Human Xenograft Models

Human xenograft tumor models are the most frequently used test systems for the evaluation of in vivo efficacy of novel anti-cancer drug candidates. Cell line-derived xenograft tumor models (CDX) are well established with a long history of tumor model characterization and reference drug efficacy data.

Xenograft models are based on the implantation of human tumor cells into immunocompromised mice to avoid graft versus host reaction of the mouse against the human tumor tissue. Reaction Biology's in vivo tumor models are derived from a variety of origins such as breast, colon, lung, skin, blood. In vivo efficacy studies can be performed on subcutaneous, orthotopic, and metastasis models.

• Our CRO offers in vivo efficacy studies with well-validated tumor models
• Custom-tailored reports written by Ph.D. level medical writers will be provided for every in vivo study
• Science-driven study setup with a focus on reproducible and meaningful results