List of available EGFR Assays
Target | Biochemical and Biophysical Assays | Cell and In Vivo Assays | Tumor Cell Lines |
---|---|---|---|
EGFR | ³³PanQinase, HotSpot, SPR | Cell Proliferation Assay, Kinase-dependent Transformation Assay | A431 |
EGFR (A1048V) | - | Cell Proliferation Assay | MKN45 |
EGFR (A289V/G614S) | - | Cell Proliferation Assay | RL95-2 |
EGFR (A755D) | - | Cell Proliferation Assay | LOU-NH91 |
EGFR (A763_Y764insFHEA) | HotSpot | - | - |
EGFR (A763_Y764insFQEA) | HotSpot | - | - |
EGFR (A767_S768insTLA) | HotSpot | - | - |
EGFR (C775S/T790M/L858R) | HotSpot | - | - |
EGFR (C797A) | HotSpot | - | - |
EGFR (C797S) | ³³PanQinase, HotSpot | - | - |
EGFR (C797S/L858R) | ³³PanQinase, HotSpot | - | - |
EGFR (d746) | HotSpot | - | - |
EGFR (d746-750) | ³³PanQinase, HotSpot | Cell Proliferation Assay, In Vivo Testing | HCC827, PC-9 |
EGFR (d746-750/C775S/T790M/L858R) | ³³PanQinase, HotSpot | - | - |
EGFR (d746-750/C797A) | HotSpot | - | - |
EGFR (d746-750/C797S) | ³³PanQinase, HotSpot | Cellular Phosphorylation Assay | - |
EGFR (d746-750/T790M) | HotSpot | Cellular Phosphorylation Assay | - |
EGFR (d746-750/T790M/C797S) | ³³PanQinase, HotSpot | Cellular Phosphorylation Assay, Kinase-dependent Transformation Assay | - |
EGFR (d746-750/T790M/C797S/L858R) | HotSpot | - | - |
EGFR (d747-749) | HotSpot | - | - |
EGFR (d747-749/A750P) | ³³PanQinase, HotSpot | Cellular Phosphorylation Assay | - |
EGFR (d747-752/A755D) | - | Cell Proliferation Assay | LOU-NH91 |
EGFR (d747-752/P753S) | ³³PanQinase, HotSpot | - | - |
EGFR (d752-759) | ³³PanQinase, HotSpot | Cellular Phosphorylation Assay | - |
EGFR (D761Y) | HotSpot | - | - |
EGFR (D770_N771insNPG) | HotSpot | - | - |
EGFR (D770_N771insNPG/T790M) | HotSpot | - | - |
EGFR (D770GY) | HotSpot | - | - |
EGFR (G719C) | ³³PanQinase, HotSpot | - | - |
EGFR (G719D) | HotSpot | - | - |
EGFR (G719S) | ³³PanQinase, HotSpot | Cellular Phosphorylation Assay | - |
EGFR (G917R) | - | Cell Proliferation Assay | MM1.S |
EGFR (I646L) | - | Cell Proliferation Assay | HeLa |
EGFR (K716A) | HotSpot | - | - |
EGFR (K716A/C797S/L858R) | HotSpot | - | - |
EGFR (K716A/T790M/C797S/L858R) | HotSpot | - | - |
EGFR (K716Q/L718Q) | HotSpot | - | - |
EGFR (K728A) | HotSpot | - | - |
EGFR (K728A/T790M/C797S/L858R) | HotSpot | - | - |
EGFR (L718Q) | ³³PanQinase, HotSpot | - | - |
EGFR (L747S) | HotSpot | - | - |
EGFR (L792F) | HotSpot | - | - |
EGFR (L792F/L858R) | HotSpot | - | - |
EGFR (L792H) | HotSpot | - | - |
EGFR (L792H/C797S/L858R) | HotSpot | - | - |
EGFR (L815F) | - | Cell Proliferation Assay | RS4;11 |
EGFR (L858R) | ³³PanQinase, HotSpot | Cellular Phosphorylation Assay | - |
EGFR (L861Q) | ³³PanQinase, HotSpot | Cellular Phosphorylation Assay | - |
EGFR (N771_P772insH) | HotSpot | - | - |
EGFR (R1068 nonsense) | - | Cell Proliferation Assay | NALM-6 |
EGFR (R309G) | - | Cell Proliferation Assay | Calu-6, HCC38 |
EGFR (R451C) | - | Cell Proliferation Assay | Jurkat |
EGFR (R973Q) | - | Cell Proliferation Assay | Ishikawa |
EGFR (R999A) | HotSpot | - | - |
EGFR (S1025N) | - | Cell Proliferation Assay | HEC-1-A |
EGFR (S511fs) | - | Cell Proliferation Assay | MOLT-4 |
EGFR (T751I) | - | Cell Proliferation Assay | RPMI-8226 |
EGFR (T790M) | ³³PanQinase, HotSpot | Cellular Phosphorylation Assay | - |
EGFR (T790M/C797S) | HotSpot | - | - |
EGFR (T790M/C797S/L858R) | ³³PanQinase, HotSpot | Cellular Phosphorylation Assay | - |
EGFR (T790M/L792F/C797S/L858R) | HotSpot | - | - |
EGFR (T790M/L792F/L858R) | HotSpot | - | - |
EGFR (T790M/L792H/C797S/L858R) | HotSpot | - | - |
EGFR (T790M/L792H/L858R) | HotSpot | - | - |
EGFR (T790M/L858R) | ³³PanQinase, HotSpot | Cellular Phosphorylation Assay | - |
EGFR (V769_D770insGE) | HotSpot | - | - |