Drug Discovery Blog

Every drug discovery program has its own challenges. Scientists at Reaction Biology have 20 years of experience in problem-solving and decision making. Via blogs, we like to share some of our experiences and insight into our assays with the drug discovery community to support your journey to a preclinical drug candidate.

Biophysical characterization of compounds disrupting the SARS-CoV-2 Spike – ACE2 interaction using SPR

Without rock-solid biophysical predictors of binding affinity and kinetics, the road from molecular screening and simulation to cell-based assays and in vivo testing is virtually unnavigable. Fully characterizing your COVID-19 drug candidate with a proven SPR methodology is the fundament of the successful development of efficacious drugs.