Human Xenograft Tumor Models

Human xenograft tumor models are the most frequently used test systems for the evaluation of in vivo efficacy of novel anti-cancer drug candidates. Cell line-derived xenograft tumor models are well established with a long history of model characterization.

Xenograft tumor models are based on the implantation of human tumor cells into immunocompromised mice. Immunodeficient mice are used to avoid graft versus host reaction against the human tumor tissue. Reaction Biology provides models from a high variety of tumor origins such as breast, colon, lung, skin, blood, and performs testing after subcutaneous or orthotopic implantation as well as evaluation of metastasis.

• Efficient drug testing with well-validated tumor models
• Custom-tailored reports written by Ph.D. level medical writers will be provided for every study
• Science-driven study setup with a focus on reproducible and meaningful results