| Target | HGNC Reference | Uniprot # | Additional Synonyms | Assay Format | Protein_Lipid | Bi-weekly | Datasheet |
|---|---|---|---|---|---|---|---|
| ABL1 | ABL1 | P00519 | ABL, JTK7, p150, c-ABL, v-abl | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| ABL1 (E255K) | ABL1 (E255K) | P00519 | ABL, JTK7, p150, c-ABL, v-abl | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ABL1 (E255V) | ABL1 (E255V) | P00519 | ABL, JTK7, p150, c-ABL, v-abl | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ABL1 (F317I) | ABL1 (F317I) | P00519 | ABL, JTK7, p150, c-ABL, v-abl | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ABL1 (F317L) | ABL1 (F317L) | P00519 | ABL, JTK7, p150, c-ABL, v-abl | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ABL1 (G250E) | ABL1 (G250E) | P00519 | ABL, JTK7, p150, c-ABL, v-abl | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ABL1 (H396P) | ABL1 (H396P) | P00519 | ABL, JTK7, p150, c-ABL, v-abl | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ABL1 (M351T) | ABL1 (M351T) | P00519 | ABL, JTK7, p150, c-ABL, v-abl | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ABL1 (Q252H) | ABL1 (Q252H) | P00519 | ABL, JTK7, p150, c-ABL, v-abl | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ABL1 (T315I) | ABL1 (T315I) | P00519 | ABL, JTK7, p150, c-ABL, v-abl | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ABL1 (V299L) | ABL1 (V299L) | P00519 | ABL, JTK7, p150, c-ABL, v-abl | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ABL1 (Y253F) | ABL1 (Y253F) | P00519 | ABL, JTK7, p150, c-ABL, v-abl | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ABL1 (Y253H) | ABL1 (Y253H) | P00519 | ABL, JTK7, p150, c-ABL, v-abl | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ABL2/ARG | ABL2 | P42684 | ABLL, ARG | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| ACK1 | TNK2 | Q07912 | ACK, p21cdc42Hs, Activated CDC42 kinase 1 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| AKT1 | AKT1 | P31749 | PKB, RAC, PRKBA, RAc-ALPHA | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| AKT1 (E17K) | AKT1 (E17K) | P31749 | PKB, RAC, PRKBA, RAc-ALPHA | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| AKT2 | AKT2 | P31751 | PRKBB, PKBBETA, RAc-BETA | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| AKT2 (E17K) | AKT2 (E17K) | P31751 | PRKBB, PKBBETA, RAc-BETA | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| AKT3 | AKT3 | Q9Y243 | PKBG, PKB gamma, PRKBG, RAC-gamma, RAC-PK-gamma, STK-2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| AKT3 (E17K) | AKT3 (E17K) | Q9Y243 | PKBG, PKB gamma, PRKBG, RAC-gamma, RAC-PK-gamma, STK-2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| AKT3 (G171R) | AKT3 (G171R) | Q9Y243 | PKBG, PKB gamma, PRKBG, RAC-gamma, RAC-PK-gamma, STK-2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK | ALK | Q9UM73 | CD246, NBLST3 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| ALK (C1156Y) | ALK (C1156Y) | Q9UM73 | CD246, NBLST3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK (F1174L) | ALK (F1174L) | Q9UM73 | CD246, NBLST3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK (F1174L)-EML4 | ALK (F1174L)-EML4 | A6P4T4 | CD246, NBLST3, EML4-ALK (F1174L) | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK (F1174L)-NPM1 | ALK (F1174L)-NPM1 | P06748, Q9UM73 | CD246, NBLST3, NPM1-ALK (F1174L) | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK (F1174S) | ALK (F1174S) | Q9UM73 | CD246, NBLST3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK (G1202R) | ALK (G1202R) | Q9UM73 | CD246, NBLST3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK (G1269A) | ALK (G1269A) | Q9UM73 | CD246, NBLST3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK (G1269S) | ALK (G1269S) | Q9UM73 | CD246, NBLST3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK (L1152R) | ALK (L1152R) | Q9UM73 | CD246, NBLST3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK (L1196M) | ALK (L1196M) | Q9UM73 | CD246, NBLST3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK (L1196M/G1202R) | ALK (L1196M/G1202R) | Q9UM73 | CD246 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK (R1275Q) | ALK (R1275Q) | Q9UM73 | CD246, NBLST3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK (S1206R) | ALK (S1206R) | Q9UM73 | CD246, NBLST3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK (T1151-L1152insT) | ALK (T1151-L1152insT) | Q9UM73 | CD246, NBLST3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK (T1151M) | ALK (T1151M) | Q9UM73 | CD246, NBLST3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK-EML4 (Eex13Aex20) | ALK-EML4 | Q9HC35, Q9UM73 | CD246, EMAP-4 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK-EML4 (Eex14Aex20) | ALK-EML4 | Q9HC35, Q9UM73 | CD246, EMAP-4 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK-EML4 (Eex20Aex20) | ALK-EML4 | Q9HC35, Q9UM73 | CD246, EMAP-4 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK-EML4 (Eex6Aex20) | ALK-EML4 | Q9HC35, Q9UM73 | CD246, EMAP-4 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK-KIF5B (Kex24Aex20) | ALK-KIF5B | P33176, Q9UM73 | CD246, NBLST3, KIF5B-ALK | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK-KLC1 (Kex8Aex20) | ALK-KLC1 | Q07866, Q9UM73 | CD246, NBLST3, KCL1-ALK | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK-NPM1 | ALK-NPM1 | P06748, Q9UM73 | CD246, NBLST3, NPM1-ALK | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK-STRN (Sex3Aex20) | ALK-STRN | O43815, Q9UM73 | CD246, Striatin | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK-TFG | ALK-TFG | Q92734, Q9UM73 | CD246, NBLST3, TFG-ALK | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK-TFG (Tex4Aex20) | ALK-TFG | Q92734, Q9UM73 | CD246, NBLST3, TFG-ALK | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK-TPM1 | ALK-TPM1 | P09493, Q9UM73 | CD246, NBLST3, TPM1-ALK | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK-TPM3 | ALK-TPM3 | P06753, Q9UM73 | CD246, NBLST3, TPM3-ALK | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK1/ACVRL1 | ACVRL1 | P37023 | ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| ALK2 (Q207D) | ACVR1 (Q207D) | Q04771 | ACTRI, ACVRLK2, ALK2, SKR1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK2 (R206H) | ACVR1 (R206H) | Q04771 | ACTRI, ACVRLK2, ALK2, SKR1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ALK2/ACVR1 | ACVR1 | Q04771 | ACTRI, ACVRLK2, ALK2, SKR1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| ALK3/BMPR1A | BMPR1A | P36894 | SKR5, CD292, ALK3, ACVRLK3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| ALK4/ACVR1B | ACVR1B | P36896 | ACTRIB, ACVRLK4, ALK4, SKR2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| ALK5/TGFBR1 | TGFBR1 | P36897 | ALK5, ACVRLK4 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| ALK6/BMPR1B | BMPR1B | O00238 | ALK6, CDw293 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| AMPK (A1/B1/G1) | PRKAA1-PRKAB1-PRKAG1 | Q13131, Q9Y478, P54619 | AMPK (A1/B1/G1) | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| AMPK (A1/B1/G2) | PRKAA1-PRKAB1-PRKAG2 | Q13131, Q9Y478, Q9UGJ0 | AMPK (A1/B1/G2) | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| AMPK (A1/B1/G3) | PRKAA1-PRKAB1-PRKAG3 | Q13131, Q9Y478, Q9UGI9 | AMPK (A1/B1/G3) | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| AMPK (A1/B2/G1) | PRKAA1-PRKAB2-PRKAG1 | Q13131, O43741, P54619 | AMPK (A1/B2/G1) | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| AMPK (A1/B2/G2) | PRKAA1-PRKAB2-PRKAG2 | Q13131, O43741, Q9UGJ0 | AMPK (A1/B2/G2) | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| AMPK (A1/B2/G3) | PRKAA1-PRKAB2-PRKAG3 | Q13131, O43741, Q9UGI9 | AMPK (A1/B2/G3) | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| AMPK (A2/B1/G1) | PRKAA2-PRKAB1-PRKAG1 | P54646, Q9Y478, P54619 | AMPK (A2/B1/G1) | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| AMPK (A2/B1/G2) | PRKAA2-PRKAB1-PRKAG2 | P54646, Q9Y478, Q9UGJ0 | AMPK (A2/B1/G2) | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| AMPK (A2/B1/G3) | PRKAA2-PRKAB1-PRKAG3 | P54646, Q9Y478, Q9UGI9 | AMPK (A2/B1/G3) | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| AMPK (A2/B2/G1) | PRKAA2-PRKAB2-PRKAG1 | P54646, O43741, P54619 | AMPK (A2/B2/G1) | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| AMPK (A2/B2/G2) | PRKAA2-PRKAB2-PRKAG2 | P54646, O43741, Q9UGJ0 | AMPK (A2/B2/G2) | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| AMPK (A2/B2/G3) | PRKAA2-PRKAB2-PRKAG3 | P54646, O43741, Q9UGI9 | AMPK (A2/B2/G3) | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| ARAF | ARAF (Y301D/Y302D) | P10398 | A-RA, ARAF1, PKS2, RAFA1, ARAF YDYD | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| ARK5/NUAK1 | NUAK1 | O60285 | KIAA0537, ARK5 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| ASK1/MAP3K5 | MAP3K5 | Q99683 | ASK1, MAPKKK5, MEKK5 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| ATM* | ATM | Q13315 | TEL1, TELO1 | HTRF | Protein kinase | Not included in any panel | HTRF |
| Aurora A | AURKA | O14965 | AurA, AIK, ARK1, AURA, BTAK, STK15, AuroraA, Aurora A | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| Aurora B | AURKB | Q96GD4 | AurB, AIK2, AIM1, ARK2, AurB, IPL1, STK5, AuroraB, Aurora B | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| Aurora B (G160L) | AURKB (G160L) | Q96GD4 | AurB, AIK2, AIM1, ARK2, AurB, IPL1, STK5, AuroraB, Aurora B | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| Aurora C | AURKC | Q9UQB9 | AurC, AIE2, AIK3, STK13, Aurora C, AuroraC | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| AXL | AXL | P30530 | EC, UFO | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| AXL (R499C) | AXL (R199C) | P30530 | EC, UFO | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BLK | BLK | P51451 | BLK | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| BMPR2 | BMPR2 | Q13873 | BMPR-II, BMPR3, BMR2, BRK-3, PPH1, T-ALK | HotSpot™ | ADP-Glo | Probe-displacement | Protein kinase | Not included in any panel | HotSpotᵇ, ADP-Glo, Probe-displacement |
| BMX/ETK | BMX | P51813 | ETK, PSCTK2, PSCTK3 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| BRAF | BRAF | P15056 | B-Raf, B-raf-1, BRAF1, RAFB1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| BRAF (d485-489/P490Y) | BRAF (d485-489/P490Y) | P15056 | B-Raf, B-raf-1, BRAF1, RAFB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BRAF (G464V) | BRAF (G464V) | P15056 | B-Raf, B-raf-1, BRAF1, RAFB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BRAF (G469A) | BRAF (G469A) | P15056 | B-Raf, B-raf-1, BRAF1, RAFB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BRAF (K601E) | BRAF (K601E) | P15056 | B-Raf, B-raf-1, BRAF1, RAFB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BRAF (L597V) | BRAF (L597V) | P15056 | B-Raf, B-raf-1, BRAF1, RAFB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BRAF (R506_K507insVLR) | BRAF (R506_K507insVLR) | P15056 | B-Raf, B-raf-1, BRAF1, RAFB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BRAF (T599_V600insT) | BRAF (T599_V600insT) | P15056 | B-Raf, B-raf-1, BRAF1, RAFB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BRAF (V599E) | BRAF (V600E) | P15056 | B-Raf, B-raf-1, BRAF1, RAFB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BRAF (V600A) | BRAF (V600A) | P15056 | B-Raf, B-raf-1, BRAF1, RAFB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BRAF (V600D) | BRAF (V600D) | P15056 | B-Raf, B-raf-1, BRAF1, RAFB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BRAF (V600K) | BRAF (V600K) | P15056 | B-Raf, B-raf-1, BRAF1, RAFB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BRAF-FAM131B | BRAF-FAM131B | Q86XD5, P15056 | B-Raf, B-raf-1, BRAF1, RAFB1, FAM131B-BRAF | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BRAF-KIAA1549 (Kex15Bex9) | BRAF-KIAA1549 (Kex15Bex9) | Q9HCM3, P15056 | B-Raf, B-raf-1, BRAF1, RAFB1, KIAA1549-BRAF | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BRAF-KIAA1549 (Kex16Bex9) | BRAF-KIAA1549 (Kex16Bex9) | Q9HCM3, P15056 | B-Raf, B-raf-1, BRAF1, RAFB1, KIAA1549-BRAF | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BRAF-SRGAP3 (Sex12Bex9) | BRAF-SRGAP3 | O43295, P15056 | B-Raf, B-raf-1, BRAF1, RAFB1, SRGAP3-BRAF | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BRK | PTK6 | Q13882 | BRK | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| BRSK1 | BRSK1 | Q8TDC3 | KIAA1811 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| BRSK2 | BRSK2 | Q8IWQ3 | C11orf7, FLJ41362, HUSSY-12, PEN11B, SAD1, STK29 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| BTK | BTK | Q06187 | AGMX1, AT, ATK, BPK, PSCTK1 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| BTK (C481S) | BTK (C481S) | Q06187 | AGMX1, AT, ATK, BPK, PSCTK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BTK (E41K) | BTK (E41K) | Q06187 | AGMX1, AT, ATK, BPK, PSCTK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BTK (P190K) | BTK (P190K) | Q06187 | AGMX1, AT, ATK, BPK, PSCTK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BTK (T474I) | BTK (T474I) | Q06187 | AGMX1, AT, ATK, BPK, PSCTK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| BTK (Y485F) | BTK (Y485F) | Q06187 | AGMX1, AT, ATK, BPK, PSCTK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT | KIT | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| c-KIT (A829P) | KIT (A829P) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (d557-558) | KIT (d557-558) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (D816E) | KIT (D816E) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (D816F) | KIT (D816F) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (D816H) | KIT (D816H) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (D816I) | KIT (D816I) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (D816V) | KIT (D816V) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (D816Y) | KIT (D816Y) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (D820E) | KIT (D820E) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (D820Y) | KIT (D820Y) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (K642E) | KIT (K642E) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Not included in any panel | HotSpotᵇ |
| c-KIT (T670I) | KIT (T670I) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (V559A) | KIT (V559A) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (V559D) | KIT (V559D) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (V559D/T670I) | KIT (V559D/T670I) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (V559D/V654A) | KIT (V559D/V654A) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (V560G) | KIT (V560G) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (V560G/D816V) | KIT (V560G/D816V) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (V560G/N822K) | KIT (V560G/N822K) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (V654A) | KIT (V654A) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (Y823D) | KIT (Y823D) | P10721 | C-Kit, PBT, CD117, SCFR, | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MER | MERTK | Q12866 | MER, MER-PEN, RP38, c-MER | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| c-MER (A708S) | MERTK (A708S) | Q12866 | MER, MER-PEN, RP38, c-MER | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET | MET | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| c-MET (D1228A) | MET (D1228A) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (D1228G) | MET (D1228G) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (D1228H) | MET (D1228H) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (D1228N) | MET (D1228N) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (D1228V) | MET (D1228V) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (D1228Y) | MET (D1228Y) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (DelEx14) | MET (DelEx14) | P08581 | c-Met, HGFR, MET | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (F1200I) | MET (F1200I) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (G1163R) | MET (G1163R) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (H1094L) | MET (H1094L) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (H1094Y) | MET (H1094Y) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (K1244R) | MET (K1244R) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (L1195F) | MET (L1195F) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (L1195V) | MET (L1195V) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (M1250I) | MET (M1250I) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (M1250T) | MET (M1250T) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (P991S) | MET (P991S) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (R970C) | MET (R970C) | P08581 | c-Met, HGFR, MET | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (T1173I) | MET (T1173I) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (T992I) | MET (T992I) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (V1092I) | MET (V1092I) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (Y1230A) | MET (Y1230A) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (Y1230C) | MET (Y1230C) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (Y1230D) | MET (Y1230D) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (Y1230H) | MET (Y1230H) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (Y1230S) | MET (Y1230S) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (Y1235D) | MET (Y1235D) | P08581 | c-MET, HGFR, RCCP2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET-KIF5B (Kex24Mex14) | MET-KIF5B | P33176, P08581 | c-MET, HGFR, RCCP2, KIF5B-MET | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET-TFG (Tex5Mex15) | MET-TFG | Q92734, P08581 | c-MET, HGFR, RCCP2, TGF-MET | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-SRC | SRC | P12931 | ASV, SRC1, c-SRC, p60-Src | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| c-SRC (T341M) | SRC (T341M) | P12931 | ASV, SRC1, c-SRC, p60-Src | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-SRC (Y530F) | SRC (Y530F) | P12931 | ASV, SRC1, c-SRC, p60-Src | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| CAMK1a | CAMK1 | Q14012 | CAMK1-PEN, CAMKI | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| CAMK1b | PNCK | Q6P2M8 | CAMK1b, MGC45419 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CAMK1d | CAMK1D | Q8IU85 | CKLiK, CaM-K1, CaMKID | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CAMK1g | CAMK1G | Q96NX5 | CLICKIII, VWS1, dJ272L16.1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CAMK2a | CAMK2A | Q9UQM7 | CAMKA, KIAA0968 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CAMK2b | CAMK2B | Q13554 | CAM2, CAMK2, CAMKB, MGC29528 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CAMK2d | CAMK2D | Q13557 | CAMKD, MGC44911, CaMKII delta | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CAMK2g | CAMK2G | Q13555 | CAMK, CAMK-II, CAMKG, MGC26678 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CAMK4 | CAMK4 | Q16566 | CaMK-GR, MGC36771 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CAMKK1 | CAMKK1 | Q8N5S9 | CAMKKA, DKFZp761M0423, MGC34095 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CAMKK2 | CAMKK2 | Q96RR4 | CAMKK, CAMKKB, KIAA0787, MGC15254 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDC7/DBF4 | CDC7-DBF4 | O00311, Q9UBU7 | CDC7L1, HsCdc7, HsCDC7, Hsk1, huCdc7 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK1/cyclin A | CDK1-CCNA2 | P06493, P20248 | CDC2, p34 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK1/cyclin B | CDK1-CCNB1 | P06493 | CDC2, p34 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| CDK1/cyclin E | CDK1-CCNE1 | P06493, P24864 | CDC2, p34 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK12 (R722C)/cyclin K | CDK12 (R722C)-CCNK | Q9NYV4, O75909 | CRKRS, CRK7 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| CDK12/cyclin K | CDK12-CCNK | Q9NYV4, O75909 | CRKRS, CRK7 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK13/cyclin K | CDK13-CCNK | Q14004, O75909 | CDC2L, CDC2L5, CHED | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK14/cyclin Y (PFTK1) | CDK14-CCNY | O94921, Q8ND76 | PFTAIRE1, PFTK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK15/Cyclin A2 | CDK15-CCNA2 | Q96Q40, P20248 | Cyclin-dependent kinase 15, Cell division protein kinase 15, PFTK2, CCNA2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK15/Cyclin B1 | CDK15-CCNB1 | Q96Q40, P14635 | PFTK2, CCNB1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK16/cyclin Y | CDK16-CCNY | Q00536, Q8ND76 | PCTAIRE1, PCTAIRE, PCTGAIRE, PCTK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK17/cyclin Y | CDK17-CCNY | Q00537, Q8ND76 | PCTAIRE2, PCTK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK18/cyclin Y | CDK18-CCNY | Q07002, Q8ND76 | PCTAIRE, PCTAIRE3, PCTK3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK19/cyclin C | CDK19-CCNC | Q9BWU1, P24863 | CDC2L6, CDK11 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK2/cyclin A | CDK2-CCNA2 | P24941, P20248 | p33 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK2/cyclin A1 | CDK2-CCNA1 | P24941, P78396 | p33 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK2/cyclin E | CDK2-CCNE1 | P24941, P24864 | p33 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK2/cyclin E2 | CDK2-CCNE2 | P24941, O96020 | p33 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK2/cyclin O | CDK2-CCNO | P24941, P22674 | p33 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK3/Cyclin C | CDK3-CCNC | Q00526, P24863 | Cyclin-dependent kinase 3, CCNC | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK3/cyclin E | CDK3-CCNE1 | Q00526, P24864 | CDKN3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK3/cyclin E2 | CDK3-CCNE2 | Q00526, O96020 | CDKN3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK4/cyclin D1 | CDK4-CCND1 | P11802, P24385 | CMM3, PSK-J3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| CDK4/cyclin D2 | CDK4-CCND2 | P11802, P30279 | CMM3, PSK-J3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK4/cyclin D3 | CDK4-CCND3 | P11802, P30281 | CMM3, PSK-J3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK5/p25 | CDK5-CDK5R1 (p25) | Q00535, Q15078 | PSSALRE | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK5/p35 | CDK5-CDK5R1 | Q00535, Q15078 | PSSALRE | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK6/cyclin D1 | CDK6-CCND1 | Q00534, P24385 | PLSTIRE | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK6/cyclin D2 | CDK6-CCND2 | Q00534, P30279 | PLSTIRE | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK6/cyclin D3 | CDK6-CCND3 | Q00534, P30281 | PLSTIRE | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK7/cyclin H/MNAT1 | CDK7-CCNH-MNAT1 | P50613, P51946, P51948 | CAK1, CDKN7, STK1, p39MO15 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| CDK8/cyclin C | CDK8-CCNC | P49336, P24863 | K35 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK9/cyclin K | CDK9-CCNK | P50750, O75909 | C-2k, CDC2L4, PITALRE, TAK, CDC2-related kinase | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK9/cyclin T1 | CDK9-CCNT1 | P50750, O60563 | C-2k, CDC2L4, PITALRE, TAK, CDC2-related kinase | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CDK9/cyclin T2 | CDK9-CCNT2 | P50750, O60583 | C-2k, CDC2L4, PITALRE, TAK, CDC2-related kinase | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| CHK1 | CHEK1 | O14757 | CHEK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| CHK2 | CHEK2 | O96017 | CDS1, HuCds1, PP1425, RAD53, bA444G7 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CHK2(I157T) | CHEK2 (I157T) | O96017 | CDS1, HuCds1, PP1425, RAD53, bA444G7 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| CK1a1 | CSNK1A1 | P48729 | CK1, HLCDGP1, PRO2975, CK1-alpha1, CK1alpha1, CK1a1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| CK1a1 (E42C) | CK1a1 (E42C) | P48729 | CKI-alpha, CK1, KC1A, CSNK1A1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| CK1a1 (I35C) | CK1a1 (I35C) | P48729 | CKI-alpha, CK1, KC1A, CSNK1A1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| CK1a1L | CSNK1A1L | Q8N752 | CK1-alpha1 like | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CK1d | CSNK1D | P48730 | HCKID, CK1-delta, CK1d, CK1delta | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CK1epsilon | CSNK1E | P49674 | CKIe, HCKIE, MGC10398, CK1-epsilon | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CK1epsilon (R178C) | CSNK1E (R178C) | P49674 | CKIe, HCKIE, MGC10398, CK1-epsilon | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| CK1g1 | CSNK1G1 | Q9HCP0 | CK1-gamma1, CK1gamma1, CK1g1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| CK1g2 | CSNK1G2 | P78368 | CK1g2, CK1-gamma2, CK1gamma2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CK1g3 | CSNK1G3 | Q9Y6M4 | CK1-gamma3, CK1gamma3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CK2a | CSNK2A1 | P68400 | CKII, CK2A1, CK2-alpha1, CK2alpha1, CK2a | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| CK2a2 | CSNK2A2 | P19784 | CK2-alpha2, CK2alpha2, CK2a2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CLK1 | CLK1 | P49759 | CLK, CLK/STY | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CLK2 | CLK2 | P49760 | MGC61500, hCLK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| CLK3 | CLK3 | P49761 | PHCLK3, PHCLK3/152, CDc-like kinase 3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CLK4 | CLK4 | Q9HAZ1 | DKFZp686A20267, CDc-like kinase 4 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| COT1/MAP3K8 | MAP3K8 | P41279 | COT1, EST, ESTF, TPL2, Tpl-2, COT | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| CSK | CSK | P41240 | CSK | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| CTK/MATK | MATK | P42679 | CHK, CTK, DKFZp434N1212, HHYLTK, HYL, Lsk, MGC1708, MGC2101 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| DAPK1 | DAPK1 | P53355 | DAPK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| DAPK2 | DAPK2 | Q9UIK4 | DRP-1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| DCAMKL1 | DCLK1 | O15075 | DCLK, KIAA0369 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| DCAMKL2 | DCLK2 | Q8N568 | DCDC3, DCK2, MGC45428, KIAA0369 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| DDR1 | DDR1 | Q08345 | CAK, CD167, DDR, EDDR1, MCK10, NEP | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| DDR2 | DDR2 | Q16832 | MIG20a, NTRKR3, TKT, TYRO10 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| DDR2 (N456S) | DDR2 (N456S) | Q16832 | MIG20a, NTRKR3, TKT, TYRO10 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| DDR2 (T654M) | DDR2 (T654M) | Q16832 | MIG20a, NTRKR3, TKT, TYRO10 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| DGKA | DGKA | P23743 | DAGK1, DAGK, DGK-alpha | ADP-Glo | Lipid kinase | Bi-weekly DGK Panel | ADP-Glo |
| DGKB | DGKB | Q9Y6T7 | DAGK2, KIAA0718, DGK-beta | ADP-Glo | Lipid kinase | Bi-weekly DGK Panel | ADP-Glo |
| DGKD | DGKD | Q16760 | DGK-delta, KIAA0145 | ADP-Glo | Lipid kinase | Bi-weekly DGK Panel | ADP-Glo |
| DGKE | DGKE | P52429 | DAGK5, DGK-epsilon | ADP-Glo | Lipid kinase | Bi-weekly DGK Panel | ADP-Glo |
| DGKG | DGKG | P49619 | DAGK3, DGK-gamma | ADP-Glo | Lipid kinase | Bi-weekly DGK Panel | ADP-Glo |
| DGKH | DGKH | Q86XP1 | DGK-eta | ADP-Glo | Lipid kinase | Bi-weekly DGK Panel | ADP-Glo |
| DGKI | DGKI | O75912 | DGK-iota | ADP-Glo | Lipid kinase | Bi-weekly DGK Panel | ADP-Glo |
| DGKK | DGKK | Q5KSL6 | DGK-kappa | ADP-Glo | Lipid kinase | Bi-weekly DGK Panel | ADP-Glo |
| DGKQ | DGKQ | P52824 | DAGK4, DGK-theta | ADP-Glo | Lipid kinase | Bi-weekly DGK Panel | ADP-Glo |
| DGKZ | DGKZ | Q13574 | DAGK6, DGK-zeta | ADP-Glo | Lipid kinase | Bi-weekly DGK Panel | ADP-Glo |
| DLK/MAP3K12 | MAP3K12 | Q12852 | DLK | HotSpot™ | Protein kinase | Not included in any panel | HotSpotᵇ |
| DMPK | DMPK | Q09013 | DMPK1, DM, DM1, DM1PK, DMK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| DMPK2/CDC42BPG | CDC42BPG | Q6DT37 | DMPK2, HSMDPKIN, KAPPA-200, | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| DNA-PK | PRKDC | P78527 | DNPK1, HYRC, p350, DNAPK, DNA-PK | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| DRAK1/STK17A | STK17A | Q9UEE5 | DRAK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| DYRK1/DYRK1A | DYRK1A | Q13627 | DYRK, DYRK1, HP86, MNB, MNBH | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| DYRK1B | DYRK1B | Q9Y463 | MIRK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| DYRK2 | DYRK2 | Q92630 | DYRK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| DYRK3 | DYRK3 | O43781 | DYRK5, RED, REDK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| DYRK4 | DYRK4 | Q9NR20 | DYRK4 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| EEF2K | EEF2K | O00418 | HSU93850, MGC45041, eEF-2K | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| EGFR | EGFR | P00533 | ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| EGFR (A763_Y764insFHEA) | EGFR (A763_Y764insFHEA) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (A763_Y764insFQEA) | EGFR (A763_Y764insFQEA) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (A767_S768insTLA) | EGFR (A767_S768insTLA) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (C775S/T790M/L858R) | EGFR (C775S/T790M/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (C797A) | EGFR (C797A) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (C797G/L858R) | EGFR (C797G/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (C797S) | EGFR (C797S) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (C797S/L858R) | EGFR (C797S/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d746) | EGFR (d746) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d746-750) | EGFR (d746-750) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d746-750/C775S /T790M /L858R) | EGFR (d746-750/C775S/T790M/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d746-750/C797A) | EGFR (d746-750/C797A) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d746-750/C797S) | EGFR (d746-750/C797S) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d746-750/G724S) | EGFR (d746-750/G724S) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d746-750/S768I) | EGFR (d746-750/S768I) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d746-750/T790M) | EGFR (d746-750/T790M) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d746-750/T790M/C797S) | EGFR (d746-750/T790M/C797S) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d746-750/T790M/C797S/L858R) | EGFR (d746-750/T790M/C797S/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d746-750/T790M/L792F) | EGFR (d746-750/T790M/L792F) | P00533 | EGFR, ERBB1, HER1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d746-750/T790M/L792H) | EGFR (d746-750/T790M/L792H) | P00533 | EGFR, ERBB1, HER1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d746-750/T790M/L798I) | EGFR (d746-750/T790M/L798I) | P00533 | EGFR, ERBB1, HER1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d746-750/T790M/L858R) | EGFR (d746-750/T790M/L858R) | P00533 | EGFR, ERBB1, HER1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d747-749) | EGFR (d747-749) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d747-749/A750P) | EGFR (d747-749/A750P) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d747-752/P753S) | EGFR (d747-752/P753S) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (d752-759) | EGFR (d752-759) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (D761Y) | EGFR (D761Y) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (D770_N771insNPG) | EGFR (D770_N771insNPG) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (D770_N771insNPG/T790M) | EGFR (D770_N771insNPG/T790M) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (D770GY) | EGFR (D770GY) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (G719C) | EGFR (G719C) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (G719D) | EGFR (G719D) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (G719S) | EGFR (G719S) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (K716A) | EGFR (K716A) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (K716A/C797S/L858R) | EGFR (K716A/C797S/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (K716A/T790M/C797S/L858R) | EGFR (K716A/T790M/C797S/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (K716Q/L718Q) | EGFR (K716Q/L718Q) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (K728A) | EGFR (K728A) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (K728A/T790M/C797S/L858R) | EGFR (K728A/T790M/C797S/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (L718Q) | EGFR (L718Q) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (L747S) | EGFR (L747S) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (L792F) | EGFR (L792F) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (L792F/L858R) | EGFR (L792F/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (L792H) | EGFR (L792H) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (L792H/C797S/L858R) | EGFR (L792H/C797S/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (L792H/L858R) | EGFR (L792H/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (L858R) | EGFR (L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (L858R/T790M) | EGFR (T790M/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (L861Q) | EGFR (L861Q) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (N771_P772insH) | EGFR (N771_P772insH) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (R999A) | EGFR (R999A) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (T790M) | EGFR (T790M) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (T790M/C797G/L858R) | EGFR (T790M/C797G/L858R) | P00533 | EGFR, ErbB-1, HER1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (T790M/C797S /L858R) | EGFR (T790M/C797S/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (T790M/C797S) | EGFR (T790M/C797S) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (T790M/L792F/C797S/L858R) | EGFR (T790M/L792F/C797S/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (T790M/L792F/L858R) | EGFR (T790M/L792F/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (T790M/L792H/C797S/L858R) | EGFR (T790M/L792H/C797S/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (T790M/L792H/L858R) | EGFR (T790M/L792H/L858R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (V769_D770insGE) | EGFR (V769_D770insGE) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EIF2AK1/HRI | EIF2AK1 | Q9BQI3 | HCR, HRI, EIF2AK1 | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| EIF2AK2/PKR | EIF2AK2 | P19525 | PKR, PRKR | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| EIF2AK3/PERK | EIF2AK3 | Q9NZJ5 | DKFZp781H1925, PEK, PERK, WRS | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| EIF2AK4/GCN2 | EIF2AK4 | Q9P2K8 | GCN2 | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| EPHA1 | EPHA1 | P21709 | EPH, EPHT, EPHT1 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| EPHA2 | EPHA2 | P29317 | ECK | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| EPHA3 | EPHA3 | P29320 | ETK, ETK1, HEKECK, HEK4, TYRO4 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| EPHA4 | EPHA4 | P54764 | HEK8, SEK, TYRO1 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| EPHA5 | EPHA5 | P54756 | CEK7, EHK1,HEK7, | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| EPHA6 | EPHA6 | Q9UF33 | EHK2, EHK-2, EPA6 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| EPHA7 | EPHA7 | Q15375 | EHK3, HEK11 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| EPHA8 | EPHA8 | P29322 | EEK, HEK3, KIAA1459 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| EPHB1 | EPHB1 | P54762 | ELK, NET, Hek6, EPHT2 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| EPHB2 | EPHB2 | P29323 | DRT, ERK, Hek5, EPHT3, Tyro5 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| EPHB3 | EPHB3 | P54753 | ETK2, HEK2, TYRO6 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| EPHB4 | EPHB4 | P54760 | HTK, MYK1, TYRO11 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| ERBB2 (A775_G776insYVMA) | ERBB2 (A775_G776insYVMA) | P04626 | NEU, NGL, HER2, TKR1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ERBB2 (D769H) | ERBB2 (D769H) | P04626 | NEU, NGL, HER2, TKR1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ERBB2 (D769Y) | ERBB2 (D769Y) | P04626 | NEU, NGL, HER2, TKR1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ERBB2 (P1170A) | ERBB2 (P1170A) | P04626 | NEU, NGL, HER2, TKR1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ERBB2 (P780-Y781insGSP) | ERBB2 (P780-Y781insGSP) | P04626 | NEU, NGL, HER2, TKR1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ERBB2 (R896C) | ERBB2 (R896C) | P04626 | NEU, NGL, HER2, TKR1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ERBB2 (V777_G778insCG) | ERBB2 (V777_G778insCG) | P04626 | NEU, NGL, HER2, TKR1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ERBB2 (V777L) | ERBB2 (V777L) | P04626 | NEU, NGL, HER2, TKR1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ERBB2/HER2 | ERBB2 | P04626 | NEU, NGL, HER2, TKR1 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| ERBB4/HER4 | ERBB4 | Q15303 | HER4 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| ERK1/MAPK3 | MAPK3 | P27361 | ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| ERK2/MAPK1 | MAPK1 | P28482 | ERK2, ERT1, P42MAPK, PRKM1, | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| ERK5/MAPK7 CD* | MAPK7 (CD) | Q13164 | BMK1, PRKM7 | HotSpot™ | Protein kinase | Not included in any panel | HotSpot |
| ERK5/MAPK7 FL | MAPK7 | Q13164 | BMK1, PRKM7 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| ERK7/MAPK15 | MAPK15 | Q8TD08 | ERK8 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| ERN1 (R727A) | ERN1 (R727A) | O75460 | IRE1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ERN1 (R728A) | ERN1 (R728A) | O75460 | IRE1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ERN1/IRE1 | ERN1 | O75460 | IRE1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| ERN1/IRE1 (R727A/R728A) | ERN1/IRE1 (R727A/R728A) | O75460 | IRE1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ERN2/IRE2 | ERN2 | Q76MJ5 | IRE2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| FAK/PTK2 | PTK2 | Q05397 | FAK, FADK | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| FER | FER | P16591 | TYK3, c-FER, p94-FER | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| FES/FPS | FES | P07332 | FPS | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| FGFR1 | FGFR1 | P11362 | H2, H3, H4, H5, CEK, FLG, FLT2, KAL2, BFGFR, C-FGR, N-SAM | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| FGFR1 (W666R) | FGFR1 (W666R) | P11362 | FGFR-1, bFGF-R, FLT2, c-fgr | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR1(V561M) | FGFR1 (V561M) | P11362 | H2, H3, H4, H5, CEK, FLG, FLT2, KAL2, BFGFR, C-FGR, N-SAM | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR1OP- FGFR1 | CEP43-FGFR1 | O95684, P11362 | FOP, CEP43, FGFR1-FGFR1OP | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 | FGFR2 | P21802 | BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| FGFR2 (C491A) | FGFR2 (C491A) | P21802 | BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (C491F) | FGFR2 (C491F) | P21802 | BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (C491S) | FGFR2 (C491S) | P21802 | BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (C491S/V564L) | FGFR2 (C491S/V564L) | P21802 | Fibroblast growth factor receptor 2 [Precursor], Keratinocyte growth factor receptor 2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (E565G) | FGFR2 (E565G) | P21802 | BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (K526E) | FGFR2 (K526E) | P21802 | BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (K641R) | FGFR2 (K641R) | P21802 | BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (K659N) | FGFR2 (K659N) | P21802 | BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (N549H) | FGFR2 (N549H) | P21802 | BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (R612T) | FGFR2 (R612T) | P21802 | BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (V564F) | FGFR2 (V564F) | P21802 | BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, KGFR, KSAM, K-SAM, TK14, TK25 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (V564L) | FGFR2 (V564L) | P21802 | Fibroblast growth factor receptor 2 [Precursor], Keratinocyte growth factor receptor 2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR3 | FGFR3 | P22607 | ACH, CD333, CEK2, HSFGFR3EX, JTK4 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| FGFR3 (G697C) | FGFR3 (G697C) | P22607 | ACH, CD333, CEK2, HSFGFR3EX, JTK4 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR3 (K650E) | FGFR3 (K650E) | P22607 | ACH, CD333, CEK2, HSFGFR3EX, JTK4 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR3 (K650M) | FGFR3 (K650M) | P22607 | ACH, CD333, CEK2, HSFGFR3EX, JTK4 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR3 (K650Q) | FGFR3 (K650Q) | P22607 | ACH, CD333, CEK2, HSFGFR3EX, JTK4 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR3 (V555M) | FGFR3 (V555M) | P22607 | ACH, CD333, CEK2, HSFGFR3EX, JTK4 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR4 | FGFR4 | P22455 | TKF, JTK2, MGC20292 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| FGFR4 (N535K) | FGFR4 (N535K) | P22455 | TKF, JTK2, MGC20292 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR4 (V550E) | FGFR4 (V550E) | P22455 | TKF, JTK2, MGC20292 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR4 (V550L) | FGFR4 (V550L) | P22455 | TKF, JTK2, MGC20292 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR4 (V550M) | FGFR4 (V550M) | P22455 | TKF, JTK2, MGC20292 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGR | FGR | P09769 | SRC2, c-fgr, p55c-fgr | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| FLT1/VEGFR1 | FLT1 | P17948 | FLT, VEGFR1, FLT1, VEGF-R1 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| FLT3 | FLT3 | P36888 | FLK2, STK1, CD135 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| FLT3 (D835Y) | FLT3 (D835Y) | P36888 | FLK2, STK1, CD135 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FLT3 (F594_R595insR) | FLT3 (F594_R595insR) | P36888 | FLK2, STK1, CD135 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FLT3 (F594_R595insREY) | FLT3 (F594_R595insREY) | P36888 | FLK2, STK1, CD135 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FLT3 (ITD) | FLT3 (ITD) | P36888 | FLK2, STK1, CD135 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FLT3 (ITD)-NPOS | FLT3 (ITD)-NPOS | P36888 | FLK2, STK1, CD135 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FLT3 (ITD)-W51 | FLT3 (ITD)-W51 | P36888 | FLK2, STK1, CD135 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FLT3 (R595_E596insEY) | FLT3 (R595_E596insEY) | P36888 | FLK2, STK1, CD135 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FLT3 (Y591_V592insVDFREYEYD) | FLT3 (Y591_V592insVDFREYEYD) | P36888 | FLK2, STK1, CD135 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FLT4/VEGFR3 | FLT4 | P35916 | VEGFR3, PCL, VEGF-R3 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| FMS | CSF1R | P07333 | C-FMS, CD115, CSF-1-R, CSFR, FIM2, FMS, CSF1R | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| FRK/PTK5 | FRK | P42685 | PTK5, GTK, RAK | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| FYN | FYN | P06241 | SLK, SYN, p59-Fyn | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| FYN (Y531F) | FYN (Y531F) | P06241 | SLK, SYN, p59-Fyn | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| GCK/MAP4K2 | MAP4K2 | Q12851 | BL44, GCK, RAB8IP | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| GLK/MAP4K3 | MAP4K3 | Q8IVH8 | GLK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| GRK1 | GRK1 | Q15835 | RHOK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| GRK2 | GRK2 | P25098 | ADRBK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| GRK3 | GRK3 | P35626 | ADRBK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| GRK4 | GRK4 | P32298 | GPRK2L, GPRK4, GRK4a, IT11 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| GRK5 | GRK5 | P34947 | GPRK5 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| GRK6 | GRK6 | P43250 | GPRK6, FLJ32135 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| GRK7 | GRK7 | Q8WTQ7 | GPRK7 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| GSK3a | GSK3A | P49840 | GSK3alpha, GSK3a | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| GSK3b | GSK3B | P49841 | GSK3beta, GSK3b | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| Haspin | GSG2 | Q8TF76 | GSG2, Haspin | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| HCK | HCK | P08631 | JTK9 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| HGK/MAP4K4 | MAP4K4 | O95819 | HGK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| HIPK1 | HIPK1 | Q86Z02 | KIAA0630, MGC26642, MGC33446, Myak, Nbak2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| HIPK2 | HIPK2 | Q9H2X6 | PRO0593 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| HIPK3 | HIPK3 | Q9H422 | ANPK, DYRK6, FIST, FIST3, PKY, YAK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| HIPK4 | HIPK4 | Q8NE63 | FLJ32818 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| HPK1/MAP4K1 | MAP4K1 | Q92918 | HPK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| IGF1R | IGF1R | P08069 | JTK13, IGFR, CD221 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| IKKa/CHUK | CHUK | O15111 | IKBKA, IKK1, IKKA, NFKBIKA, TCF16, IKK-alpha, IKKalpha, IKKa | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| IKKb/IKBKB | IKBKB | O14920 | IKK2, IKKB, NFKBIKB, IKK-beta, IKKbeta | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| IKKe/IKBKE | IKBKE | Q14164 | IKKI, IKK-i, KIAA0151, IKK-epsilon, IKKepsilon | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| IR | INSR | P06213 | IR | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| IRAK1 | IRAK1 | P51617 | Pelle | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| IRAK2* | IRAK2 | O43187 | Interleukin-1 receptor-associated kinase-like 2 | HotSpot™ | Protein kinase | Not included in any panel | HotSpot |
| IRAK4 | IRAK4 | Q9NWZ3 | REN64 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| IRR/INSRR | INSRR | P14616 | IRR | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| ITK | ITK | Q08881 | EMT 2, LYK 2, PSCTK2 2 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| JAK1 | JAK1 (aa866-1154) | P23458 | JAK1A, JAK1B, JTK3 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| JAK2 | JAK2 | O60674 | JAK2 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| JAK2 (V617F) | JAK2 (V617F) | O60674 | JAK2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| JAK2 JH1&2* | JAK2 (JH1&2) | O60674 | JAK2 | HotSpot™ | Protein kinase | Not included in any panel | HotSpot |
| JAK3 | JAK3 | P52333 | JAKL, L-JAK, LJAK | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| JNK1 | MAPK8 | P45983-2 | PRKM8, SAPK1, JNK1-alpha1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| JNK2 | MAPK9 | P45984-1 | PRKM9, SAPK, p54a, JNK-alpha2, JNK2A, JNK2B | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| JNK3 | MAPK10 | P53779 | JNK3A, PRKM10, p493F12 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| KDR/VEGFR2 | KDR | P35968 | VEGFR2, FLK1, VEGF-R2 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| KHS/MAP4K5 | MAP4K5 | Q9Y4K4 | KHS1, GCKR, KHS, MAPKKKK5 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| KSR1 | KSR1 | Q8IVT5 | Kinase suppressor of Ras 1 | HotSpot™ | Protein kinase | Not included in any panel | HotSpotᵇ |
| KSR1 (A635F) | KSR1 (A635F) | Q8IVT5 | Kinase suppressor of Ras 1 | HotSpot™ | Protein kinase | Not included in any panel | HotSpotᵇ |
| KSR1 (L639F) | KSR1 (L639F) | Q8IVT5 | Kinase suppressor of Ras 1 | HotSpot™ | Protein kinase | Not included in any panel | HotSpotᵇ |
| KSR2 | KSR2 | Q6VAB6 | Kinase suppressor of Ras 2 | HotSpot™ | Protein kinase | Not included in any panel | HotSpotᵇ |
| KSR2 (R676S) | KSR2 (R676S) | Q6VAB6 | Kinase suppressor of Ras 2 | HotSpot™ | Protein kinase | Not included in any panel | HotSpotᵇ |
| LATS1 | LATS1 | O95835 | WARTS, wts | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| LATS2 | LATS2 | Q9NRM7 | FLJ13161, LATS | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| LCK | LCK | P06239 | LCK | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| LCK2/ICK | CILK1 | Q9UPZ9 | LCK2, ICK, MRK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| LIMK1 | LIMK1 | P53667 | LIMK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| LIMK2 | LIMK2 | P53671 | LIMK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| LKB1 | STK11 | Q15831 | LKB1, PJS | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| LOK/STK10 | STK10 | O94804 | LOK, PRO2729 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| LRRK2 | LRRK2 | Q5S007 | PARK8, ROCO2, FLJ45829, DKFZp434H2111 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| LRRK2 (G2019S) | LRRK2 (G2019S) | Q5S007 | PARK8, ROCO2, FLJ45829, DKFZp434H2111 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| LRRK2 (I2020T) | LRRK2 (I2020T) | Q5S007 | PARK8, ROCO2, FLJ45829, DKFZp434H2111 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| LRRK2 (R1441C) | LRRK2 (R1441C) | Q5S007 | PARK8, ROCO2, FLJ45829, DKFZp434H2111 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| LYN | LYN | P07948 | JTK8 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| LYNB | LYN (d23-43) | P07948-2 | JTK8 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| MAK | MAK | P20794 | MAK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MAPKAPK2 | MAPKAPK2 | P49137 | MAPKAPK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MAPKAPK3 | MAPKAPK3 | Q16644 | 3PK, MAPKAP, MAPKAP3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MAPKAPK5/PRAK | MAPKAPK5 | Q8IW41 | PRAK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MARK1 | MARK1 | Q9P0L2 | KIAA1477 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MARK2/PAR-1Ba | MARK2 | Q7KZI7-4 | EMK1, MGC99619, PAR-1Ba, ELKL | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| MARK3 | MARK3 | P27448 | CTAK1, KP78, PAR1A | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MARK4 | MARK4 | Q96L34 | KIAA1860, MARKL1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MAST3 | MAST3 | O60307 | Microtubule-associated serine/threonine-protein kinase 3, KIAA0561 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| MASTL | MASTL | Q96GX5 | GLW, GREATWALL, GWL, hGWL, THC2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MEK1 | MAP2K1 | Q02750 | MAPKK1, MKK1, PRKMK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| MEK1 (P124L) | MAP2K1 (P124L) | Q02750 | MAPKK1, MKK1, PRKMK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| MEK2 | MAP2K2 | P36507 | MAPKK2, MKK2, PRKMK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MEK3 | MAP2K3 | P46734 | MEK3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MEK5 | MAP2K5 | Q13163 | MAPKK5, MKK5, PRKMK5 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MEKK1 | MAP3K1 | Q13233 | MAPKKK1, MEKK, MEKK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| MEKK2 | MAP3K2 | Q9Y2U5 | MAPKKK2, MEKK2B | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MEKK3 | MAP3K3 | Q99759 | MAPKKK3, MEK kinase3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MEKK6 | MAP3K6 | O95382 | ASK2, MAPKKK6 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MELK | MELK | Q14680 | KIAA0175, PK38 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MELK (T460M) | MELK (T460M) | Q14680 | KIAA0175, PK38 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| MINK/MINK1 | MINK1 | Q8N4C8 | B55, YSK2, MAP4K6, ZC3, MINK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MKK4 | MAP2K4 | P45985 | JNKK, JNKK1, MAPKK4, MEK4, PRKMK4, SEK, SERK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MKK6 | MAP2K6 | P52564 | MAPKK6, MEK6, PRKMK6, SAPKK3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MKK7 | MAP2K7 | O14733 | MAPKK7, MEK7, PRKMK7 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MLCK/MYLK | MYLK | Q15746 | smMLCK, FLJ12216, KRP, MLCK, MLCK108, MLCK210 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MLCK2/MYLK2 | MYLK2 | Q9H1R3 | KMLC, skMLCK, MLCK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MLK1/MAP3K9 | MAP3K9 | P80192 | MLK1, PRKE1, MEKK9 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| MLK2/MAP3K10 | MAP3K10 | Q02779 | MLK2, MST, MEKK10 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MLK3/MAP3K11 | MAP3K11 | Q16584 | MGC17114, MLK-3, PTK1, SPRK, MLK3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MLK4 | MAP3K21 | Q5TCX8 | KIAA1804 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MNK1 | MKNK1 | Q9BUB5 | MNK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MNK2 | MKNK2 | Q9HBH9 | MNK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| MRCKa/CDC42BPA | CDC42BPA | Q5VT25 | MRCK-alpha, MRCKa | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MRCKb/CDC42BPB | CDC42BPB | Q9Y5S2 | MRCK-beta, MRCKb | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MSK1/RPS6KA5 | RPS6KA5 | O75582 | MSK1, RLPK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MSK2/RPS6KA4 | RPS6KA4 | O75676 | MSK2, RSK-B | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| MSSK1/STK23 | SRPK3 | Q9UPE1 | MSSK1, MGC102944, STK23 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MST1/STK4 | STK4 | Q13043 | MST1, KRS2, YSK3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| MST2/STK3 | STK3 | Q13188 | MST2, KRS1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MST3/STK24 | STK24 | Q9Y6E0 | MST3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MST4 | STK26 | Q9P289 | MASK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| mTOR/FRAP1 | MTOR | P42345 | FRAP1, FRAP, FRAP2, RAFT1, RAPT1 | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| MUSK | MUSK | O15146 | MUSK | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| MYLK3 | MYLK3 | Q32MK0 | caMLCK, MLCK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| MYLK4 | MYLK4 | Q86YV6 | Myosin light chain kinase family member 4 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MYO3A | MYO3A | Q8NEV4 | Myosin-IIIa | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| MYO3b | MYO3B | Q8WXR4 | MYO3b | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| NEK1 | NEK1 | Q96PY6 | KIAA1901, NY-REN-55, | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| NEK11 | NEK11 | Q8NG66 | FLJ23495 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| NEK2 | NEK2 | P51955 | NLK1, HsPK21, HsPK 21 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| NEK3 | NEK3 | Q8WUN5 | HSPK36, MGC29949 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| NEK4 | NEK4 | P51957 | NRK2, STK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| NEK5 | NEK5 | Q6P3R8 | MGC75495 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| NEK6 | NEK6 | Q9HC98 | SID6-1512 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| NEK7 | NEK7 | Q8TDX7 | NEK7 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| NEK8* | NEK8 | Q86SG6 | NEK8 | HotSpot™ | Protein kinase | Not included in any panel | HotSpot |
| NEK9 | NEK9 | Q8TD19 | DKFZp434D0935, MGC16714, NERCC, | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| NIK/MAP3K14* | MAP3K14 | Q99558 | NIK, FTDCR1B, HS, HSNIK | HotSpot™ | ADP-Glo | Protein kinase | Not included in any panel | HotSpotᵇ, ADP-Glo |
| NIM1 | NIM1K | Q8IY84 | NIM1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| NLK | NLK | Q9UBE8 | NLK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| OSR1/OXSR1 | OXSR1 | O95747 | OSR1, KIAA1101 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| p38a (T106M) | MAPK14 (T106M) | Q16539 | p38-alpha, CSBP, CSBP1, p38alpha, p38a | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| P38a/MAPK14 | MAPK14 | Q16539 | p38-alpha, CSBP, CSBP1, p38alpha, p38a | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| P38b/MAPK11 | MAPK11 | Q15759 | p38-beta, P38BETA2, PRKM11, SAPK2, p38beta, p38b | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| P38d/MAPK13 | MAPK13 | O15264 | p38-delta, PRKM13, SAPK4, p38delta, p38d | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| P38g/MAPK12 | MAPK12 | P53778 | p38-gamma, ERK3, ERK5, ERK6, p38gamma, p38g | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| P70S6K/RPS6KB1 | RPS6KB1 | P23443 | S6K, STK14A, P70S6K | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| P70S6Kb/RPS6KB2 | RPS6KB2 | Q9UBS0 | KLS, P70-beta-1, P70-beta-2, S6K-beta2, S6K2, SRK, p70S6Kb, S6K-beta, S6Kbeta | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| PAK1 | PAK1 | Q13153 | PAKalpha | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PAK2 | PAK2 | Q13177 | PAK65, PAKgamma | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PAK2 (Y443N) | PAK2 (Y443N) | Q13177 | PAK-2, PAK65, Gamma-PAK, S6/H4 kinase | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| PAK3 | PAK3 | O75914 | MRX30, OPHN3, PAK3beta, bPAK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PAK4 | PAK4 | O96013 | PAK4 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| PAK5 | PAK5 | Q9P286 | PAK7, PAK5, KIAA1264, MGC26232 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PAK6 | PAK6 | Q9NQU5 | PAK6, PAK5 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PASK | PASK | Q96RG2 | DKFZP434O051, DKFZp686P2031, KIAA0135, PASKIN, STK3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PBK/TOPK | PBK | Q96KB5 | TOPK, SPK, Nori-3, FLJ14385 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PDGFRa | PDGFRA | Q9DE49 | PDGFRalpha, PDGFR2, CD140a | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| PDGFRa(D842V) | PDGFRA (D842V) | Q9DE49 | PDGFRalpha, PDGFR2, CD140a | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| PDGFRa(G680R) | PDGFRA (G680R) | Q9DE49 | PDGFRalpha, PDGFR2, CD140a | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| PDGFRa(T674I) | PDGFRA (T674I) | Q9DE49 | PDGFRalpha, PDGFR2, CD140a | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| PDGFRa(V561D) | PDGFRA (V561D) | Q9DE49 | PDGFRalpha, PDGFR2, CD140a | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| PDGFRa-FIP1L1 | PDGFRA-FIP1L1 | Q6UN15, Q9DE49 | PDGFRalpha, PDGFR2, CD140a, FIP1L1-PDGFRA | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| PDGFRb | PDGFRB | P09619 | PDGFRbeta, JTK12, PDGFR, CD140B, PDGFR1 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| PDGFRb-TPM3 | PDGFRB-TPM3 | P06753, P09619 | PDGFRbeta, JTK12, PDGFR, CD140B, PDGFR1, TPM3-PDGFRB | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| PDK1/PDHK1 | PDK1 | Q15118 | PDHK1, Pyruvate dehydrogenase kinase | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| PDK1/PDPK1 | PDPK1 | O15530 | PDK1, PKB-like, 3-phosphoinositide-dependent protein kinase 1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PDK2/PDHK2 | PDK2 | Q15119 | PDHK2 | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| PDK3/PDHK3 | PDK3 | Q15120 | PDHK3 | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| PDK4/PDHK4 | PDK4 | Q16654 | PDHK4 | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| PEAK1 | PEAK1 | Q9H792 | PEAK1, KIAA2002 | HotSpot™ | Protein kinase | Not included in any panel | HotSpotᵇ |
| PHKg1 | PHKG1 | Q16816 | PHKg1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PHKg2 | PHKG2 | P15735 | PHKg2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PI3K (p110a(E542K)/p85a) | PIK3CA (E542K)-PIK3R1 | P42336, P27986 | MGC142161, MGC142163, p110-alpha, PI3K, PI3K-alpha | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PI3K (p110a(E545K)/p85a) | PIK3CA (E545K)-PIK3R1 | P42336, P27986 | MGC142161, MGC142163, p110-alpha, PI3K, PI3K-alpha | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PI3K (p110a(H1047R)/p85a) | PIK3CA (H1047R)-PIK3R1 | P42336, P27986 | MGC142161, MGC142163, p110-alpha, PI3K, PI3K-alpha | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PI3K (p110a/p65a) | PIK3CA-PIK3R1/p65a | P42336, P27986 | MGC142161, MGC142163, p110-alpha, PI3K, PI3K-alpha | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PI3Ka (p110a/p85a) | PIK3CA-PIK3R1 | P42336, P27986 | MGC142161, MGC142163, p110-alpha, PI3K, PI3K-alpha | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | Diversify Panel | ADP-Glo |
| PI3Kb (p110b/p85a) | PIK3CB-PIK3R1 | P42338, P27986 | PI3K, PI3KBETA, PIK3C1, p110-beta | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | Diversify Panel | ADP-Glo |
| PI3KC2a | PIK3C2A | O00443 | CPK, MGC142218, PI3-K-C2A | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PI3KC3 | PIK3C3 | Q8NEB9 | MGC61518, PI3-kinase type 3, PI3K type 3, Vps34 | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PI3Kd (p110d/p85a) | PIK3CD-PIK3R1 | O00329, P27986 | p110D, P110DELTA, PI3K, PI3K-delta, p110-delta | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | Diversify Panel | ADP-Glo |
| PI3Kg (p110g) | PIK3CG | P48736 | p120-PI3K, PI3CG, PI3K, PI3Kgamma, p110-gamma | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | Diversify Panel | ADP-Glo |
| PI4K2A | PI4K2A | Q9BTU6 | PI4KII, PIK42A, RP11-548K23.6 | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PI4Ka | PI4KA | P42356 | PIK4CA | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PI4Kb | PI4KB | Q9UBF8 | PIK4CB, NPIK | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PIM1 | PIM1 | P11309 | PIM | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PIM2 | PIM2 | Q9P1W9 | PIM2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PIM3 | PIM3 | Q86V86 | PIM3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| PIP5K1A | PIP5K1A | Q99755 | PIP5K1-alpha, PIP5KIalpha, PtdIns(4)P-5-kinase 1 alpha | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PIP5K1C | PIP5K1C | O60331 | PIP5K1-gamma, PIPKIg_v4 | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PKA | PRKACA | P17612 | PKACa | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| PKA (L206R) | PRKACA (L206R) | P17612 | PKACa | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| PKA-DNAJB1 | PRKACA-DNAJB1 | P25685, P17612 | PKACa, Hsp40, Sis1, RSPH16B | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| PKAcb | PRKACB | P22694 | PKAcb, MGC41879, MGC9320, PKA c-beta | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKAcg | PRKACG | P22612 | PKAcg | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKCa | PRKCA | P17252 | PRKACA, PKc-alpha, PKCa, PKCalpha | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| PKCb1 | PRKCB (1) | P05771 | PRKCB1, PKCB, PRKCB2, MGC41878, PKC-beta, PKC-beta1, PKCb1, PKCbeta1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKCb2 | PRKCB (2) | P05771-2 | PRKCB1, PKCB, PRKCB2, MGC41878, PKC-beta, PKC-beta2, PKCb2, PKCbeta2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKCd | PRKCD | Q05655 | MAY1, MGC49908, nPKC-delta, PKC-delta, PKCd, PKCdelta | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKCepsilon | PRKCE | Q02156 | PKCE, nPKC-epsilon, PKC-epsilon | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKCeta | PRKCH | P24723 | PKC-L, PKCL, PRKCL, nPKC-eta | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKCg | PRKCG | P05129 | PKCC, PKCG, SCA14, MGC57564, PKC-gamma, PKCgamma | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKCiota | PRKCI | P41743 | PKCI, DXS1179E, MGC26534, nPKC-iota | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKCmu/PRKD1 | PRKD1 | Q15139 | PKD1, PKD, PKCM, PKc-MU | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKCnu/PRKD3 | PRKD3 | O94806 | PKD3, EPK2, PKc-NU, PKD3, PRKCN | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKCtheta | PRKCQ | Q04759 | PRKCT, nPKC-theta | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| PKCzeta | PRKCZ | Q05513 | PKC2, PKCzeta | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKD2 (G870E) | PRKD2 (G870E) | Q9BZL6 | PKD2, HSPC187 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| PKD2/PRKD2 | PRKD2 | Q9BZL6 | PKD2, HSPC187 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKD2/PRKD2 (G848E) | PKD2/PRKD2 (G848E) | Q9BZL6 | nPKC-D2, KPCD2, PRKD2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| PKG1a | PRKG1 (a) | Q13976 | PKG1, PGK, PRKG1B, PRKGR1B | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKG1b | PRKG1 (b) | P14619 | PKG1, PGK, PRKG1B, PRKGR1B | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKG2/PRKG2 | PRKG2 | Q13237 | PKG2, cGKII, PRKGR2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKMYT1 | PKMYT1 | Q99640 | MYT1 | HotSpot™ | ADP-Glo | Probe-displacement | Protein kinase | Not included in any panel | HotSpotᵇ, ADP-Glo, Probe-displacement |
| PKMzeta | PRKCZ (aa184-592) | Q05513 | nPKC-zeta, PKC2, PKMzeta | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| PKN1-ANXA4 (Aex2Pex13) | PKN1-ANXA4 (Aex2Pex13) | Q16512, P09525 | PKN, PRK1, PRKCL1, Annexin A4 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| PKN1-TECR (Tex1Pex10) | PKN1-TECR | Q9NZ01, Q16512 | DBK, PKN, PAK1, PRK1, PRKCL1, MGC46204, TECR-PKN1, PKN1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| PKN1/PRK1 | PKN1 | Q16512 | DBK, PKN, PAK1, PRK1, PRKCL1, MGC46204, PKN1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKN2/PRK2 | PKN2 | Q16513 | PRK2, PRKCL2, PAK-2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PKN3/PRK3 | PKN3 | Q6P5Z2 | PRK3, PKNbeta, RP11-545E17.1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PLK1 | PLK1 | P53350 | STPK13 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| PLK2 | PLK2 | Q9NYY3 | SNK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PLK3 | PLK3 | Q9H4B4 | CNK, FNK, PRK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PLK4/SAK | PLK4 | O00444 | SAK, STK18 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PRKX | PRKX | P51817 | PKX1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| PYK2 | PTK2B | Q14289 | CADTK, CAKB, FADK2, FAK2, PKB, PTK, RAFTK, CAK beta | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| RAF1 | RAF1 (Y340D/Y341D) | P04049 | c-RAF | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| RAF1 (R391W) | RAF1 (R391W) | P04049 | c-RAF | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET | RET | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| RET (A883F) | RET (A883F) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (E732K) | RET (E732K) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (E762Q) | RET (E762Q) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (G691S) | RET (G691S) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (G810C) | RET (G810C) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (G810R) | RET (G810R) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (G810S) | RET (G810S) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (L730I) | RET (L730I) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (L730M) | RET (L730M) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (L790F) | RET (L790F) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (M918T) | RET (M918T) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (R749T) | RET (R749T) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (R813Q) | RET (R813Q) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (R912P) | RET (R912P) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (S891A) | RET (S891A) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (S904A) | RET (S904A) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (S904F) | RET (S904F) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (V738A) | RET (V738A) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (V778I) | RET (V778I) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (V804E) | RET (V804E) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (V804L) | RET (V804L) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (V804L)-KIF5B | RET (V804L)-KIF5B | P33176, P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, KIF5B-RET (V804L) | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (V804M) | RET (V804M) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (V804M)-KIF5B | RET (V804M)-KIF5B | P33176, P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, KIF5B-RET (V804M) | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (Y791F) | RET (Y791F) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (Y806C) | RET (Y806C) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (Y806H) | RET (Y806H) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (Y806N) | RET (Y806N) | P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET-BCR | RET-BCR | P11274, P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, BCR-RET | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET-CCDC6 (PTC1) | RET-CCDC6 | Q16204, P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, CCDC6-RET | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET-KIF5B (Kex15Rex14) | RET-KIF5B | P33176, P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, KIF5B-RET | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET-NCOA4 (PTC3) | RET-NCOA4 | Q13772, P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, NCOA4-RET | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET-PRKAR1A (PTC2) | RET-PRKARA1A | P10644, P07949 | CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, PRKARA1A-RET | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RIPK2 | RIPK2 | O43353 | CARD3, CARDIAK, CCK, GIG30, RICK, RIP-2, RIP2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| RIPK3* | RIPK3 | Q9Y572 | RIP3, receptor interacting protein 3 | HotSpot™ | Protein kinase | Not included in any panel | HotSpot |
| RIPK4 | RIPK4 | P57078 | Receptor interacting protein kinase 4, ANKK2, ANKRD3, DIK, MGC129992, MGC129993, PKK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| RIPK5 | DSTYK | Q6XUX3 | SgK496, SHIK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| ROCK1 | ROCK1 | Q13464 | P160ROCK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| ROCK2 | ROCK2 | O75116 | KIAA0619, ROC2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| RON/MST1R | MST1R | Q04912 | CD136, CDw136, PTK8, RON | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| ROS/ROS1 | ROS1 | P08922 | ROS, MCF3 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| ROS1 (G2032R) | ROS1 (G2032R) | P08922 | ROS, MCF3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ROS1 (G2101A) | ROS1 (G2101A) | P08922 | ROS, MCF3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ROS1 (G2101C) | ROS1 (G2101C) | P08922 | ROS, MCF3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ROS1-GOPC | ROS1-GOPC | Q9HD26, P08922 | ROS, MCF3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ROS1-TPM3 | ROS1-TPM3 | P06753, P08922 | ROS, MCF3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RSK1 | RPS6KA1 | Q15418 | RSK1, HU-1, MAPKAPK1, p90Rsk | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| RSK2 | RPS6KA3 | P51812 | RSK2, HU-3, MRX19, CLS | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| RSK2 (I416V) | RPS6KA3 (I416V) | P51812 | RSK2, HU-3, MRX19, CLS | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RSK2 (L608F) | RPS6KA3 (L608F) | P51812 | RSK2, HU-3, MRX19, CLS | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RSK3 | RPS6KA2 | Q15349 | RSK3, HU-2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| RSK4 | RPS6KA6 | Q9UK32 | RSK4 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| SBK1 | SBK1 | Q52WX2 | SH3-binding kinase 1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| SGK1 | SGK1 | O00141 | SGK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| SGK2 | SGK2 | Q9HBY8 | H-SGK2, dJ138B7.2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| SGK3/SGKL | SGK3 | Q96BR1 | CISK, SGK2, SGKL | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| SIK1 | SIK1 | P57059 | SIK, MSK, SNF1LK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| SIK2 | SIK2 | Q9H0K1 | QIK, SNF1LK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| SIK3 | SIK3 | Q9Y2K2 | L19, QSK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| SLK/STK2 | SLK | Q9H2G2 | KIAA0204, STK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| SNARK/NUAK2 | NUAK2 | Q9H093 | SNARK, DKFZp434J037 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| SNRK | SNRK | Q9NRH2 | SNF1-related kinase | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| SPHK1 | SPHK1 | Q9NYA1 | Sphingosine kinase 1 | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| SPHK2 | SPHK2 | Q9NRA0 | Sphingosine kinase 2 | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| SRMS | SRMS | Q9H3Y6 | C20orf148, SRM, dJ697K14.1 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| SRPK1 | SRPK1 | Q96SB4 | SFRSK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| SRPK2 | SRPK2 | P78362 | SFRSK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| SSTK/TSSK6 | TSSK6 | Q9BXA6 | FLJ24002, SSTK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| STK16 | STK16 | O75716 | TSF1, PKL12, MPSK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| STK21/CIT | CIT | O14578 | CRIK, STK21/CIT | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| STK22D/TSSK1 | TSSK1B | Q9BXA7 | TSSK1, FKSG81, SPOGA4, STK22D | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| STK25/YSK1 | STK25 | O00506 | YSK1, SOK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| STK32b/YANK2 | STK32B | Q9NY57 | YANK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| STK32c/YANK3 | STK32C | Q86UX6 | YANK3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| STK33 | STK33 | Q9BYT3 | STK33 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| STK38/NDR1 | STK38 | Q15208 | NDR1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| STK38L/NDR2 | STK38L | Q9Y2H1 | NDR2, KIAA0965 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| STK39/STLK3 | STK39 | Q9UEW8 | STLK3, DCHT, SPAK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| SYK | SYK | P43405 | SYK | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| TAK1 | MAP3K7 | O43318 | MAP3K7, TGF1a, MEKK7, TAK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| TAOK1 | TAOK1 | Q7L7X3 | TAO1, KIAA1361, MAP3K16, MARKK, | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| TAOK2/TAO1 | TAOK2 | Q9UL54 | KIAA0881, MAP3K17, PSK, PSK1, TAO1, TAO2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| TAOK3/JIK | TAOK3 | Q9H2K8 | DPK, JIK, MAP3K18, TAO kinase 3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| TBK1 | TBK1 | Q9UHD2 | CDC37, HSPCA, HSPCB, IKBKG, NAK, T2K, TANK, TRAF2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| TEC | TEC | P42680 | PSCTK4 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| TESK1 | TESK1 | Q15569 | TESK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| TESK2 | TESK2 | Q96S53 | TESK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| TGFBR2 | TGFBR2 | P37173 | HNPCC6, MFS2, RIIC, TGFbeta-RII, TBR-II, TRBII | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| TIE2 (A1124V) | TEK (A1124V) | Q02763 | VMCM, TIE-2, VMCM1, CD202B | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TIE2 (P883A) | TEK (P883A) | Q02763 | VMCM, TIE-2, VMCM1, CD202B | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TIE2 (R849W) | TEK (R849W) | Q02763 | VMCM, TIE-2, VMCM1, CD202B | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TIE2 (R915C) | TIE2 (R915C) | Q02763 | TIE-2, hTIE2, TEK, p140 TEK | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TIE2 (Y1108F) | TEK (Y1108F) | Q02763 | VMCM, TIE-2, VMCM1, CD202B | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TIE2 (Y897C) | TEK (Y897C) | Q02763 | VMCM, TIE-2, VMCM1, CD202B | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TIE2 (Y897H) | TIE2 (Y897H) | Q02763 | TIE-2, hTIE2, TEK, p140 TEK | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TIE2 (Y897H/R915C) | TIE2 (Y897H/R915C) | Q02763 | TIE-2, hTIE2, TEK, p140 TEK | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TIE2 (Y897S) | TEK (Y897S) | Q02763 | VMCM, TIE-2, VMCM1, CD202B | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TIE2/TEK | TEK | Q02763 | VMCM, TIE-2, VMCM1, CD202B | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| TLK1 | TLK1 | Q9UKI8 | PKU-beta, KIAA0137 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| TLK2 | TLK2 | Q86UE8 | MGC44450, PKU-ALPHA | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| TNIK | TNIK | Q9UKE5 | TRAF2 and NCK interacting kinase, KIAA0551, MAP4K7 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| TNK1 | TNK1 | Q13470 | TNK1 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| TRKA | NTRK1 | P04629 | MTC, TRK, TRK1 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| TRKA (A608D) | NTRK1 (A608D) | P04629 | MTC, TRK, TRK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKA (F589L) | NTRK1 (F589L) | P04629 | MTC, TRK, TRK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKA (G595R) | NTRK1 (G595R) | P04629 | MTC, TRK, TRK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKA (G595R/A608D) | NTRK1 (G595R/A608D) | P04629 | MTC, TRK, TRK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKA (G595R/G667A) | NTRK1 (G595R/G667A) | P04629 | MTC, TRK, TRK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKA (G595R/G667C) | NTRK1 (G595R/G667C) | P04629 | MTC, TRK, TRK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKA (G595R/G667S) | NTRK1 (G595R/G667S) | P04629 | MTC, TRK, TRK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKA (G595R/L657M) | NTRK1 (G595R/L657M) | P04629 | MTC, TRK, TRK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKA (G667C) | NTRK1 (G667C) | P04629 | MTC, TRK, TRK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKA (G667S) | NTRK1 (G667S) | P04629 | MTC, TRK, TRK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKA (L657M) | NTRK1 (L657M) | P04629 | MTC, TRK, TRK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKA-TFG | NTRK1-TFG | Q92734, P04629 | TRKA, TGF-NTRK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKA-TPM3 | NTRK1-TPM3 | P06753, P04629 | TRKA, TPM3-NTRK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKA-TPR | NTRK1-TPR | P12270, P04629 | TRKA, TPR-NTRK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKB | NTRK2 | Q16620 | GP145-TrkB | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| TRKC | NTRK3 | Q16288 | GP145-TrkC | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| TRKC (G623E) | NTRK3 (G623E) | Q16288 | GP145-TrkC | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKC (G623R) | NTRK3 (G623R) | Q16288 | GP145-TrkC | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKC (G623R/L686M) | NTRK3 (G623R/L686M) | Q16288 | GP145-TrkC | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKC (G696A) | NTRK3 (G696A) | Q16288 | GP145-TrkC | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKC (L686M) | NTRK3 (L686M) | Q16288 | GP145-TrkC | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRPM7/CHAK1 | TRPM7 | Q96QT4 | CHAK1 | HotSpot™ | Protein kinase | Bi-weekly Atypical Panel | HotSpot |
| TSSK2 | TSSK2 | Q96PF2 | DGS-G, SPOGA2, FLJ38613, TSK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| TSSK3/STK22C | TSSK3 | Q96PN8 | STK22C, STK22D, SPOGA3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| TTBK1 | TTBK1 | Q5TCY1 | KIAA1855, BDTK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| TTBK2 | TTBK2 | Q6IQ55 | KIAA0847 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| TTK* | TTK | P33981 | ESK, MPS1L1, MPS1, PYT | HotSpot™ | Protein kinase | Not included in any panel | HotSpot |
| TXK | TXK | P42681 | BTKL, PSCTK5, PTK4, RLK | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| TYK1/LTK | LTK | P29376 | TYK1 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| TYK2 | TYK2 | P29597 | JTK1 | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| TYRO3/SKY | TYRO3 | Q06418 | BYK, Brt, Dtk, Sky, Tif | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| ULK1 | ULK1 | O75385 | UNC51, Unc51.1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | Diversify Panel | HotSpot |
| ULK2 | ULK2 | Q8IYT8 | ATG1B, KIAA0623, Unc51.2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| ULK3 | ULK3 | Q6PHR2 | FLJ90566, DKFZP434C131 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| VRK1 | VRK1 | Q99986 | VRK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| VRK2 | VRK2 | Q86Y07 | VRK2 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| WEE1* | WEE1 | P30291 | WEE1hu | HotSpot™ | ADP-Glo | Probe-displacement | Protein kinase | Not included in any panel | HotSpot, ADP-Glo, Probe-displacement |
| WNK1 | WNK1 | Q9H4A3 | KDP, KIAA0344, PHA2C, PRKWNK1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| WNK2 | WNK2 | Q9Y3S1 | KIAA1760, NY-CO-43, P/OKcl.13, PRKWNK2, SDCCAG43 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| WNK3 | WNK3 | Q9BYP7 | KIAA1566, PRKWNK3 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| YES/YES1 | YES1 | P07947 | C-YES, HsT441, P61-YES, YES1, YES | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| YES1 (T348I) | YES1 (T348I) | P07947 | C-YES, HsT441, P61-YES, YES1, YES | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| YSK4/MAP3K19 | MAP3K19 | Q56UN5 | M3K19, RCK, YSK4 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| ZAK/MLTK | MAP3K20 | Q9NYL2 | MLTK, mlklak, ZAK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| ZAP70 | ZAP70 | P43403 | SRK, STD, TZK | HotSpot™ | Protein kinase | Tyrosine Kinase | Bi-weekly Wild Type Panel | HotSpot |
| ZAP70 (Y319F) | ZAP70 (Y319F) | P43403 | SRK, STD, TZK | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ZIPK/DAPK3 | DAPK3 | O43293 | ZIPK/DAPK3, ZIP, ZIPK | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| ROS1 (L2086F) | ROS1 (L2086F) | P08922 | ROS, MCF3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (N549K) | FGFR2 (N549K) | P21802 | Fibroblast growth factor receptor 2 [Precursor], Keratinocyte growth factor receptor 2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (V564I) | FGFR2 (V564I) | P21802 | Fibroblast growth factor receptor 2 [Precursor], Keratinocyte growth factor receptor 2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FLT3 (F691L/D835Y) | FLT3 (F691L/D835Y) | P36888 | FLK2, STK1, CD135 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FLT3 (Y591-V592insVDFREYEYD/D835Y) | FLT3 (Y591-V592insVDFREYEYD/D835Y) | P36888 | FLK2, STK1, CD135 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FLT3 (Y591-V592insVDFREYEYD/F691L) | FLT3 (Y591-V592insVDFREYEYD/F691L) | P36888 | FLK2, STK1, CD135 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (C491A/V564L) | FGFR2 (C491A/V564L) | P21802 | Fibroblast growth factor receptor 2 [Precursor], Keratinocyte growth factor receptor 2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (E565A) | FGFR2 (E565A) | P21802 | Fibroblast growth factor receptor 2 [Precursor], Keratinocyte growth factor receptor 2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (M420I) | FGFR2 (M420I) | P21802 | Fibroblast growth factor receptor 2 [Precursor], Keratinocyte growth factor receptor 2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ABL1 (Y245F) | ABL1 (Y245F) | P00519 | ABL, JTK7, p150, c-ABL, v-abl | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ABL1 (Y245F/Y412F) | ABL1 (Y245F/Y412F) | P00519 | ABL, JTK7, p150, c-ABL, v-abl | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-KIT (d557-558/Y823D) | KIT (d557-558/Y823D) | P10721 | C-Kit, PBT, CD117, SCFR | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (D770_N771insG) | EGFR (D770_N771insG) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (N771_P772insN) | EGFR (N771_P772insN) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (S768I) | EGFR (S768I) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| EGFR (V948R) | EGFR (V948R) | P00533 | EGF-R, ERBB, mENA, ERBB1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ERBB2 (V956R) | ERBB2 (V956R) | P04626 | NEU, NGL, HER2, TKR1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FGFR2 (C491A/V564I) | FGFR2 (C491A/V564I) | P21802 | Fibroblast growth factor receptor 2 [Precursor], Keratinocyte growth factor receptor 2 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| PIP4K2A | PIP4K2A | P48426 | PI42A, PI5P4KA, PIP5K2, PIP5K2A, PIP5KIII | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PIKFYVE | PIKFYVE | Q9Y2I7 | KIAA0981, PIP5K3 | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PIP4K2B | PIP4K2B | P78356 | PI42B, PIP5K2B | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PIP4K2C | PIP4K2C | Q8TBX8 | PI42C, PIP5K2C | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PI3KC2B | PI3KC2B | O00750 | P3C2B, PIK3C2B, C2-PI3K | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| c-KIT (N822K) | KIT (N822K) | P10721 | Mast/stem cell growth factor receptor, Proto-oncogene tyrosine-protein kinase c-kit | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| PIP5K1B | PIP5K1B | O14986 | STM7, PIP5K1-beta | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| DCAMKL3 | DCLK3 | Q9C098 | Serine/threonine-protein kinase DCLK3, Doublecortin domain-containing protein 3C, Doublecortin-like and CAM kinase-like 3, Doublecortin-like kinase 3, DCLK3, DCDC3C, KIAA1765 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| STK32A/YANK1 | STK32A | Q8WU08 | Serine/threonine-protein kinase 32A, Yet another novel kinase 1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| STK35/CLIK1 | STK35 | Q8TDR2 | Serine/threonine-protein kinase 35, CLP-36-interacting kinase 1, PDLIM1-interacting kinase 1, PDIK1, STK35L1 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| TSSK4 | TSSK4 | Q6SA08 | Testis-specific serine/threonine-protein kinase 4, Serine/threonine-protein kinase 22E, C14orf20, STK22E, TSSK5 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| ALK (I1171N/D1203N) | ALK (I1171N/D1203N) | Q9UM73 | ALK tyrosine kinase receptor, Anaplastic lymphoma kinase, CD246 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (D1213H) | MET (D1213H) | P08581 | c-Met, HGFR, MET | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| c-MET (R1227K) | MET (R1227K) | P08581 | c-Met, HGFR, MET | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| GAK | GAK | O14976 | Cyclin-G-associated kinase | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| GSK3b (C199A) | GSK3b (C199A) | P49841 | Glycogen synthase kinase-3 beta | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (V804M/G810S) | RET (V804M/G810S) | P07949 | Proto-oncogene tyrosine-protein kinase receptor ret, C-ret | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| RET (G810S/M918T) | RET (G810S/M918T) | P07949 | Proto-oncogene tyrosine-protein kinase receptor ret, C-ret | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TYK2 JH1 & JH2* | TYK2 (JH1&2) | P29597 | Non-receptor tyrosine-protein kinase TYK2 | HotSpot™ | Protein kinase | Not included in any panel | HotSpot |
| mDGKA* | DGKA Mouse | O88673 | DAG kinase alpha, 80 kDa diacylglycerol kinase, DAGK1 | ADP-Glo | Lipid kinase | Not included in any panel | ADP-Glo |
| rDGKA* | DGKA Rat | P51556 | DAG kinase alpha, 80 kDa diacylglycerol kinase, DAGK1 | ADP-Glo | Lipid kinase | Not included in any panel | ADP-Glo |
| mDGKZ* | DGKZ Mouse | Q80UP3 | Diacylglycerol kinase zeta, DAG kinase zeta, Dgkz | ADP-Glo | Lipid kinase | Not included in any panel | ADP-Glo |
| rDGKZ* | DGKZ Rat | O08560 | DAG kinase zeta, 104 kDa diacylglycerol kinase, DGK-IV, Dagk6 | ADP-Glo | Lipid kinase | Not included in any panel | ADP-Glo |
| CDK11B/Cyclin K* | CDK11B-CCNK | P21127, O75909 | Cyclin-dependent kinase 11B, CDC2L1, PITSLREA, PK58, CPR4, CCNK | HotSpot™ | Protein kinase | Not included in any panel | HotSpot |
| CLK4 (I363V) | CLK4 (I363V) | Q9HAZ1 | Dual specificity protein kinase CLK4, CDC-like kinase 4 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FLT3 (F691L) | FLT3 (F691L) | P36888 | FLK2, STK1, CD135 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ROS1 (F2004C) | ROS1 (F2004C) | P08922 | ROS, MCF3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| ROS1 (F2004I) | ROS1 (F2004I) | P08922 | ROS, MCF3 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| TRKA (G667A) | NTRK1 (G667A) | P04629 | MTC, TRK, TRK1 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| WEE2* | WEE2 | P0C1S8 | WEE1B | HotSpot™ | Protein kinase | Not included in any panel | HotSpot |
| ATR* | ATR | Q13535 | FRP1, Ataxia telangiectasia and Rad3-related protein, FRAP-related protein 1 | HTRF | Protein kinase | Not included in any panel | HTRF |
| RIPK1* | RIPK1 | Q13546 | RIP1, RIP | ADP-Glo | Protein kinase | Not included in any panel | ADP-Glo |
| AAK1* | AAK1 | Q2M2I8 | AP2-associated protein kinase 1, KIAA1048, Adaptor-associated kinase 1 | Probe-displacement | Protein kinase | Not included in any panel | Probe-displacement |
| CASK* | CASK | P07498 | CSN3, CSN10, CSNK, Kappa-casein | Probe-displacement | Protein kinase | Not included in any panel | Probe-displacement |
| IRAK3* | IRAK3 | Q9Y616 | IRAK-M | Probe-displacement | Protein kinase | Not included in any panel | Probe-displacement |
| PI3Kb (p110b/p85b) | PI3Kb (p110b/p85b) | P42338, O00459 | PIK3CB, PIK3C1 | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PI3KC2G/PIK3C2G | PI3KC2G/PIK3C2G | B7ZLY6 | PI3K-C2GAMMA, PI3K-C2-gamma | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| PI3K (p110a/p55g) | PI3K (p110a/p55g) | B7ZLY6, Q8N381 | PIK3CA, PIK3R3 | ADP-Glo | Lipid kinase | Bi-weekly Lipid Kinase Panel | ADP-Glo |
| JAK1 JH2* | JAK1 JH2 | P23458 | JAK1A, JAK1B, JTK3 | Probe-displacement | Protein kinase | Not included in any panel | Probe-displacement |
| JAK2 JH2* | JAK2 JH2 | O60674 | JAK2 | Probe-displacement | Protein kinase | Not included in any panel | Probe-displacement |
| TYK2 JH2* | TYK2 JH2 | P29597 | JTK1 | Probe-displacement | Protein kinase | Not included in any panel | Probe-displacement |
| c-SRC N1 | SRC | P12931 | ASV, SRC1, c-SRC, p60-Src | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| FLT3 (D835H) | FLT3 (D835H) | P36888 | FLK2, STK1, CD135 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FLT3 (D835V) | FLT3 (D835V) | P36888 | FLK2, STK1, CD135 | HotSpot™ | Protein kinase | Bi-weekly Mutant Panel | HotSpot |
| FYN-A | FYN | P06241 | SLK, SYN, p59-Fyn | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| HUNK | HUNK | P57058 | MAKV, B19 | HotSpot™ | Protein kinase | Bi-weekly Wild Type Panel | HotSpot |
| JAK3 JH1 & JH2* | JAK3 | P52333 | JAKL, L-JAK, LJAK | HotSpot™ | Protein kinase | Not included in any panel | HotSpot |
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* Kinase targets are not part of the bi-monthly screening panels
ᵇ Kinase targets are backordered, please inquire for more information
Legend of HGNC References
Fusion: ALK-TFG; fusion protein including TFG and ALK
Complex: CDK4-CCND1; a complex of CDK4 and Cyclin D1 via coexpression
Mutant or deletion: FGFR3 (G687C); FGFR3 point mutant substitution Glycin 687 to Cysteine
Fragment: FAK aa411-686; FAK comprising amino acids 411 to 686. Indicated only when two different constructs are available.
CD: catalytic domain fragment
FL: full length
Isoforms: PRKCB (2); PRKCB isoform 2