Reaction Biology
  • English
  • 中文
  • Overview
  • Services
    • Box 1
      • Target-specific Assays
      • Integrated Kinase Discovery Services
        • Kinase Assays Services
        • Kinase Panel Screening
        • Cellular Kinase Assays
          • BaF3 Cell Proliferation Assay
          • Cellular Phosphorylation Assay
          • NanoBRET TE Intracellular Kinase Assay
        • EGFR Drug Discovery
        • Kinase SubstrateFinder
        • KinaseFinder
        • Customized Kinase Drug Discovery
        • In Vivo Kinase Activity Models
        • Recombinant Kinase-related Products
      • Epigenetic Assays
        • Cell-based Epigenetic Assays
        • Reader Domain Assays
        • Methyltransferase Assays
        • Demethylase Assays
        • Histone Acetyltransferase Assays (HAT)
        • Histone Deacetylase (HDAC) & Sirtuin Assays
        • Isocitrate Dehydrogenase Assays (IDH)
        • Customized Epigenetic Drug Discovery
      • RAS-related Assays
      • Immune Checkpoint Assays
      • Targeted Protein Degradation Assays
      • PARP Assays
      • Phosphatase Assays
      • Protease Assays
      • Kinesin ATPase Assays
      • Apoptosis Pathway Assays
      • Metabolic Pathway Assays
        • Isocitrate Dehydrogenase Assays (IDH)
        • Carboxylase Assays
        • NAD(P)H Dehydrogenase (NQO)
        • Nucleotide Metabolism Pathway Assays
      • Phosphodiesterase Assays (PDE)
      • Ubiquitin-Proteasome Pathway Assays
      • Ion Channel Assays
      • GPCR Assays
      • Nuclear Receptor Assays
      • COVID-19-related Assays
        • SARS-CoV-2 S Protein and ACE2 Binding Assay
        • SARS-CoV-2-related Protease Assays
      • Additional Targets
        • Heat Shock Protein Assays
        • Replication-related Assays
      • Protein Production and Assay Development
      • Custom Antibody Services
      • Custom Peptide Services
    • box 2
      • Cell-based Assays
      • Target-specific Cell-based Assays
        • Kinase Assays
        • Intracellular PARP Assays
        • Epigenetic Assays
        • GPCR Assays
        • Ion Channel Assays
      • 2D Cell-based Assays
        • ProLiFiler™ Cancer Cell Panel Screening
        • Cell Proliferation and Viability Assays
        • Cell Death Assays
        • Migration Assay
      • 3D Cell-based Assays
        • 3D ProLiFiler™ Spheroid Cancer Cell Panel Screening
        • 3D Tumor Spheroid Assay
        • Soft Agar Assay
        • Angiogenesis Assay
      • Cell Line Generation
      • Assay Platforms
      • Biophysical Assays
      • Surface Plasmon Resonance (SPR)
      • Isothermal Titration Calorimetry (ITC)
      • Microscale Thermophoresis (MST)
      • Thermal Shift Assay (TSA)
      • Safety & Toxicology
      • In Vitro Safety Screening
      • Cardiac Safety Assessment
      • Cytochrome P450 Assays
      • Maximum-Tolerated Dose
    • Box 3
      • In Vivo Pharmacology
      • Xenograft Models
        • Subcutaneous Tumor Models
        • SubQperior Tumor Models
        • Orthotopic Tumor Models
        • Metastasis Models
      • In Vivo Hollow Fiber Model
      • In Vivo Kinase Activity Models
      • Immuno-Oncology Models
        • CAR-T Cell Therapy Platform
        • Humanized Xenograft Models
        • Humanized Syngeneic Models
        • Syngeneic Mouse Models
        • SubQperior Panel Screen
        • Mouse-derived Isograft Models (MDI)
        • Immunophenotyping
      • In Vivo PK/PD
      • Immuno-Oncology Platform
      • Immuno-Oncology Models
        • CAR-T Cell Therapy Platform
        • Humanized Xenograft Models
        • Humanized Syngeneic Models
        • Syngeneic Mouse Models
        • SubQperior™ Panel Screen
        • Mouse-derived Isograft Tumor Models (MDI)
        • Immunophenotyping
      • Immuno-Oncology Assays
        • T Cell Killing Assays
        • T Cell Assays
        • NK Cell Killing Assays
        • Immune Checkpoint Assays
        • Macrophage Cell-based Assays
      • Biomarker Discovery
      • Genetic Biomarkers
        • qPCR
        • Biomarker Analysis Tool
      • Protein Biomarkers
        • Flow Cytometry Applications
        • Multiplex Assays
        • ELISA / Western Blot / Alpha Technology
      • Phenotypic Biomarkers
        • Cell Death Mechanism
        • MOA Finder
      • Immunophenotyping
        • Immunohistochemistry and TMA
        • Immunophenotyping by Flow Cytometry
        • Multiplex Immune Assays
      • Bioprocessing
      • Bioassay and Potency Testing
  • Products
    • Box 1
      • Kinase-related Products
      • Active Protein Kinases
      • Active Lipid Kinases
      • Additional Kinase Variants
      • Recombinant Kinase Substrates
      • Custom Protein Production
      • Protein Production and Assay Development
      • Assay Kits
      • BromoMELT Assay Kit
    • Box 2
      • Epigenetic-related Products
      • All Epigenetic-related Products
      • Methyltransferase Proteins
      • Methyltransferase Substrates
      • Reader Domain Proteins
      • Deacetylase Proteins
      • Demethylase Proteins
      • DNA Repair Proteins
      • IDH Proteins
      • PARP Proteins
      • Assay Kits
      • Epigenetic Inhibitors
    • Box 3
      • Other Products
      • Ras-Related Proteins
      • NQO Proteins
      • Apoptosis Proteins
      • NUDIX & Nucleotide Pool Sanitation Proteins
      • Miscellaneous Proteins
      • Deiminase Proteins
      • SARS-CoV-2-related Proteins
  • Resources
    • box 1
      • Tools
      • Biomarker Analysis Tool
      • Kinase Mapper
      • MoA Finder
      • Tumor Microarray Gallery
    • box 2
      • Reading room
      • Resource Library
      • Blog
      • FAQ
  • Company
    • About us
    • Meet the Team
    • What people are saying
    • News and Press Releases
    • Events
    • Careers
  • Contact
  • English
  • 中文
  • Overview
  • Services
    • Target-specific Assays
      • Kinase Assays
        • Kinase Assay Services
        • Kinase Panel Screening
        • Cellular Kinase Assays
          • BaF3 Cell Proliferation Assay
          • Cellular Phosphorylation Assay
          • NanoBRET Intracellular Kinase Assay
        • EGFR Drug Discovery
        • Kinase SubstrateFinder
        • Kinase Finder
        • Customized Kinase Drug Discovery
        • In Vivo Kinase Activity Models
        • Recombinant Kinase-related Products
      • Epigenetic Assays
        • Cell-based Epigenetic Assays
        • Reader Domain Assays
        • Methyltransferase Assays
        • Demethylase Assays
        • Histone Acetyltransferase Assays (HAT)
        • Histone Deacetylase (HDAC) & Sirtuin Assays
        • Isocitrate Dehydrogenase Assays (IDH)
        • Customized Epigenetic Drug Discovery
      • RAS-related Assays
      • Immune Checkpoint Assays
      • Targeted Protein Degradation Assays
      • PARP Assays
      • Phosphatase Assays
      • Protease Assays
      • Kinesin ATPase Assays
      • Apoptosis Pathway Assays
      • Metabolic Pathway Assays
        • Isocitrate Dehydrogenase Assays (IDH)
        • Carboxylase Assays
        • NAD(P)H Dehydrogenase (NQO)
        • Nucleotide Metabolism Pathway Assays
      • Phosphodiesterase Assays (PDE)
      • Ubiquitin-Proteasome Pathway Assays
      • Ion Channel Assays
      • GPCR Assays
      • Nuclear Receptor Assays
      • COVID-19-related Assays
        • SARS-CoV-2 S Protein and ACE2 Binding Assay
        • SARS-CoV-2-related Protease Assays
      • Additional Targets
        • Heat Shock Protein Assays
        • Replication-related Assays
      • Protein Production and Assay Development
      • Custom Antibody Services
      • Custom Peptide Services
    • Cell-based Assays
      • Target-specific Cell-based Assays
        • Kinase Assays
        • Intracellular PARP Assays
        • Epigenetic Assays
        • GPCR Assays
        • Ion Channel Assays
      • 2D Cell-based Assays
        • ProLiFiler™ Cancer Cell Panel Screening
        • Cell Proliferation and Viability Assays
        • Cell Death Assays
        • Migration Assay
      • 3D Cell-based Assays
        • 3D Tumor Spheroid Assay
        • Soft Agar Assay
        • Angiogenesis Assay
      • Cell Line Generation
      • Assay Platforms
    • Biophysical Assays
      • Surface Plasmon Resonance (SPR)
      • Isothermal Titration Calorimetry (ITC)
      • Microscale Thermophoresis (MST)
      • Thermal Shift Assay (TSA)
    • Safety & Toxicology
      • In Vitro Safety Screening
      • Cardiac Safety Assessment
      • Cytochrome P450 Assays
      • Maximum-Tolerated Dose
    • In Vivo Pharmacology
      • Xenograft Models
      • In Vivo Hollow Fiber Model
      • In Vivo Kinase Activity Models
      • Immuno-Oncology Models
        • CAR-T Cell Therapy Platform
        • Humanized Xenograft Models
        • Humanized Syngeneic Models
        • Syngeneic Mouse Models
        • SubQperior™ Panel Screen
        • Mouse-derived Isograft Tumor Models (MDI)
        • Immunophenotyping
      • In Vivo PK/PD
    • Immuno-Oncology Platform
      • Immuno-Oncology Models
        • CAR-T Cell Therapy Platform
        • Humanized Xenograft Models
        • Humanized Syngeneic Models
        • Syngeneic Mouse Models
        • SubQperior™ Panel Screen
        • Mouse-derived Isograft Models (MDI)
        • Immunophenotyping
      • Immuno-Oncology Assays
        • T Cell Killing Assays
        • T Cell Assays
        • NK Cell Killing Assays
        • Immune Checkpoint Assays
        • Macrophage Cell-based Assays
    • Biomarker Discovery
      • Genetic Biomarkers
        • qPCR
        • Biomarker Analysis Tool
      • Protein Biomarkers
        • Flow Cytometry Applications
        • Multiplex Assays
        • ELISA / Western Blot / Alpha Technology
      • Phenotypic Biomarkers
        • Cell Death Mechanism
        • MOA Finder
      • Immunophenotyping
        • Immunohistochemistry and TMA
        • Immunophenotyping by Flow Cytometry
        • Multiplex Immune Assays
    • Bioprocessing
      • Bioassay and Potency Testing
  • Products
    • Kinase-related Products
      • Active Protein Kinases
      • Active Lipid Kinases
      • Additional Kinase Variants
      • Recombinant Kinase Substrates
    • Custom Protein Production
      • Protein Production and Assay Development
    • Assay Kits
      • BromoMELT Assay Kit
    • Epigenetic-related Products
      • All Epigenetic-related Products
      • Methyltransferase Proteins
      • Methyltransferase Substrates
      • Reader Domain Proteins
      • Deacetylase Proteins
      • Demethylase Proteins
      • DNA Repair Proteins
      • IDH Proteins
      • PARP Proteins
      • Assay Kits
      • Epigenetic Inhibitors
    • Other Products
      • Ras-Related Proteins
      • NQO Proteins
      • Apoptosis Proteins
      • NUDIX & Nucleotide Pool Sanitation Proteins
      • Miscellaneous Proteins
      • Deiminase Proteins
      • SARS-CoV-2-related Proteins
  • Resources
    • Tools
      • Biomarker Analysis Tool
      • Kinase Mapper
      • MoA Finder
    • Reading room
      • Resource Library
      • Blog
      • FAQ
  • Company
    • About us
    • Meet the Team
    • What people are saying
    • News and Press Releases
    • Events
    • Careers
  • Contact
Testing kinase inhibitors where it matters: Drug screening in intact cells

Testing kinase inhibitors where it matters: Drug screening in intact cells

by John Hewitt | Aug 13, 2024 | Blog

The ATP binding site of kinases represents both a golden opportunity and a formidable challenge for drug discovery teams. This well-defined pocket serves as the docking site for potent small-molecule inhibitors, making it an attractive target for drug development....

Reaction Biology to Present Data at AACR 2023 Showcasing Expansive Capabilities in Immuno-Oncology Drug Discovery and Development

by John Hewitt | Apr 12, 2023 | News

~ New Data will be Presented on the Company’s Innovative Assay Technologies, Preclinical Profiling Models and Proprietary Screening Platforms ~ ~ Reaction Biology will be at Booth #1527 in the AACR 2023 Exhibit Hall ~ Malvern, PA – April 12, 2023 – Reaction Biology...

Reaction Biology Selected for Participation in National Chemical Biology Consortium to Support Drug Discovery Utilizing Surface Plasmon Resonance (“SPR”) Technology

by John Hewitt | Dec 19, 2022 | News

Malvern, PA, December 19, 2022 – Reaction Biology Corporation (“Reaction”), an industry-leading provider of drug discovery services, today announced that it has been selected to participate as a Specialized Center in the Chemical Biology Consortium (CBC), the...

Reaction Biology Acquires Bioassay GmbH Increasing Large Molecule Capabilities Within Its Robust Portfolio of Drug Discovery and Development Services

by John Hewitt | Dec 2, 2022 | News

~ Bioassay GmbH, an Independent Contract Laboratory, Specializes in the Development, Validation and Routine Performance of Bioanalytical Assays ~ ~ Transaction Includes Acquisition of Bioassay GmbH Subsidiary, Peptide Specialty Laboratories GmbH, a Provider...

Reaction Biology and Vyant Bio Announce Closing of Definitive Agreement to Acquire U.S. Operations of Vyant Bio, Inc. Subsidiary

by John Hewitt | Nov 3, 2022 | News

~ Reaction Biology Acquires the Hershey, Pennsylvania-Based U.S. Operations of Vyant Bio Subsidiary vivoPharm PTY Ltd ~ ~ Transaction Expands Reaction Biology’s Capabilities to Provide Customers with Solutions in Both the Discovery and Development of New Drug...
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