by Reaction Biology | Jul 18, 2024 | Uncategorized
Macrophages: Double-Edged Swords in Cancer Macrophages are phagocytic cells that eliminate pathogens and modulate adaptive immunity through cytokine secretion. However, within the TME, they exhibit phenotypic plasticity, adopting either an anti-tumor M1 or pro-tumor...
by Reaction Biology | Jul 2, 2024 | Blog
The journey of kinase drug discovery is a fascinating tale, sparked by Nobel Laureate Edmund Fischer’s discovery of protein phosphorylation. With the identification of over 500 protein kinases in the human genome, their crucial role in cellular regulation became...
by Reaction Biology | Jun 20, 2024 | Uncategorized
The quest to develop new immunotherapeutic medicines relies heavily on effective preclinical research. Central to this research are in vivo animal tumor models with fully functional immune systems. Among these, syngeneic tumor models have emerged as powerful tools,...
by Reaction Biology | Jun 11, 2024 | Blog
The quest to develop new immunotherapeutic medicines relies heavily on effective preclinical research. Central to this research are in vivo animal tumor models with fully functional immune systems. Among these, syngeneic tumor models have emerged as powerful tools,...
by Reaction Biology | Jun 4, 2024 | Blog
Antibody-drug conjugates (ADCs) have emerged as a revolutionary approach to cancer therapy. These “smart bombs” combine the targeting power of monoclonal antibodies with the potent killing ability of cytotoxic drugs. Unlike traditional chemotherapy, which...
