FAQs

Reaction Biology offers compound screening against more than 1000 targets and provides high-quality proteins and customized assay development. Our global team of business development representatives will be happy to talk to you directly about any questions and requests. 

See our FAQ list below for a quick answer to the most common questions.

How do I order your services or products?

We are happy to produce a quote based on your requirements. Provide a PO number and other payment information including your as VAT number if applicable, and send it to requests [at] reactionbiology.com.

To purchase our recombinant proteins and substrates you can use our online shop for kinase-related and epigenetic-related products .

How do I provide information about my compounds and assay condition information?

Please see your quotation to find out whether the assay is performed at our US or German research facility and follow the instructions in our assay condition forms available for download below.

Compound submission for US site
  • Kindly complete the assay condition form with detailed compound info and preferred test conditions. Avoid generic compound names such as “Compound A”, “Compound 1”, etc. 
     
  • Return an electronic copy of the form and include a hard copy in the compound shipment. Reaction Biology scientists will perform the tests ONLY based on the assay conditions described in the electronic copy of this form.
Compound submission for German site
  • Kindly complete the assay condition form for biochemical assays or cell-based assays with detailed compound information and preferred test conditions. 
     
  • Return an electronic copy of the form and include a hard copy in the compound shipment. Reaction Biology scientists will perform the tests ONLY based on the assay conditions described in the electronic copy of this form. 

How do I prepare my compounds for screening?

Please see information for standard assays below. For HTS screening, please contact us directly.

Compound preparation for US site

Please choose one of the following two options: 

Option 1: Reaction Biology’s preference is to receive your compounds as DMSO stock

For smaller panels (under 50 targets), we require 20 μl of 10 mM DMSO stock. For larger panels, we require 50 μl to 100 μl of 10 mM DMSO stock. Sample concentration requirements may vary based on test conditions. For DMSO stock, shipment and delivery in dry ice are preferred for compound stability. 

Option 2: We also accept compounds in powder form. Anywhere from 0.5 mg to 3 mg should be enough for most profiling requests, and can be delivered at room temperature or a temperature of your preference. It is Reaction Biology’s policy not to weigh customer compounds onsite. 

The following is required to process your samples: 
a) The exact molecular weight of each compound. 
b) The exact weight of each compound. 
c) The vessel containing the powder should be large enough to re-suspend the powder to 10 mM. 
d) For a larger number of compounds delivered in powder form, a processing fee may be applied. 
e) If you provide powder stock greater than 5 mg, the compound stock will be aliquoted at Reaction Biology for a service fee.

Additional powder stock will be stored for a period of six months, and the below charges will apply: 

Weighing of sample stock (1-10 compounds) US$ 10 per/sample
Weighing of sample stock (11+ compounds) US$ 10 per sample for first 10 compounds, additional samples US$ 5 each
Shipment of remaining powder stock (Domestic) US$ 50 plus shipping charges
Shipment of remaining powder stock (International) US$ 100 plus shipping charges
   
Compound preparation for German site

The assay condition forms for biochemical assays or cell-based assays contain detailed information for compound preparation.

Where do I ship my compounds?

Shipping to US site.

Reaction Biology accepts deliveries during business hours (Monday – Friday, 8:30 am- 5:30 pm). No packages will be processed on weekends and certain United States holidays. 

International Shipments: Packages shipped from outside of the US will require a TSCA form. The TSCA form should be filled out and placed in the exterior pouch. It is best to include at least 2 copies of the TSCA form with your shipment. This will speed the passage of the parcel through US customs. 

The AWB # is the Airway Bill number. It is the number (often called the tracking number) that the shipping company assigns to your package. Placing it on the sheet ensures that it is clear that the TSCA form pertains to your package. Additionally, please fill out the product description section of the TSCA form with a description of the materials you send. A harmonization code for your shipment may be required to pass through customs. 

When filling out your shipment documents, please put in your address in the 'return to' line so that if the package needs to be returned by the courier, it is sent back to you. Reaction Biology accepts packages from any international delivery company, such as FedEx, World Courier, and DHL International etc. We do not recommend TNT because TNT has a higher rate of delaying package delivery.

Shipping address:
Compound Management 
Reaction Biology Corp. 
One Great Valley Parkway, Suite 2 
Malvern, PA 19355 USA 
Phone: 610-722-0247 
Fax: 610-722-0246 
Info [at] reactionbiology.com

Shipping to German site.

Reaction Biology Europe accepts deliveries during business hours (Monday – Friday, 8:30 am- 4:30 pm). No packages will be processed on weekends and German holidays.

International shipments:
Please state the TARIC Code 2942000000 (other organic compounds) in the customs documents and indicate that the content is “Only for laboratory testings, not for use in humans or animals, only smallest amounts and of no commercial value”. 

If possible, do not exceed a commercial value of 10 €.

Shipping address:

Cellular Drug Discovery Biochemical Drug Discovery
Dr. Franziska Fimm-Todt Dr. Frank Totzke
Reaction Biology Europe GmbH Reaction Biology Europe GmbH
Engesserstr. 4 Engesserstr. 4
79108 Freiburg 79108 Freiburg
Germany Germany
Phone:    +49-761-769996 1646 Phone: +49-761-769996 1723
Fax:        +49-761-769996 1781 Fax:     +49-761-769996 1781
Email:  F.Fimm [at] reactionbiology.de     Email: f.totzke [at] reactionbiology.de
CC: cellservice [at] reactionbiology.de          CC: d.mueller [at] reactionbiology.de
   
   

How do I pay for your services/products?

Payment information is provided on the invoice. To arrange prepayment or pay via credit card, please contact requests [at] reactionbiology.com and reference the quotation number. 

Products ordered in the online shops can be either paid by credit card directly or via cheque/wire transfer when a purchase order is provided.

Are your labs certified?

Reaction Biology Europe GmbH is certified according to DIN EN ISO 9001:2015 comprising the areas of production and sale of recombinant protein products as well as establishment and sale of biochemical, cellular, and in vivo testing services for the development of new drugs targeting cancer.

The ISO 9001 certificate is based on a number of quality management principles to ensure that customers get consistent, good quality products and services.
 

Certificate_English

Zertifikat_Deutsch