Heat Shock Protein Assays
Heat shock proteins (HSPs) are abundant proteins that usually interact with newly synthesized proteins to support their folding for stabilization and proper function (chaperone function). In cancer cells, HSPs are often overexpressed and implicated in tumor progression and therapy resistance. High HSP levels prevent apoptosis associated with developing malignancies and prevent apoptosis caused by therapy.
Targeting HSPs as a drug combination strategy can enable apoptosis in treated tumor cells to overcome resistance and successful therapy.
- Compound screening is available for low scale, high scale, and high throughput screening
- Please inquire for customized screening options and assay development for further HSP targets