK	O15111	IKBKA, IKK1, IKKA, NFKBIKA, TCF16, IKK-alpha, IKKalpha, IKKa	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
IKKb/IKBKB	IKBKB	O14920	IKK2, IKKB, NFKBIKB, IKK-beta, IKKbeta	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
IKKe/IKBKE	IKBKE	Q14164	IKKI, IKK-i, KIAA0151, IKK-epsilon, IKKepsilon	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
IR	INSR	P06213	IR	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
IRAK1	IRAK1	P51617	Pelle	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
IRAK2	IRAK2	O43187	Interleukin-1 receptor-associated kinase-like 2	HotSpot^™		Protein kinase
IRAK3	IRAK3	Q9Y616	IRAK-M	Probe-displacement		Protein kinase
IRAK4	IRAK4	Q9NWZ3	REN64	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
IRAK4 aa104-460 (untagged)	IRAK4 (aa104-460) untagged	Q9NWZ3	REN64		³³PanQinase^™, ADP-Glo	Protein kinase
IRR/INSRR	INSRR	P14616	IRR	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
ITK	ITK	Q08881	EMT 2, LYK 2, PSCTK2 2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
JAK1	JAK1 (aa866-1154)	P23458	JAK1A, JAK1B, JTK3	HotSpot^™		Protein kinase	Wild Type Panel, Tyrosine Panel
JAK1 aa850-1154	JAK1 (aa850-1154)	P23458	JAK1A, JAK1B, JTK3		³³PanQinase^™, ADP-Glo	Protein kinase
JAK1 JH2	JAK1 JH2	P23458	JAK1A, JAK1B, JTK3	Probe-displacement		Protein kinase
JAK1 S729C	JAK1 (S729C)	P23458	JAK1A, JAK1B, JTK3		³³PanQinase^™, ADP-Glo	Protein kinase		Mutant Panel
JAK2	JAK2	O60674	JAK2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
JAK2 (V617F)	JAK2 (V617F)	O60674	JAK2	HotSpot^™		Protein kinase	Mutant Panel
JAK2 JH1&2	JAK2 (JH1&2)	O60674	JAK2	HotSpot^™	³³PanQinase^™	Protein kinase
JAK2 JH2	JAK2 JH2	O60674	JAK2	Probe-displacement		Protein kinase
JAK3	JAK3	P52333	JAKL, L-JAK, LJAK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
JAK3 JH1 & JH2	JAK3	P52333	JAKL, L-JAK, LJAK	HotSpot^™		Protein kinase
JNK1	MAPK8	P45983-2	PRKM8, SAPK1, JNK1-alpha1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
JNK2	MAPK9	P45984-1	PRKM9, SAPK, p54a, JNK-alpha2, JNK2A, JNK2B	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
JNK3	MAPK10	P53779	JNK3A, PRKM10, p493F12	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
KDR/VEGFR2	KDR	P35968	VEGFR2, FLK1, VEGF-R2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
KHS/MAP4K5	MAP4K5	Q9Y4K4	KHS1, GCKR, KHS, MAPKKKK5	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
KSR1	KSR1	Q8IVT5	Kinase suppressor of Ras 1	HotSpotb		Protein kinase
KSR1 (A635F)	KSR1 (A635F)	Q8IVT5	Kinase suppressor of Ras 1	HotSpotb		Protein kinase
KSR1 (L639F)	KSR1 (L639F)	Q8IVT5	Kinase suppressor of Ras 1	HotSpotb		Protein kinase
KSR2	KSR2	Q6VAB6	Kinase suppressor of Ras 2	HotSpotb		Protein kinase
KSR2 (R676S)	KSR2 (R676S)	Q6VAB6	Kinase suppressor of Ras 2	HotSpotb		Protein kinase
LATS1	LATS1	O95835	WARTS, wts	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
LATS2	LATS2	Q9NRM7	FLJ13161, LATS	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
LCK	LCK	P06239	LCK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
LCK2/ICK	CILK1	Q9UPZ9	LCK2, ICK, MRK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
LIMK1	LIMK1	P53667	LIMK	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
LIMK2	LIMK2	P53671	LIMK2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
LKB1	STK11	Q15831	LKB1, PJS	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
LOK/STK10	STK10	O94804	LOK, PRO2729	HotSpot^™		Protein kinase	Wild Type Panel, Diversify Panel
LRRK2	LRRK2	Q5S007	PARK8, ROCO2, FLJ45829, DKFZp434H2111	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
LRRK2 (G2019S)	LRRK2 (G2019S)	Q5S007	PARK8, ROCO2, FLJ45829, DKFZp434H2111	HotSpot^™	³³PanQinase^™	Protein kinase	Mutant Panel	Mutant Panel
LRRK2 (I2020T)	LRRK2 (I2020T)	Q5S007	PARK8, ROCO2, FLJ45829, DKFZp434H2111	HotSpot^™	³³PanQinase^™	Protein kinase	Mutant Panel	Mutant Panel
LRRK2 (R1441C)	LRRK2 (R1441C)	Q5S007	PARK8, ROCO2, FLJ45829, DKFZp434H2111	HotSpot^™	³³PanQinase^™	Protein kinase	Mutant Panel	Mutant Panel
LYN	LYN	P07948	JTK8	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
LYNB	LYN (d23-43)	P07948-2	JTK8	HotSpot^™		Protein kinase	Wild Type Panel, Tyrosine Panel
MAK	MAK	P20794	MAK	HotSpot^™		Protein kinase	Wild Type Panel
MAPKAPK2	MAPKAPK2	P49137	MAPKAPK2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MAPKAPK3	MAPKAPK3	Q16644	3PK, MAPKAP, MAPKAP3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MAPKAPK5/PRAK	MAPKAPK5	Q8IW41	PRAK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MARK1	MARK1	Q9P0L2	KIAA1477	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MARK2/PAR-1Ba	MARK2	Q7KZI7-4	EMK1, MGC99619, PAR-1Ba, ELKL	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
MARK3	MARK3	P27448	CTAK1, KP78, PAR1A	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MARK4	MARK4	Q96L34	KIAA1860, MARKL1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
MAST3	MAST3	O60307	Microtubule-associated serine/threonine-protein kinase 3, KIAA0561	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel
MASTL	MASTL	Q96GX5	GLW, GREATWALL, GWL, hGWL, THC2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel, Diversify Panel
mDGKA	DGKA Mouse	O88673	DAG kinase alpha, 80 kDa diacylglycerol kinase, DAGK1	ADP-Glo		Lipid kinase
mDGKZ	DGKZ Mouse	Q80UP3	Diacylglycerol kinase zeta, DAG kinase zeta, Dgkz	ADP-Glo		Lipid kinase
MEK1	MAP2K1	Q02750	MAPKK1, MKK1, PRKMK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
MEK1 (P124L)	MAP2K1 (P124L)	Q02750	MAPKK1, MKK1, PRKMK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel
MEK1 F53L	MAP2K1 (F53L)	Q02750	MAPKK1, MKK1, PRKMK1		³³PanQinase^™, ADP-Glo	Protein kinase		Mutant Panel
MEK1 SESE	MAP2K1 (S218E/S222E)	Q02750	MAPKK1, MKK1, PRKMK1		³³PanQinase^™, ADP-Glo	Protein kinase
MEK2	MAP2K2	P36507	MAPKK2, MKK2, PRKMK2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
MEK3	MAP2K3	P46734	MAPKK3, MEK3, MKK3, PRKMK3, SAPK kinase 2, SAPKK-2, SAPKK2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MEK5	MAP2K5	Q13163	MAPKK5, MKK5, PRKMK5	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MEKK1	MAP3K1	Q13233	MAPKKK1, MEKK, MEKK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
MEKK2	MAP3K2	Q9Y2U5	MAPKKK2, MEKK2B	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MEKK3	MAP3K3	Q99759	MAPKKK3, MEK kinase3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MEKK6	MAP3K6	O95382	ASK2, MAPKKK6	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MELK	MELK	Q14680	KIAA0175, PK38	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MELK (T460M)	MELK (T460M)	Q14680	KIAA0175, PK38	HotSpot^™		Protein kinase	Mutant Panel
MINK/MINK1	MINK1	Q8N4C8	B55, YSK2, MAP4K6, ZC3, MINK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MKK4	MAP2K4	P45985	JNKK, JNKK1, MAPKK4, MEK4, PRKMK4, SEK, SERK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MKK6	MAP2K6	P52564	MAPKK6, MEK6, PRKMK6, SAPKK3	HotSpot^™		Protein kinase	Wild Type Panel
MKK6 SDTD	MAP2K6 (S207D/T211D)	P52564	MAPKK6, MEK6, PRKMK6, SAPKK3		³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
MKK7	MAP2K7	O14733	MAPKK7, MEK7, PRKMK7	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MLCK/MYLK	MYLK	Q15746	smMLCK, FLJ12216, KRP, MLCK, MLCK108, MLCK210	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
MLCK2/MYLK2	MYLK2	Q9H1R3	KMLC, skMLCK, MLCK2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MLK1/MAP3K9	MAP3K9	P80192	MLK1, PRKE1, MEKK9	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
MLK2/MAP3K10	MAP3K10	Q02779	MLK2, MST, MEKK10	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MLK3/MAP3K11	MAP3K11	Q16584	MGC17114, MLK-3, PTK1, SPRK, MLK3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MLK4	MAP3K21	Q5TCX8	KIAA1804	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MNK1	MKNK1	Q9BUB5	MNK1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
MNK2	MKNK2	Q9HBH9	MNK2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
MRCKa/CDC42BPA	CDC42BPA	Q5VT25	MRCK-alpha, MRCKa	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
MRCKb/CDC42BPB	CDC42BPB	Q9Y5S2	MRCK-beta, MRCKb	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MSK1/RPS6KA5	RPS6KA5	O75582	MSK1, RLPK	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
MSK2/RPS6KA4	RPS6KA4	O75676	MSK2, RSK-B	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
MSSK1/STK23	SRPK3	Q9UPE1	MSSK1, MGC102944, STK23	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
MST1/STK4	STK4	Q13043	MST1, KRS2, YSK3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
MST2/STK3	STK3	Q13188	MST2, KRS1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
MST3/STK24	STK24	Q9Y6E0	MST3	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
MST4	STK26	Q9P289	MASK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
mTOR/FRAP1	MTOR	P42345	FRAP1, FRAP, FRAP2, RAFT1, RAPT1	HotSpot^™	³³PanQinase^™	Protein kinase	Atypical Panel	Wild Type Panel
MUSK	MUSK	O15146	MUSK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
MYLK3	MYLK3	Q32MK0	caMLCK, MLCK	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
MYLK4	MYLK4	Q86YV6	Myosin light chain kinase family member 4	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
MYO3A	MYO3A	Q8NEV4	Myosin-IIIa	HotSpot^™		Protein kinase	Wild Type Panel
MYO3b	MYO3B	Q8WXR4	MYO3b	HotSpot^™		Protein kinase	Wild Type Panel
NEK1	NEK1	Q96PY6	KIAA1901, NY-REN-55,	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
NEK11	NEK11	Q8NG66	FLJ23495	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
NEK2	NEK2	P51955	NLK1, HsPK21, HsPK 21	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
NEK3	NEK3	Q8WUN5	HSPK36, MGC29949	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
NEK4	NEK4	P51957	NRK2, STK2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
NEK5	NEK5	Q6P3R8	MGC75495	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
NEK6	NEK6	Q9HC98	SID6-1512	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
NEK7	NEK7	Q8TDX7	NEK7	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
NEK8	NEK8	Q86SG6	NEK8	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
NEK9	NEK9	Q8TD19	DKFZp434D0935, MGC16714, NERCC,	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
NIK/MAP3K14	MAP3K14	Q99558	NIK, FTDCR1B, HS, HSNIK	HotSpotb, ADP-Glo	³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
NIM1	NIM1K	Q8IY84	NIM1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
NLK	NLK	Q9UBE8	NLK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
OSR1/OXSR1	OXSR1	O95747	OSR1, KIAA1101	HotSpot^™		Protein kinase	Wild Type Panel
p38a (T106M)	MAPK14 (T106M)	Q16539	p38-alpha, CSBP, CSBP1, p38alpha, p38a	HotSpot^™		Protein kinase	Mutant Panel
P38a/MAPK14	MAPK14	Q16539	p38-alpha, CSBP, CSBP1, p38alpha, p38a	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
P38b/MAPK11	MAPK11	Q15759	p38-beta, P38BETA2, PRKM11, SAPK2, p38beta, p38b	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
P38d/MAPK13	MAPK13	O15264	p38-delta, PRKM13, SAPK4, p38delta, p38d	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
P38g/MAPK12	MAPK12	P53778	p38-gamma, ERK3, ERK5, ERK6, p38gamma, p38g	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
P70S6K/RPS6KB1	RPS6KB1	P23443	S6K, STK14A, P70S6K	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
P70S6Kb/RPS6KB2	RPS6KB2	Q9UBS0	KLS, P70-beta-1, P70-beta-2, S6K-beta2, S6K2, SRK, p70S6Kb, S6K-beta, S6Kbeta	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
PAK1	PAK1	Q13153	PAKalpha	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PAK2	PAK2	Q13177	PAK65, PAKgamma	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PAK2 (Y443N)	PAK2 (Y443N)	Q13177	PAK-2, PAK65, Gamma-PAK, S6/H4 kinase	HotSpot^™		Protein kinase	Mutant Panel
PAK3	PAK3	O75914	MRX30, OPHN3, PAK3beta, bPAK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PAK4	PAK4	O96013	PAK4	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
PAK5	PAK5	Q9P286	PAK7, PAK5, KIAA1264, MGC26232	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PAK6	PAK6	Q9NQU5	PAK6, PAK5	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PASK	PASK	Q96RG2	DKFZP434O051, DKFZp686P2031, KIAA0135, PASKIN, STK3	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
PBK/TOPK	PBK	Q96KB5	TOPK, SPK, Nori-3, FLJ14385	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PDGFRa	PDGFRA	Q9DE49	PDGFRalpha, PDGFR2, CD140a	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
PDGFRa(D842V)	PDGFRA (D842V)	Q9DE49	PDGFRalpha, PDGFR2, CD140a	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
PDGFRa(G680R)	PDGFRA (G680R)	Q9DE49	PDGFRalpha, PDGFR2, CD140a	HotSpot^™		Protein kinase	Mutant Panel
PDGFRa(T674I)	PDGFRA (T674I)	Q9DE49	PDGFRalpha, PDGFR2, CD140a	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
PDGFRa(V561D)	PDGFRA (V561D)	Q9DE49	PDGFRalpha, PDGFR2, CD140a	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
PDGFRa-FIP1L1	PDGFRA-FIP1L1	Q6UN15, Q9DE49	PDGFRalpha, PDGFR2, CD140a, FIP1L1-PDGFRA	HotSpot^™		Protein kinase	Mutant Panel
PDGFRb	PDGFRB	P09619	PDGFRbeta, JTK12, PDGFR, CD140B, PDGFR1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
PDGFRb-TPM3	PDGFRB-TPM3	P06753, P09619	PDGFRbeta, JTK12, PDGFR, CD140B, PDGFR1, TPM3-PDGFRB	HotSpot^™		Protein kinase	Mutant Panel
PDK1/PDHK1	PDK1	Q15118	PDHK1, Pyruvate dehydrogenase kinase	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Atypical Panel	Wild Type Panel
PDK1/PDPK1	PDPK1	O15530	PDK1, PKB-like, 3-phosphoinositide-dependent protein kinase 1	HotSpot^™		Protein kinase	Wild Type Panel
PDK2/PDHK2	PDK2	Q15119	PDHK2	HotSpot^™		Protein kinase	Atypical Panel
PDK3/PDHK3	PDK3	Q15120	PDHK3	HotSpot^™		Protein kinase	Atypical Panel
PDK4/PDHK4	PDK4	Q16654	PDHK4	HotSpot^™		Protein kinase	Atypical Panel
PDXK	PDXK	O00764	C21orf124, C21orf97, PKH, PNK	ADP-Glo		Small molecule
PEAK1	PEAK1	Q9H792	PEAK1, KIAA2002	HotSpotb		Protein kinase
PHKg1	PHKG1	Q16816	PHKg1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
PHKg2	PHKG2	P15735	PHKg2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
PI3K (p110a(E542K)/p85a)	PIK3CA (E542K)-PIK3R1	P42336, P27986	MGC142161, MGC142163, p110-alpha, PI3K, PI3K-alpha	ADP-Glo	ADP-Glo	Lipid kinase	Lipid Kinase Panel
PI3K (p110a(E545K)/p85a)	PIK3CA (E545K)-PIK3R1	P42336, P27986	MGC142161, MGC142163, p110-alpha, PI3K, PI3K-alpha	ADP-Glo	ADP-Glo	Lipid kinase	Lipid Kinase Panel
PI3K (p110a(H1047R)/p85a)	PIK3CA (H1047R)-PIK3R1	P42336, P27986	MGC142161, MGC142163, p110-alpha, PI3K, PI3K-alpha	ADP-Glo	ADP-Glo	Lipid kinase	Lipid Kinase Panel
PI3K (p110a/p55g)	PI3K (p110a/p55g)	B7ZLY6, Q8N381	PIK3CA, PIK3R3	ADP-Glo		Lipid kinase	Lipid Kinase Panel
PI3K (p110a/p65a)	PIK3CA-PIK3R1/p65a	P42336, P27986	MGC142161, MGC142163, p110-alpha, PI3K, PI3K-alpha	ADP-Glo	ADP-Glo	Lipid kinase	Lipid Kinase Panel	Lipid Kinase Panel
PI3Ka (p110a/p85a)	PIK3CA-PIK3R1	P42336, P27986	MGC142161, MGC142163, p110-alpha, PI3K, PI3K-alpha	ADP-Glo		Lipid kinase	Lipid Kinase Panel, Diversify Panel
PI3Kb (p110b/p85a)	PIK3CB-PIK3R1	P42338, P27986	PI3K, PI3KBETA, PIK3C1, p110-beta	ADP-Glo		Lipid kinase	Lipid Kinase Panel, Diversify Panel
PI3Kb (p110b/p85b)	PI3Kb (p110b/p85b)	P42338, O00459	PIK3CB, PIK3C1	ADP-Glo		Lipid kinase	Lipid Kinase Panel
PI3KC2a	PIK3C2A	O00443	CPK, MGC142218, PI3-K-C2A	ADP-Glo	ADP-Glo	Lipid kinase	Lipid Kinase Panel	Lipid Kinase Panel
PI3KC2B	PI3KC2B	O00750	P3C2B, PIK3C2B, C2-PI3K	ADP-Glo		Lipid kinase	Lipid Kinase Panel
PI3KC2G/PIK3C2G	PI3KC2G/PIK3C2G	B7ZLY6	PI3K-C2GAMMA, PI3K-C2-gamma	ADP-Glo		Lipid kinase	Lipid Kinase Panel
PI3KC3	PIK3C3	Q8NEB9	MGC61518, PI3-kinase type 3, PI3K type 3, Vps34	ADP-Glo	ADP-Glo	Lipid kinase	Lipid Kinase Panel	Lipid Kinase Panel
PI3Kd (p110d/p85a)	PIK3CD-PIK3R1	O00329, P27986	p110D, P110DELTA, PI3K, PI3K-delta, p110-delta	ADP-Glo		Lipid kinase	Lipid Kinase Panel, Diversify Panel
PI3Kg (p110g)	PIK3CG	P48736	p120-PI3K, PI3CG, PI3K, PI3Kgamma, p110-gamma	ADP-Glo		Lipid kinase	Lipid Kinase Panel, Diversify Panel
PI4K2A	PI4K2A	Q9BTU6	PI4KII, PIK42A, RP11-548K23.6	ADP-Glo	ADP-Glo	Lipid kinase	Lipid Kinase Panel	Lipid Kinase Panel
PI4K2B	PI4K2B	Q8TCG2	PI4KIIB, PI4KII-BETA, PIK42B		ADP-Glo	Lipid kinase		Lipid Kinase Panel
PI4Ka	PI4KA	P42356	PIK4CA	ADP-Glo		Lipid kinase	Lipid Kinase Panel
PI4Kb	PI4KB	Q9UBF8	PIK4CB, NPIK	ADP-Glo	ADP-Glo	Lipid kinase	Lipid Kinase Panel	Lipid Kinase Panel
PIK3C2B	PIK3C2B	O00750	C2-PI3K, PI3K-C2beta		ADP-Glo	Lipid kinase		Lipid Kinase Panel
PIK3C2G	PIK3C2G	O75747	PI3K-C2-gamma		ADP-Glo	Lipid kinase		Lipid Kinase Panel
PIK3CA/PIK3R1	PIK3CA-PIK3R1	P42336	MGC142161, MGC142163, p110-alpha, PI3K, PI3K-alpha		ADP-Glo	Lipid kinase		Lipid Kinase Panel, Diversify Panel
PIK3CB D1067A/PIK3R1	PIK3CB (D1067A)-PIK3R1	P42338	PI3K, PI3KBETA, PIK3C1, p110-beta		ADP-Glo	Lipid kinase
PIK3CB D1067V/PIK3R1	PIK3CB (D1067V)-PIK3R1	P42338	PI3K, PI3KBETA, PIK3C1, p110-beta		ADP-Glo	Lipid kinase
PIK3CB D1067Y/PIK3R1	PIK3CB (D1067Y)-PIK3R1	P42338	PI3K, PI3KBETA, PIK3C1, p110-beta		ADP-Glo	Lipid kinase
PIK3CB E1051K/PIK3R1	PIK3CB (E1051K)-PIK3R1	P42338	PI3K, PI3KBETA, PIK3C1, p110-beta		ADP-Glo	Lipid kinase
PIK3CB E633K/PIK3R1	PIK3CB (E633K)-PIK3R1	P42338	PI3K, PI3KBETA, PIK3C1, p110-beta		ADP-Glo	Lipid kinase
PIK3CB L1049R/PIK3R1	PIK3CG (L1049R)-PIK3R1	P42338	PI3K, PI3KBETA, PIK3C1, p110-beta		ADP-Glo	Lipid kinase
PIK3CB/PIK3R1	PIK3CB-PIK3R1	P42338	PI3K, PI3KBETA, PIK3C1, p110-beta		ADP-Glo	Lipid kinase		Lipid Kinase Panel, Diversify Panel
PIK3CD/PIK3R1	PIK3CD-PIK3R1	O00329	p110D, P110DELTA, PI3K, PI3K-delta, p110-delta		ADP-Glo	Lipid kinase		Lipid Kinase Panel, Diversify Panel
PIK3CG	PIK3CG	P48736	p120-PI3K, PI3CG, PI3K, PI3Kgamma, p110-gamma		ADP-Glo	Lipid kinase		Lipid Kinase Panel, Diversify Panel
PIKFYVE	PIKFYVE	Q9Y2I7	CFD, FAB1, FLJ37746, KIAA0981, MGC40423, p235, PIKfyve, PIP5K, PIP5K3, PIPkin-III, Type III PIP kinase	ADP-Glo	ADP-Glo	Lipid kinase	Lipid Kinase Panel	Lipid Kinase Panel
PIM1	PIM1	P11309	PIM	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PIM2	PIM2	Q9P1W9	PIM2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PIM3	PIM3	Q86V86	PIM3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
PIP4K2A	PIP4K2A	P48426	PI42A, PI5P4KA, PIP5K2, PIP5K2A, PIP5KIII	ADP-Glo	ADP-Glo	Lipid kinase	Lipid Kinase Panel	Lipid Kinase Panel
PIP4K2B	PIP4K2B	P78356	PI42B, PIP5K2B	ADP-Glo	ADP-Glo	Lipid kinase	Lipid Kinase Panel	Lipid Kinase Panel
PIP4K2C	PIP4K2C	Q8TBX8	PI42C, PIP5K2C	ADP-Glo	ADP-Glo	Lipid kinase	Lipid Kinase Panel	Lipid Kinase Panel
PIP5K1A	PIP5K1A	Q99755	PIP5K1-alpha, PIP5KIalpha, PtdIns(4)P-5-kinase 1 alpha	ADP-Glo	ADP-Glo	Lipid kinase	Lipid Kinase Panel	Lipid Kinase Panel
PIP5K1B	PIP5K1B	O14986	STM7, PIP5K1-beta	ADP-Glo	ADP-Glo	Lipid kinase	Lipid Kinase Panel	Lipid Kinase Panel
PIP5K1C	PIP5K1C	O60331	PIP5K1-gamma, PIPKIg_v4	ADP-Glo	ADP-Glo	Lipid kinase	Lipid Kinase Panel	Lipid Kinase Panel
PKA	PRKACA	P17612	PKACa	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
PKA (L206R)	PRKACA (L206R)	P17612	PKACa	HotSpot^™		Protein kinase	Mutant Panel
PKAcb	PRKACB	P22694	PKAcb, MGC41879, MGC9320, PKA c-beta	HotSpot^™		Protein kinase	Wild Type Panel
PKAcg	PRKACG	P22612	PKAcg	HotSpot^™		Protein kinase	Wild Type Panel
PKA-DNAJB1	PRKACA-DNAJB1	P25685, P17612	PKACa, Hsp40, Sis1, RSPH16B	HotSpot^™		Protein kinase	Mutant Panel
PKCa	PRKCA	P17252	PRKACA, PKc-alpha, PKCa, PKCalpha	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
PKCb1	PRKCB (1)	P05771	PRKCB1, PKCB, PRKCB2, MGC41878, PKC-beta, PKC-beta1, PKCb1, PKCbeta1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PKCb2	PRKCB (2)	P05771-2	PRKCB1, PKCB, PRKCB2, MGC41878, PKC-beta, PKC-beta2, PKCb2, PKCbeta2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PKCd	PRKCD	Q05655	MAY1, MGC49908, nPKC-delta, PKC-delta, PKCd, PKCdelta	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PKCepsilon	PRKCE	Q02156	PKCE, nPKC-epsilon, PKC-epsilon	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PKCeta	PRKCH	P24723	PKC-L, PKCL, PRKCL, nPKC-eta	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PKCg	PRKCG	P05129	PKCC, PKCG, SCA14, MGC57564, PKC-gamma, PKCgamma	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PKCiota	PRKCI	P41743	PKCI, DXS1179E, MGC26534, nPKC-iota	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PKCmu/PRKD1	PRKD1	Q15139	PKD1, PKD, PKCM, PKc-MU	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PKCnu/PRKD3	PRKD3	O94806	PKD3, EPK2, PKc-NU, PKD3, PRKCN	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PKCtheta	PRKCQ	Q04759	PRKCT, nPKC-theta	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
PKCzeta	PRKCZ	Q05513	PKC2, PKCzeta	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PKD2 (G870E)	PRKD2 (G870E)	Q9BZL6	PKD2, HSPC187	HotSpot^™		Protein kinase	Mutant Panel
PKD2/PRKD2	PRKD2	Q9BZL6	PKD2, HSPC187	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
PKD2/PRKD2 (G848E)	PKD2/PRKD2 (G848E)	Q9BZL6	nPKC-D2, KPCD2, PRKD2	HotSpot^™		Protein kinase	Mutant Panel
PKG1a	PRKG1 (a)	Q13976	PKG1, PGK, PRKG1B, PRKGR1B	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
PKG1b	PRKG1 (b)	P14619	PKG1, PGK, PRKG1B, PRKGR1B	HotSpot^™		Protein kinase	Wild Type Panel
PKG2/PRKG2	PRKG2	Q13237	PKG2, cGKII, PRKGR2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
PKMYT1	PKMYT1	Q99640	MYT1	HotSpotb, ADP-Glo, Probe-displacement		Protein kinase
PKMzeta	PRKCZ (aa184-592)	Q05513	nPKC-zeta, PKC2, PKMzeta	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Wild Type Panel
PKN1/PRK1	PKN1	Q16512	DBK, PKN, PAK1, PRK1, PRKCL1, MGC46204, PKN1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PKN1-ANXA4 (Aex2Pex13)	PKN1-ANXA4 (Aex2Pex13)	Q16512, P09525	PKN, PRK1, PRKCL1, Annexin A4	HotSpot^™		Protein kinase	Mutant Panel
PKN1-TECR (Tex1Pex10)	PKN1-TECR	Q9NZ01, Q16512	DBK, PKN, PAK1, PRK1, PRKCL1, MGC46204, TECR-PKN1, PKN1	HotSpot^™		Protein kinase	Mutant Panel
PKN2/PRK2	PKN2	Q16513	PRK2, PRKCL2, PAK-2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
PKN3/PRK3	PKN3	Q6P5Z2	PRK3, PKNbeta, RP11-545E17.1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
PLK1	PLK1	P53350	STPK13	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
PLK2	PLK2	Q9NYY3	SNK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PLK3	PLK3	Q9H4B4	CNK, FNK, PRK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PLK4/SAK	PLK4	O00444	SAK, STK18	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
PRKX	PRKX	P51817	PKX1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
PYK2	PTK2B	Q14289	CADTK, CAKB, FADK2, FAK2, PKB, PTK, RAFTK, CAK beta	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
RAF1	RAF1 (Y340D/Y341D)	P04049	c-RAF	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
RAF1 (R391W)	RAF1 (R391W)	P04049	c-RAF	HotSpot^™		Protein kinase	Mutant Panel
rDGKA	DGKA Rat	P51556	DAG kinase alpha, 80 kDa diacylglycerol kinase, DAGK1	ADP-Glo		Lipid kinase
rDGKZ	DGKZ Rat	O08560	DAG kinase zeta, 104 kDa diacylglycerol kinase, DGK-IV, Dagk6	ADP-Glo		Lipid kinase
RET	RET	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
RET (A883F)	RET (A883F)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™		Protein kinase	Mutant Panel
RET (E732K)	RET (E732K)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™		Protein kinase	Mutant Panel
RET (E762Q)	RET (E762Q)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET (G691S)	RET (G691S)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET (G810C)	RET (G810C)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET (G810R)	RET (G810R)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET (G810S)	RET (G810S)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET (G810S/M918T)	RET (G810S/M918T)	P07949	Proto-oncogene tyrosine-protein kinase receptor ret, C-ret	HotSpot^™		Protein kinase	Mutant Panel
RET (L730I)	RET (L730I)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET (L730M)	RET (L730M)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET (L790F)	RET (L790F)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™		Protein kinase	Mutant Panel
RET (M918T)	RET (M918T)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET (R749T)	RET (R749T)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET (R813Q)	RET (R813Q)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET (R912P)	RET (R912P)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™		Protein kinase	Mutant Panel
RET (S891A)	RET (S891A)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET (S904A)	RET (S904A)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™		Protein kinase	Mutant Panel
RET (S904F)	RET (S904F)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™		Protein kinase	Mutant Panel
RET (V738A)	RET (V738A)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™		Protein kinase	Mutant Panel
RET (V778I)	RET (V778I)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™		Protein kinase	Mutant Panel
RET (V804E)	RET (V804E)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET (V804L)	RET (V804L)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET (V804L)-KIF5B	RET (V804L)-KIF5B	P33176, P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, KIF5B-RET (V804L)	HotSpot^™		Protein kinase	Mutant Panel
RET (V804M)	RET (V804M)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET (V804M)-KIF5B	RET (V804M)-KIF5B	P33176, P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, KIF5B-RET (V804M)	HotSpot^™		Protein kinase	Mutant Panel
RET (V804M/G810S)	RET (V804M/G810S)	P07949	Proto-oncogene tyrosine-protein kinase receptor ret, C-ret	HotSpot^™		Protein kinase	Mutant Panel
RET (Y791F)	RET (Y791F)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET (Y806C)	RET (Y806C)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™		Protein kinase	Mutant Panel
RET (Y806H)	RET (Y806H)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET (Y806N)	RET (Y806N)	P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51	HotSpot^™		Protein kinase	Mutant Panel
RET-BCR	RET-BCR	P11274, P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, BCR-RET	HotSpot^™		Protein kinase	Mutant Panel
RET-CCDC6 (PTC1)	RET-CCDC6	Q16204, P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, CCDC6-RET	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
RET-KIF5B (Kex15Rex14)	RET-KIF5B	P33176, P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, KIF5B-RET	HotSpot^™		Protein kinase	Mutant Panel
RET-NCOA4 (PTC3)	RET-NCOA4	Q13772, P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, NCOA4-RET	HotSpot^™		Protein kinase	Mutant Panel
RET-PRKAR1A (PTC2)	RET-PRKARA1A	P10644, P07949	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, PRKARA1A-RET	HotSpot^™		Protein kinase	Mutant Panel
RIPK1	RIPK1	Q13546	RIP1, RIP	ADP-Glo		Protein kinase
RIPK2	RIPK2	O43353	CARD3, CARDIAK, CCK, GIG30, RICK, RIP-2, RIP2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
RIPK3	RIPK3	Q9Y572	RIP3, receptor interacting protein 3	HotSpot^™		Protein kinase
RIPK4	RIPK4	P57078	Receptor interacting protein kinase 4, ANKK2, ANKRD3, DIK, MGC129992, MGC129993, PKK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
RIPK5	DSTYK	Q6XUX3	SgK496, SHIK	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
ROCK1	ROCK1	Q13464	P160ROCK	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
ROCK2	ROCK2	O75116	KIAA0619, ROC2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
RON/MST1R	MST1R	Q04912	CD136, CDw136, PTK8, RON	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
ROS/ROS1	ROS1	P08922	ROS, MCF3	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
ROS1 (F2004C)	ROS1 (F2004C)	P08922	ROS, MCF3	HotSpot^™		Protein kinase	Mutant Panel
ROS1 (F2004I)	ROS1 (F2004I)	P08922	ROS, MCF3	HotSpot^™		Protein kinase	Mutant Panel
ROS1 (G2032R)	ROS1 (G2032R)	P08922	ROS, MCF3	HotSpot^™		Protein kinase	Mutant Panel
ROS1 (G2101A)	ROS1 (G2101A)	P08922	ROS, MCF3	HotSpot^™		Protein kinase	Mutant Panel
ROS1 (G2101C)	ROS1 (G2101C)	P08922	ROS, MCF3	HotSpot^™		Protein kinase	Mutant Panel
ROS1 (L2086F)	ROS1 (L2086F)	P08922	ROS, MCF3	HotSpot^™		Protein kinase	Mutant Panel
ROS1-GOPC	ROS1-GOPC	Q9HD26, P08922	ROS, MCF3	HotSpot^™		Protein kinase	Mutant Panel
ROS1-TPM3	ROS1-TPM3	P06753, P08922	ROS, MCF3	HotSpot^™		Protein kinase	Mutant Panel
RSK1	RPS6KA1	Q15418	RSK1, HU-1, MAPKAPK1, p90Rsk	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
RSK2	RPS6KA3	P51812	RSK2, HU-3, MRX19, CLS	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
RSK2 (I416V)	RPS6KA3 (I416V)	P51812	RSK2, HU-3, MRX19, CLS	HotSpot^™		Protein kinase	Mutant Panel
RSK2 (L608F)	RPS6KA3 (L608F)	P51812	RSK2, HU-3, MRX19, CLS	HotSpot^™		Protein kinase	Mutant Panel
RSK3	RPS6KA2	Q15349	RSK3, HU-2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
RSK4	RPS6KA6	Q9UK32	RSK4	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
SBK1	SBK1	Q52WX2	SH3-binding kinase 1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
SGK1	SGK1	O00141	SGK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
SGK2	SGK2	Q9HBY8	H-SGK2, dJ138B7.2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
SGK3/SGKL	SGK3	Q96BR1	CISK, SGK2, SGKL	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
SIK1	SIK1	P57059	SIK, MSK, SNF1LK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
SIK2	SIK2	Q9H0K1	QIK, SNF1LK2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
SIK3	SIK3	Q9Y2K2	L19, QSK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
SLK/STK2	SLK	Q9H2G2	KIAA0204, STK2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel, Diversify Panel
SNARK/NUAK2	NUAK2	Q9H093	SNARK, DKFZp434J037	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
SNRK	SNRK	Q9NRH2	SNF1-related kinase	HotSpot^™		Protein kinase	Wild Type Panel
SPHK1	SPHK1	Q9NYA1	Sphingosine kinase 1	ADP-Glo		Lipid kinase	Lipid Kinase Panel
SPHK2	SPHK2	Q9NRA0	Sphingosine kinase 2	ADP-Glo		Lipid kinase	Lipid Kinase Panel
SRMS	SRMS	Q9H3Y6	C20orf148, SRM, dJ697K14.1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
SRPK1	SRPK1	Q96SB4	SFRSK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
SRPK2	SRPK2	P78362	SFRSK2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
SSTK/TSSK6	TSSK6	Q9BXA6	FLJ24002, SSTK	HotSpot^™		Protein kinase	Wild Type Panel
STK16	STK16	O75716	TSF1, PKL12, MPSK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
STK17B	STK17B	O94768	DRAK2		³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
STK21/CIT	CIT	O14578	CRIK, STK21/CIT	HotSpot^™		Protein kinase	Wild Type Panel
STK22D/TSSK1	TSSK1B	Q9BXA7	TSSK1, FKSG81, SPOGA4, STK22D	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
STK25/YSK1	STK25	O00506	YSK1, SOK1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
STK32A/YANK1	STK32A	Q8WU08	Serine/threonine-protein kinase 32A, Yet another novel kinase 1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
STK32b/YANK2	STK32B	Q9NY57	YANK2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
STK32c/YANK3	STK32C	Q86UX6	YANK3	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
STK33	STK33	Q9BYT3	STK33	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
STK35/CLIK1	STK35	Q8TDR2	Serine/threonine-protein kinase 35, CLP-36-interacting kinase 1, PDLIM1-interacting kinase 1, PDIK1, STK35L1	HotSpot^™		Protein kinase	Wild Type Panel
STK38/NDR1	STK38	Q15208	NDR1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
STK38L/NDR2	STK38L	Q9Y2H1	NDR2, KIAA0965	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
STK39/STLK3	STK39	Q9UEW8	STLK3, DCHT, SPAK	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
SYK	SYK	P43405	SYK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
SYK aa356-635	SYK (aa356-635)	P43405	SYK		³³PanQinase^™, ADP-Glo	Protein kinase
TAK1	MAP3K7	O43318	MAP3K7, TGF1a, MEKK7, TAK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
TAOK1	TAOK1	Q7L7X3	TAO1, KIAA1361, MAP3K16, MARKK,	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
TAOK2/TAO1	TAOK2	Q9UL54	KIAA0881, MAP3K17, PSK, PSK1, TAO1, TAO2	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
TAOK3/JIK	TAOK3	Q9H2K8	DPK, JIK, MAP3K18, TAO kinase 3	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
TBK1	TBK1	Q9UHD2	CDC37, HSPCA, HSPCB, IKBKG, NAK, T2K, TANK, TRAF2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
TEC	TEC	P42680	PSCTK4	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
TESK1	TESK1	Q15569	TESK1	HotSpot^™		Protein kinase	Wild Type Panel
TESK2	TESK2	Q96S53	TESK2	HotSpot^™		Protein kinase	Wild Type Panel
TGFBR2	TGFBR2	P37173	HNPCC6, MFS2, RIIC, TGFbeta-RII, TBR-II, TRBII	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
TIE2 (A1124V)	TEK (A1124V)	Q02763	VMCM, TIE-2, VMCM1, CD202B	HotSpot^™		Protein kinase	Mutant Panel
TIE2 (P883A)	TEK (P883A)	Q02763	VMCM, TIE-2, VMCM1, CD202B	HotSpot^™		Protein kinase	Mutant Panel
TIE2 (R849W)	TEK (R849W)	Q02763	VMCM, TIE-2, VMCM1, CD202B	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
TIE2 (R915C)	TIE2 (R915C)	Q02763	TIE-2, hTIE2, TEK, p140 TEK	HotSpot^™		Protein kinase	Mutant Panel
TIE2 (Y1108F)	TEK (Y1108F)	Q02763	VMCM, TIE-2, VMCM1, CD202B	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
TIE2 (Y897C)	TEK (Y897C)	Q02763	VMCM, TIE-2, VMCM1, CD202B	HotSpot^™		Protein kinase	Mutant Panel
TIE2 (Y897H)	TIE2 (Y897H)	Q02763	TIE-2, hTIE2, TEK, p140 TEK	HotSpot^™		Protein kinase	Mutant Panel
TIE2 (Y897H/R915C)	TIE2 (Y897H/R915C)	Q02763	TIE-2, hTIE2, TEK, p140 TEK	HotSpot^™		Protein kinase	Mutant Panel
TIE2 (Y897S)	TEK (Y897S)	Q02763	VMCM, TIE-2, VMCM1, CD202B	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
TIE2/TEK	TEK	Q02763	VMCM, TIE-2, VMCM1, CD202B	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
TLK1	TLK1	Q9UKI8	PKU-beta, KIAA0137	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
TLK2	TLK2	Q86UE8	MGC44450, PKU-ALPHA	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
TNIK	TNIK	Q9UKE5	TRAF2 and NCK interacting kinase, KIAA0551, MAP4K7	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
TNK1	TNK1	Q13470	TNK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
TRKA	NTRK1	P04629	MTC, TRK, TRK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel, Tyrosine Panel	Wild Type Panel, Diversify Panel
TRKA (A608D)	NTRK1 (A608D)	P04629	MTC, TRK, TRK1	HotSpot^™		Protein kinase	Mutant Panel
TRKA (F589L)	NTRK1 (F589L)	P04629	MTC, TRK, TRK1	HotSpot^™		Protein kinase	Mutant Panel
TRKA (G595R)	NTRK1 (G595R)	P04629	MTC, TRK, TRK1	HotSpot^™		Protein kinase	Mutant Panel
TRKA (G595R/A608D)	NTRK1 (G595R/A608D)	P04629	MTC, TRK, TRK1	HotSpot^™		Protein kinase	Mutant Panel
TRKA (G595R/G667A)	NTRK1 (G595R/G667A)	P04629	MTC, TRK, TRK1	HotSpot^™		Protein kinase	Mutant Panel
TRKA (G595R/G667C)	NTRK1 (G595R/G667C)	P04629	MTC, TRK, TRK1	HotSpot^™		Protein kinase	Mutant Panel
TRKA (G595R/G667S)	NTRK1 (G595R/G667S)	P04629	MTC, TRK, TRK1	HotSpot^™		Protein kinase	Mutant Panel
TRKA (G595R/L657M)	NTRK1 (G595R/L657M)	P04629	MTC, TRK, TRK1	HotSpot^™		Protein kinase	Mutant Panel
TRKA (G667A)	NTRK1 (G667A)	P04629	MTC, TRK, TRK1	HotSpot^™		Protein kinase	Mutant Panel
TRKA (G667C)	NTRK1 (G667C)	P04629	MTC, TRK, TRK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Mutant Panel	Mutant Panel
TRKA (G667S)	NTRK1 (G667S)	P04629	MTC, TRK, TRK1	HotSpot^™		Protein kinase	Mutant Panel
TRKA (L657M)	NTRK1 (L657M)	P04629	MTC, TRK, TRK1	HotSpot^™		Protein kinase	Mutant Panel
TRKA-TFG	NTRK1-TFG	Q92734, P04629	TRKA, TGF-NTRK1	HotSpot^™		Protein kinase	Mutant Panel
TRKA-TPM3	NTRK1-TPM3	P06753, P04629	TRKA, TPM3-NTRK1	HotSpot^™		Protein kinase	Mutant Panel
TRKA-TPR	NTRK1-TPR	P12270, P04629	TRKA, TPR-NTRK1	HotSpot^™		Protein kinase	Mutant Panel
TRKB	NTRK2	Q16620	GP145-TrkB	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
TRKC	NTRK3	Q16288	GP145-TrkC	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
TRKC (G623E)	NTRK3 (G623E)	Q16288	GP145-TrkC	HotSpot^™		Protein kinase	Mutant Panel
TRKC (G623R)	NTRK3 (G623R)	Q16288	GP145-TrkC	HotSpot^™		Protein kinase	Mutant Panel
TRKC (G623R/L686M)	NTRK3 (G623R/L686M)	Q16288	GP145-TrkC	HotSpot^™		Protein kinase	Mutant Panel
TRKC (G696A)	NTRK3 (G696A)	Q16288	GP145-TrkC	HotSpot^™		Protein kinase	Mutant Panel
TRKC (L686M)	NTRK3 (L686M)	Q16288	GP145-TrkC	HotSpot^™		Protein kinase	Mutant Panel
TRPM7/CHAK1	TRPM7	Q96QT4	CHAK1	HotSpot^™		Protein kinase	Atypical Panel
TSSK2	TSSK2	Q96PF2	DGS-G, SPOGA2, FLJ38613, TSK2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
TSSK3/STK22C	TSSK3	Q96PN8	STK22C, STK22D, SPOGA3	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
TSSK4	TSSK4	Q6SA08	Testis-specific serine/threonine-protein kinase 4, Serine/threonine-protein kinase 22E, C14orf20, STK22E, TSSK5	HotSpot^™		Protein kinase	Wild Type Panel
TTBK1	TTBK1	Q5TCY1	KIAA1855, BDTK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
TTBK1 aa1-480	TTBK1 (aa1-480)	Q5TCY1	KIAA1855, BDTK		³³PanQinase^™, ADP-Glo	Protein kinase
TTBK2	TTBK2	Q6IQ55	KIAA0847	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
TTK	TTK	P33981	ESK, MPS1L1, MPS1, PYT	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
TXK	TXK	P42681	BTKL, PSCTK5, PTK4, RLK	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
TYK1/LTK	LTK	P29376	TYK1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
TYK2	TYK2	P29597	JTK1	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
TYK2 JH1 & JH2	TYK2 (JH1&2)	P29597	Non-receptor tyrosine-protein kinase TYK2	HotSpot^™	³³PanQinase^™	Protein kinase
TYK2 JH2	TYK2 JH2	P29597	JTK1	Probe-displacement		Protein kinase
TYRO3/SKY	TYRO3	Q06418	BYK, Brt, Dtk, Sky, Tif	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
ULK1	ULK1	O75385	UNC51, Unc51.1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Diversify Panel	Wild Type Panel, Diversify Panel
ULK2	ULK2	Q8IYT8	ATG1B, KIAA0623, Unc51.2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
ULK3	ULK3	Q6PHR2	FLJ90566, DKFZP434C131	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
VRK1	VRK1	Q99986	VRK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
VRK2	VRK2	Q86Y07	VRK2	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
WEE1	WEE1	P30291	WEE1hu	HotSpot^™, ADP-Glo, Probe-displacement	³³PanQinase^™, ADP-Glo	Protein kinase		Wild Type Panel
WEE2	WEE2	P0C1S8	WEE1B	HotSpot^™		Protein kinase
WNK1	WNK1	Q9H4A3	KDP, KIAA0344, PHA2C, PRKWNK1	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel	Wild Type Panel
WNK2	WNK2	Q9Y3S1	KIAA1760, NY-CO-43, P/OKcl.13, PRKWNK2, SDCCAG43	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
WNK3	WNK3	Q9BYP7	KIAA1566, PRKWNK3	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
YES/YES1	YES1	P07947	C-YES, HsT441, P61-YES, YES1, YES	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
YES1 (T348I)	YES1 (T348I)	P07947	C-YES, HsT441, P61-YES, YES1, YES	HotSpot^™		Protein kinase	Mutant Panel
YSK4/MAP3K19	MAP3K19	Q56UN5	M3K19, RCK, YSK4	HotSpot^™		Protein kinase	Wild Type Panel
ZAK/MLTK	MAP3K20	Q9NYL2	MLTK, mlklak, ZAK	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel
ZAP70	ZAP70	P43403	SRK, STD, TZK	HotSpot^™	³³PanQinase^™, ADP-Glo	Protein kinase	Wild Type Panel, Tyrosine Panel	Wild Type Panel
ZAP70 (Y319F)	ZAP70 (Y319F)	P43403	SRK, STD, TZK	HotSpot^™		Protein kinase	Mutant Panel
ZIPK/DAPK3	DAPK3	O43293	ZIPK/DAPK3, ZIP, ZIPK	HotSpot^™	³³PanQinase^™	Protein kinase	Wild Type Panel	Wild Type Panel

Selectivity panels, US facility (HotSpot)

Panel	Kinases	ATP	Doses	View Panel
Wild Type Kinase Panel	381	1 µM, 10 µM, Km, 1 mM	1 & 10	View Panel
Mutant Kinase Panel	354	1 µM, 10 µM, Km	1 & 10	View Panel
Tyrosine Kinase Panel	79	1 µM, 10 µM, Km, 1 mM	1 & 10	View Panel
Diversify Panel	70	Km & 1 mM	1 & 10	View Panel
Lipid Kinase Panel	26	1 µM, 10 µM, 1mM	1 & 10	View Panel
Atypical Kinase Panel	24	1 µM, 10 µM, Km	1 & 10	View Panel
Diacylglycerol Kinase Panel	10	50 µM, 200 µM, Km, 1 mM	1 & 10	View Panel

View screening schedule for 1uM, 10uM, 100uM*, Km ATP

Applicable to Wildtype, Mutant, Atypical, Lipid, and DGK Panels

Month 2026	Monthly Run #	Anticipated Start Date	Assay Condition Forms must be received by
December 2025*	1	Dec 2, 2025	Nov 26, 2025
January*	1	Jan 5, 2026	Dec 31, 2025
January	2	Jan 20, 2026	Jan 14, 2026
February*	1	Feb 2, 2026	Jan 28, 2026
February	2	Feb 16, 2026	Feb 11, 2026
March*	1	Mar 2, 2026	Feb 25, 2026
March	2	Mar 16, 2026	Mar 11, 2026
April*	1	Apr 6, 2026	Apr 1, 2026
April	2	Apr 20, 2026	Apr 15, 2026
May*	1	May 4, 2026	Apr 29, 2026
May	2	May 18, 2026	May 13, 2026
June*	1	Jun 1, 2026	May 27, 2026
June	2	Jun 15, 2026	Jun 10, 2026
July*	1	Jul 6, 2026	Jul 1, 2026
July	2	Jul 20, 2026	Jul 15, 2026
August*	1	Aug 3, 2026	Jul 29, 2026
August	2	Aug 17, 2026	Aug 12, 2026
September*	1	Sep 1, 2026	Aug 26, 2026
September	2	Sep 14, 2026	Sep 9, 2026
October*	1	Oct 5, 2026	Sep 30, 2026
October	2	Oct 19, 2026	Oct 14, 2026
November*	1	Nov 2, 2026	Oct 28, 2026
November	2	Nov 16, 2026	Nov 11, 2026
December*	1	Dec 7, 2026	Dec 2, 2026

*100uM ATP may be requested only for dates listed with * (first run of the month)

Note: In order to facilitate planning, please provide an electronic copy of the assay condition form as early as possible. Assay forms must be returned by 4 pm EST on the date of the deadline to be considered.

View screening schedule for 1mM ATP

Applicable to Wildtype, Mutant, Atypical, Lipid, and DGK Panels

Month 2026	Anticipated Start Date	Assay Condition Forms must be received by	Compounds must be received by
November 2025	Nov 24, 2025	Nov 19, 2025	Nov 19, 2025
December 2025	Dec 15, 2025	Dec 10, 2025	Dec 10, 2025
January	Jan 26, 2026	Jan 21, 2026	Jan 21, 2026
February	Feb 23, 2026	Feb 18, 2026	Feb 18, 2026
March	Mar 23, 2026	Mar 18, 2026	Mar 18, 2026
April	Apr 27, 2026	Apr 22, 2026	Apr 22, 2026
May	May 26, 2026	May 20, 2026	May 20, 2026
June	Jun 22, 2026	Jun 17, 2026	Jun 17, 2026
July	Jul 27, 2026	Jul 22, 2026	Jul 22, 2026
August	Aug 24, 2026	Aug 19, 2026	Aug 19, 2026
September	Sep 21, 2026	Sep 16, 2026	Sep 16, 2026
October	Oct 26, 2026	Oct 21, 2026	Oct 21, 2026
November	Nov 23, 2026	Nov 18, 2026	Nov 18, 2026
December	Dec 21, 2026	Dec 16, 2026	Dec 16, 2026

** Any kinases that are incompatible with 1mM ATP can be run at either Km or 100uM ATP
Note: In order to facilitate planning, please provide an electronic copy of the assay condition form as early as possible. Assay forms must be returned by 4 pm EST on the date of the deadline to be considered.

View screening schedule for Diversify Panel 1mM ATP

Applicable to Diversify Panel (1mM ATP)

Month 2026	Anticipated Start Date	Assay Condition Forms must be received by	Compounds must be received by
December 2025	Dec 8, 2025	Dec 3, 2025	Dec 3, 2025
January	Jan 12, 2026	Jan 7, 2026	Jan 7, 2026
February	Feb 9, 2026	Feb 4, 2026	Feb 4, 2026
March	Mar 9, 2026	Mar 4, 2026	Mar 4, 2026
April	Apr 13, 2026	Apr 8, 2026	Apr 8, 2026
May	May 11, 2026	May 6, 2026	May 6, 2026
June	Jun 8, 2026	Jun 3, 2026	Jun 3, 2026
July	Jul 13, 2026	Jul 8, 2026	Jul 8, 2026
August	Aug 10, 2026	Aug 5, 2026	Aug 5, 2026
September	Sep 8, 2026	Sep 2, 2026	Sep 2, 2026
October	Oct 12, 2026	Oct 7, 2026	Oct 7, 2026
November	Nov 9, 2026	Nov 4, 2026	Nov 4, 2026
December	Dec 14, 2026	Dec 9, 2026	Dec 9, 2026

Selectivity panels, German facility (33PanQinase)

Panels	Kinases	ATP	Doses	View Panel
Wild Type Kinase Panel	381	Km	1, 2 & 6	View Panel
Mutant Kinase Panel	96	Km	1, 2 & 6	View Panel
Diversify Panel	70	Km	1, 2 & 6	View Panel
Lipid Kinase Panel	19	Km	1, 2 & 6	View Panel

View screening schedule for German Facility Panels

Applicable to Wild Type, Mutant, Diversify, and Lipid Kinase Panels

Month 2026	Start of testing	Latest arrival of sample(s)
December 2025	Nov 27, 2025	Nov 30, 2025
January	Jan 12, 2026	Jan 8, 2026
February	Feb 9, 2026	Feb 5, 2026
March	Mar 9, 2026	Mar 5, 2026
April	Apr 7, 2026	Apr 1, 2026
May	May 4, 2026	Apr 29, 2026
June	Jun 1, 2026	May 28, 2026
July	Jun 29, 2026	Jun 25, 2026
August	Aug 3, 2026	Jul 30, 2026
September	Aug 31, 2026	Aug 27, 2026
October	Sep 28, 2026	Sep 24, 2026
November	Nov 2, 2026	Oct 29, 2026
December	Nov 30, 2026	Nov 26, 2026

Specialty Profilers (US)

Panel	Size	Data
EGFR Mutant Profiler	65	Data sheet
RET Mutant Profiler	36	Data sheet
CDK Profiler	35	Data sheet
c-MET Mutant Profiler	32	Data sheet
ALK Mutant Profiler	29	Data sheet
c-KIT Mutant Profiler	24	Data sheet
FGFR2 Mutant Profiler	19	Data sheet
BRAF Mutant Profiler	16	Data sheet
ABL1 Mutant Profiler	15	Data sheet
TRKA Mutant Profiler	15	Data sheet
FLT3 Mutant Profiler	13	Data sheet
TIE Mutant Profiler	11	Data sheet
ERBB2 Mutant Profiler	10	Data sheet
FGFR3 Mutant Profiler	6	Data sheet
TRKC Mutant Profiler	6	Data sheet
FGFR4 Mutant Profiler	5	Data sheet

Specialty Profilers (Germany)

Panel	Size	Data
CDK Profiler	43	Data sheet
Lipid Kinase Profiler	19	Data sheet
EGFR Mutant Profiler	11	Data sheet
KIT Mutant Profiler	10	Data sheet
MET Mutant Profiler	10	Data sheet
RET Mutant Profiler	10	Data sheet
ABL1 Mutant Profiler	9	Data sheet
ALK Mutant Profiler	8	Data sheet