Xenograft Models

Xenograft mouse models are the most frequently used tumor models for the evaluation of in vivo efficacy of novel anti-cancer drug candidates. Cell line-derived xenograft tumor models (CDX) are well established with a long history of tumor model characterization and reference drug efficacy data.

Xenograft models are based on the implantation of human tumor cells into immunocompromised mice to avoid graft versus host reaction of the mouse against the human tumor tissue. Reaction Biology's in vivo tumor models are derived from a variety of origins such as breast, colon, lung, skin, blood. Our mouse xenografts comprise subcutaneous, orthotopic, and metastasis models.

• Choose one of our available mouse xenografts or contact us for the establishment of the xenograft model for your specific in vivo efficacy study
• All in vivo tumor models are well established and validated
• Custom-tailored reports written by Ph.D. level medical writers will be provided for every in vivo study
• Science-driven study setup with a focus on reproducible and meaningful results
• Meticulous documentation of drug efficacy testing following GV-Solas and ISO 9001 requirements

Reaction Biology's xenograft mouse models are available to clients around the world. Your assigned business development manager will guide you through the process of your animal study and answer all inquiries about our tumor models. Please contact us to discuss your in vivo tumor model needs.